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These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
...
ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
A Clinical Guideline for the Diagnosis and Treatment of Drug-susceptible TB in Children and Adolescents
in South Africa. This new guidance is aligned with the updated WHO guidelines but has been adapted specifically for the South African context.
The intention of this publication is to provide g
...
uidance on the Diagnosis and treatment of TB in children and adolescents and they may be downloaded and distributed as required. Distribution for remuneration is not permitted. No changes to the content or format of this publication is permitted.
more
This document aims to provide Ministry of Health guidance on the implementation of PEP and PrEP to prevent HIV transmission and improve overall health outcomes. This comprehensive approach reflects
...
the commitment of all involved in combating HIV and enhancing public health.
more
The WHO publication “Surveillance, case investigation and contact tracing for mpox: interim guidance” provides updated global technical guidance on monitoring and responding to mpox (formerly known as monkeypox). It explains how countries should conduct surveillance to detect new outbreaks, car
...
ry out case investigation including clinical assessment and lab specimen collection, and perform contact tracing to monitor people exposed to confirmed or probable cases in order to stop transmission and protect at-risk groups. The guidance includes practical recommendations for how long contacts should be monitored (e.g., daily for 21 days without requiring quarantine if symptom-free) and advising good hygiene and reduced exposure risk during the monitoring period. This interim guidance is intended to support public health authorities worldwide in strengthening mpox outbreak detection, response, and reporting.
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The document Integrated Disease Surveillance and Response Technical Guidelines, Booklet Four: Sections 8 and 9 (Third Edition, 2019) provides guidance for strengthening public health surveillance and response systems in the WHO African Region. It fo
...
cuses on monitoring, supervision, evaluation, and feedback mechanisms to improve the performance and quality of Integrated Disease Surveillance and Response (IDSR) systems. The text outlines key surveillance core functions—such as case detection, reporting, data analysis, outbreak investigation, preparedness, response, and feedback—and introduces indicators to measure system effectiveness, including timeliness, completeness, and data quality. Additionally, it discusses the implementation of electronic IDSR (eIDSR) to enhance real-time reporting and outbreak management. Overall, the booklet aims to strengthen early detection, rapid response, and health security capacity across all levels of the health system.
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This guide defines public spaces for children as those that can be easily and freely accessed and enjoyed by all children, either alone or with friends or family, regardless of gender,
ethnicity, sexuality, nationality, social status or physical ability. Whatever their context, these places are saf
...
e from physical hazards (such as pollution, waste, traffic, falls or drowning risks); and social risks (such as crime, exclusion, or bullying). Whether they are streets, neighbourhoods, existing public open spaces, or the small, “liminal” spaces, such as stairwells or alleyways from which children carve out a place for themselves
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The Global hepatitis report 2026 provides the most comprehensive and up-to-date assessment of the global burden of hepatitis B (HBV) and hepatitis C (HCV), which together account for more than 95% of deaths related to viral hepatitis. Despite being preventable and treatable, viral hepatitis remains
...
one of the leading infectious disease killers worldwide.
The report also highlights the progress in response efforts at global, regional and country levels, in the context of global commitments, strategies and targets.
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Emergency Medical Teams 2030 strategy
recommended
The Emergency Medical Teams (EMT) initiative plays a vital role in building this stronger and
more resilient global health emergency architecture, both by driving its formation and by
contributing to a rapidly deployable global
...
health emergency corps. The Initiative and EMTs
bring something unique to health emergency preparedness and response – they bring
standards, professionalism, reliability, scalability, coordination, and the ability and willingness to
rapidly deploy wherever and whenever they are most needed. Most importantly, EMTs save lives.
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This new edition and fully updated publication replaces the 2012 UCG and is being circulated free of charge to all public and private sector prescribers, pharmacists, and regulatory authorities in the country