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COVID-19: reminder of risk of serious side effects with chloroquine and hydroxychloroquine

European Medicine Agency (2020) CC

23 April 2020EMA/202483/2020 Rev Chloroquine and hydroxychloroquine are known to potentially cause heart rhythm problems, and these could be exacerbated if treatment is combined with other medicines, such as the antibiotic azithromycin, that have similar effects on the heart.

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COVID-19 Emergency Response: WASH and Infection Prevention and Control (IPC) in Health care facilities (HCF)

reliefweb (2020) C2

According to WHO, infection prevention and control (IPC) is a scientific approach and practical solution designed to prevent harm caused by infection to patients and health workers. It is grounded in infectious diseases, epidemiology, social science and health system strengthening. IPC occupies a un... more

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An agroecological Europe by 2050: What impact on land use, trade and global food security?

Schiavo M., Le Mouël C., Poux X., et. al. (2021) C2

This Study presents the key results of a research that analyses the implications of an ambitious agroecological transition across Europe, following the TYFA scenario. Published in 2018, what it proposes by 2050 is fully aligned with the objectives that the European Farm to Fork and Biodiversity stra... more

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Antimicrobial Resistance Background Document

National Department of Health South Africa (2019) C1

Antimicrobial resistance (AMR) is a multifaceted, international public health problem, which poses a direct threat to the safety of the population of South Africa. A national response is required to complement the development of a global plan, as articulated in the WHO’s draft resolution EB134/37 ... more

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Antimicrobial stewardship programmes in health-care facilities in low- and middle-income countries: a WHO practical toolkit. Online Course

Open WHO; World Health Organization WHO (2022) C_WHO

The toolkit provides guidance on where to get started, including the structures and resources that should be put in place at the national and health-care facility level, through a stepwise approach in low-resource settings. As the ultimate goal of an AMS programme is sustainable behaviour change in ... more

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Spatiotemporal distribution of antimicrobial resistant organisms in different water environments in urban and rural settings of Bangladesh

Asaduzzaman, M. et al. (2022) CC

The authors conduct an integrated survey of Antimicrobial Resistant Organisms (AMR) in drinking water, wastewater and surface water in three settings in Bangladesh: rural households, rural poultry farms, and urban food markets. Results show that untreated water discharged from rural households, poul... more

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Third progress analysis of implementation of antimicrobial resistance national action plans in the WHO South-East Asia Region

World Health Organization WHO (2022) C_WHO

Antimicrobial resistance (AMR) is described as a situation when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines, making infections harder or impossible to treat, and increasing the risk of disease spread, severe illness and death.1 AMR in recent years has... more

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Perfil de País Bolivia - Resistencia Antimicrobiana

SAIDI (South American Infections Diseases Initiative) (2009) C2

La publicación que aquí presentamos busca mostrar los resultados de la iniciativa SAIDI en los países intervenidos, para ello se entrega un perfil que muestra el panorama de la situación de la resistencia antimicrobiana, pre y post iniciativa, así como información clave de los actores que trab... more

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First meeting of the network on Buruli ulcer PCR laboratories in the WHO African Region Centre Pasteur du Cameroon, Yaoundé, 21–24 October 2019

World Health Organization WHO (2020) CC

Buruli ulcer is caused by infection with Mycobacterium ulcerans. The disease is reported in more than 33 countries worldwide, but only about half of these countries regularly report data to WHO; most cases are reported from subregions of West and Central Africa. The mode of transmission is not known... more

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Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer

Scherr, N.; R. Bieri, S.S. Thomas, et al. (2018) CC

Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... more

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Antimicrobial Resistance (AMR)

Deininger, K. The MEDBOX Team (2023) CC

Issue Brief 31: Antimicrobial resistance (AMR) can occur when viruses, bacteria, parasites and fungi change over time. There is no longer a response to medicines, and the infection treatment gets really difficult which increases the risk of a disesase spread, which can lead to severe health problems... more

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Design and validation of a trachomatous trichiasis-only survey: strategic and technical advisory group for neglected tropical diseases, working group on monitoring and evaluation

World Health Organization WHO (2017) CC

The Fifty-first World Health Assembly adopted resolution WHA51.11 in 1998, which targets the global elimination of trachoma as a public health problem by 2020 (1). The strategy recommended to achieve that goal is encapsulated by the acronym “SAFE”, which represents: Surgery for individuals wi... more

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Diseño y validación de una encuesta solo sobre triquiasis-tracomatosa: Grupo Consultivo estratégico y técnico para enfermedades tropicales desatendidas, Grupo de trabajo sobre Monitoreo y evaluación

World Health Organization WHO (2017) C_WHO

La quincuagésima primera Asamblea de la Salud Mundial aprobó la resolución WHA51.11 en 1998, que busca la eliminación mundial del tracoma como problema de salud pública para el 2020 (1). La estrategia recomendada para lograr ese objetivo está encapsulada por las siglas "SAFE", que represent... more

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Guidance on establishing national and local AMR surveillance systems in the Western Pacific Region

World Health Organization WHO (2024) C_WHO

Antimicrobial resistance (‎AMR)‎ is impacting our health, economies and development. Up to 5.2 million people may die because of resistant bacterial infections across the Western Pacific Region from 2020-2030. Childbirth, surgery, cancer treatment and other interventions will become impossibly d... more

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Clinical management of diphtheria: guideline

World Health Organization WHO (2024) C_WHO

WHO has published the first-ever guidance on the clinical management of diphtheria. The only previously available guidance was an operational protocol. The new guidance followed the rigorous process for developing guidance at WHO. It addresses the use of Diphtheria Antitoxin (DAT) in the treatmen... more

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Diphtheria - Vaccine-Preventable Diseases Surveillance Standards

World Health Organization WHO (2018) C_WHO

Diphtheria is caused by Corynebacterium species, mostly by toxin-producing Corynebacterium diphtheriae and rarely by toxin-producing strains of C. ulcerans and C. pseudotuberculosis. The most common type of diphtheria is classic respiratory diphtheria, whereby the exotoxin produced characteristicall... more

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Salud en las Américas. Mortalidad prematura potencialmente evitable

Pan American Health Organization (PAHO) (2024) C_WHO

En los últimos decenios, el estado general de salud de las personas ha mejorado considerablemente, lo que ha llevado a un aumento de la esperanza de vida al nacer en la mayor parte de los países de la Región de las Américas. Este progreso ha sido el resultado tanto de los avances en las tecnolog... more

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Status on national core elements for antimicrobial stewardship programmes in the WHO African Region

World Health Organisation (WHO) (2024) C_WHO

Antimicrobial resistance (AMR) is one of the world’s top 10 public health threats. The World Health Organization (WHO) in the African Region, using the Antimicrobial Stewardship assessment tool, has assessed Member States progress on strengthening national capacity need for effective implementatio... more

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COPD (acute exacerbation): antimicrobial prescribing

National Institute for Communicable Disease (NICE) National Institute for Communicable Disease (NICE) (2019) CC2

The NICE guideline NG114 provides recommendations on antimicrobial therapy for acute exacerbations of chronic obstructive pulmonary disease (COPD), aiming to optimize antibiotic use and minimize the development of antibiotic resistance.

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Prevalence, Etiology, and Outcome of Sepsis among Critically Ill Patients in Malawi

Prin, M.; Onofrey, L.; Purcell, L; et al. (2020) CC2

Most of the global burden of sepsis occurs in low- and middle-income countries (LMICs), but the prevalence and etiology of sepsis in LMICs are not well understood. In particular, the lack of laboratory infrastructure in many LMICs has historically precluded an assessment of the pathogens leading to ... more