Africa Centers for Disease Control and Prevention (Africa CDC) is aware of the media releases of the preliminary results of a large randomized clinical trial conducted in the United Kingdom, which included dexamethasone, a corticosteroid, as one of the drugs used for the treatment of COVID-19 patien...ts. The investigators reported that administration of oral or injectable dexamethasone resulted in about one-third reduction in mortality among COVID-19 patientsi that required mechanical ventilation and about one-fifth for patients requiring oxygen.
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                                                                Guide d’urgence provisoire
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Int J Ment Health Syst. 2013 Jan 9;7(1):2. doi: 10.1186/1752-4458-7-2.
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                It is intended for use among clinicians taking care of moderate to severe COVID-19 cases.
The COVID-19 outbreak has brought with it the need for improved critical care for patients who develop severe disease. The majority of COVID-19 patients present with mild to moderate illness, 15% develop sever...e illness and about 5% develop critical conditions needing intensive care unit (ICU) care, requiring noninvasive or invasive ventilation
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                                                                Guideline
SAJHIVMED DECEMBER 2013, Vol. 14, No. 4
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Accessed January 22, 2019. 
This updated version include important research that has added to our knowledge about effective treatments for
child and adolescent depression. Its goal is to help parents and families make informed decisions about getting the best care for a child with depression. For ...easy use, it is presented in Frequently Asked Questions (FAQ) format.
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                                                                Le fonctionnement de la prise en charge des patients séropositifs au Bénin, le cas de l’Atacora
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                 This interim guidance to national health authorities and blood transfusion services outlines the steps required to collect convalescent whole blood (CWB) or plasma (CP) from Ebola virus disease (EVD) recovered patients for transfusion to patients with early EVD, as an empirical treatment modality.
...
Document contents:
    Guidance on donor selection, screening, donation and handling of blood and plasma units;
    guidance on transfusion of convalescent whole blood or plasma;
    other considerations.
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                                                                Deuxième d’une série consacrée à la prévention de la thrombose associée au cancer (Cancer-Associated Thrombosis, ou CAT en anglais), le présent article a pour but d’améliorer l’enseignement aux patients et leur état de santé. Le premier article, intitulé « Importance de la thromboe...mbolie veineuse liée au cancer », expliquait la pathologie ainsi que les lacunes cernées dans les connaissances des patients atteints de cancer (Sardo, Bayadinova, Jenkins et Penton, 2021). Il mettait en lumière le fait que ces patients reçoivent très peu d’information sur le risque de thromboembolie veineuse (TEV). Les stratégies proposées dans le présent article visent à sensibiliser les patients atteints de cancer à la TEV, à fournir des outils d’enseignement aux patients et, en fin de compte, à réduire le fardeau de la thrombose associée au cancer.
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                                                                Allergic rhinitis (AR) and asthma are inflammatory conditions of the airways that often occur concomitantly. This global survey was undertaken to understand patient perspectives regarding symptoms, treatments, and the impact on their well-being of comorbid AR and asthma.
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                n this study, low-dose azithromycin did not meet the prespecified non-inferiority margin compared with standard-dose azithromycin in achieving clinical and serological cure in PCR-confirmed active yaws. Only a single participant (with presumed latent yaws) had definitive serological failure. This wo...rk suggests that 20 mg/kg of azithromycin is probably effective against yaws, but further data are needed.
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                                                                Most of the global burden of sepsis occurs in low- and middle-income countries (LMICs), but the prevalence and etiology of sepsis in LMICs are not well understood. In particular, the lack of laboratory infrastructure in many LMICs has historically precluded an assessment of the pathogens leading to ...sepsis. A recent systematic review found that data describing antimicrobial resistance were absent for 43% of countries in Africa, and only two countries have national antimicrobial resistance plans. In addition, small studies have identified indiscriminate antibiotic use both in and out of hospital settings in sub-Saharan Africa. The absence of microbiological data and lack of antibiotic stewardship complicate sepsis management and almost certainly worsens outcomes, particularly in low-resource systems. The purpose of this study was to examine the prevalence, etiology, and outcomes of sepsis among a cohort of critically ill patients in a referral hospital of Malawi, with a focus on the prevalence of culture-confirmed bacteremia and urinary tract infections.
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                                                                DOI:https://doi.org/10.1016/S2213-2600(20)30316-7
The Lancet Respiratory Medicine
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                An evaluation of the prescribing patterns for under-five patients at a Tertiary Paediatric Hospital in Sierra Leone. J Basic Clin Pharma 2015;6:109-14.