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Guidelines for Management of ST-Elevated Myocardial Infarction
Directorate General of Health Services
Ministry of Health & Family Welfare Government of India
(2022)
CC
Myocardial infarctions are generally clinically classified into ST elevation MI (STEMI) and non-ST elevation MI (NSTEMI), based on changes in ECG. When blood flow to a part of the heart stops or the heart is injured and fails to receive enough oxygen required for its adequate functioning the conditi
...
on is termed as STEMI or the ‘heart-attack’ in laymen language. Patients with elevated cardiac troponin levels but negative CK-MB who were formerly diagnosed with unstable angina or minor myocardial injury are now reclassified as non-ST-segment elevation Myocardial Infarction (non-STEMI) even in the absence of diagnostic changes.
more
Asthma is the most common non-communicable disease in children and remains one of the most common throughout the life course. The great majority of the burden of this disease is seen in low-income and middle-income countries (LMICs), which have disproportionately high asthma-related mortality relati
...
ve to asthma prevalence. This is particularly true for many countries in sub-Saharan Africa. Although inhaled asthma treatments (particularly those containing inhaled corticosteroids) markedly reduce asthma morbidity and mortality, a substantial proportion of the children, adolescents, and adults with asthma in LMICs do not get to benefit from these, due to poor availability and affordability. In this review, we consider the reality faced by clinicians managing asthma in the primary and secondary care in sub-Saharan Africa and suggest how we might go about making diagnosis and treatment decisions in a range of resource-constrained scenarios. We also provide recommendations for research and policy, to help bridge the gap between current practice in sub-Saharan Africa and Global Initiative for Asthma (GINA) recommended diagnostic processes and treatment for children, adolescents, and adults with asthma.
more
April 2022 Volume 35 Issue 2 e00152-21
Population movements have turned Chagas disease (CD) into a global public health problem. Despite the successful implementation of subregional initiatives to control vectorial and transfusional Trypanosoma cruzi transmission in Latin American settings where t
...
he disease is endemic, congenital CD (cCD) remains a significant challenge. In countries where the disease is not endemic, vertical transmission plays a key role in CD expansion and is the main focus of its control. Although several health organizations provide general protocols for cCD control, its management in each geopolitical region depends on local authorities, which has resulted in a multitude of approaches. The aims of this review are to (i) describe the current global situation in CD management, with emphasis on congenital infection, and (ii) summarize the spectrum of available strategies, both official and unofficial, for cCD prevention and control in countries of endemicity and nonendemicity. From an economic point of view, the early detection and treatment of cCD are cost-effective. However, in countries where the disease is not endemic, national health policies for cCD control are nonexistent, and official regional protocols are scarce and restricted to Europe. Countries of endemicity have more protocols in place, but the implementation of diagnostic methods is hampered by economic constraints. Moreover, most protocols in both countries where the disease is endemic and those where it is not endemic have yet to incorporate recently developed technologies. The wide methodological diversity in cCD diagnostic algorithms reflects the lack of a consensus. This review may represent a first step toward the development of a common strategy, which will require the collaboration of health organizations, governments, and experts in the field.
more
Compendium of Animal Rabies Prevention and Control, 2016
Brown C.M., Slavinski S., Ettestad P. et al
National Association of State Public Health Veterinarians Compendium of Animal Rabies Prevention and Control Committee
(2016)
C2
Rabies is a fatal viral zoonosis and serious public health problem.1 All mammals are believed to be susceptible to the disease, and for the purposes of this document, use of the term animal refers to mammals. The disease is an acute, progressive encephalitis caused by viruses in the genus Lyssavirus
...
.
2 Rabies virus is the most important lyssavirus globally. In the
United States, multiple rabies virus variants are maintained in wild mammalian reservoir populations such as raccoons, skunks, foxes, and bats. Although the United States has been declared free from transmission of canine rabies virus variants, there is always a risk of reintroduction of these variants.The rabies virus is usually transmitted from animal to animal through bites. The incubation period is
highly variable. In domestic animals, it is generally 3 to 12 weeks, but can range from several days to months, exceeding 6 months.8 Rabies is communicable during the period of salivary shedding of rabies virus. Experimental and historic evidence documents that dogs, cats, and ferrets shed the virus for a few days prior to the onset of clinical signs and during illness. Clinical signs of rabies are variable and include inappetance, dysphagia, cranial nerve deficits, abnormal behavior, ataxia, paralysis, altered vocalization, and seizures. Progression to death is rapid. There are currently no known effective rabies antiviral drugs.
more
Plan Strategique National de Lutte contre le Paludisme 2020-2023 - République de Congo
Programme National de Lutte contre le Paludisme (PNLP)
Ministère de la Santé Publique, Hygiène et Prévention – République Démocratique du Congo
(2023)
C2
Le Plan Stratégique National de Lutte contre le Paludisme de la RDC vise à renforcer la communication pour le changement social et comportemental (CSC/CCC) dans la lutte contre le paludisme. Il a pour objectif d’améliorer les connaissances, attitudes et pratiques des populations pour encourager
...
l’adoption de comportements préventifs et curatifs.
Ce document propose une stratégie de communication structurée, basée sur une analyse contextuelle des comportements, croyances et obstacles sociaux. Il cible en priorité les femmes enceintes, les enfants de moins de cinq ans, les agents communautaires, les leaders religieux, les enseignants, et les médias. Les messages sont adaptés aux réalités locales et diffusés par des canaux variés : radios communautaires, théâtre, affiches, séances éducatives, et implication des leaders d'opinion.
Le plan insiste sur l’importance de la mobilisation sociale, de l’approche participative et du dialogue communautaire pour renforcer l’adhésion aux pratiques comme l’utilisation des moustiquaires imprégnées, le recours au test de diagnostic rapide, l’observance des traitements, et la fréquentation des centres de santé. Il prévoit aussi des mécanismes de suivi-évaluation et de renforcement des capacités des acteurs.
En résumé, ce document constitue un cadre opérationnel pour rendre la communication plus efficace, inclusive et durable dans la lutte contre le paludisme en RDC.
more
COVID-19 Diagnostics
recommended
ASLM strives to keep laboratory networks in Africa connected and informed of diagnostic tools, techniques, procedures and advancements related to COVID-19 testing with interactive training and information sessions using the Extended Community Health
...
Outcomes (ECHO) model and Massive Open Online Course (MOOC) platform from Future Learn.
more
Summary of current WHO recommendations and guidance on programmatic approaches
Глобальными приоритетами для лечения туберкулеза (ТБ) и борьбы с ним являются улучшенное и ранее выявление случаев туберкулеза, в том числе случаев заболевания с о
...
трицательным мазком мокроты, которые часто ассоциируются с вирусом иммунодефицита человека (ВИЧ) и ранним возрастом, а также расширенные возможности для диагностики туберкулеза с множественной лекарственной устойчивостью (МЛУ-ТБ)
more
3 March 2016
Guidance on pooled testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
recommended
The purpose of this document is to provide guidance on the use of pooled sample testing strategy in coronavirus disease (COVID-19)
testing laboratories of the African Union Member States for scaling up SARS-CoV-2 nucleic acid testing capacity with the available resources. The current document descr
...
ibes the effect of factors such as the prevalence of COVID-19 in the population to be tested, the homogeneity of pools, and the sensitivity of the molecular test in optimal pool size determination. It also highlights the importance of monitoring the prevalence of COVID-19 in a population to be tested and proper validation of the test, to limit the potential for false-negative results. Validation studies to determine the optimal pool size by testing laboratories are recommended as the optimum approach. A safe, simple ‘two-stage pooling’ option has been indicated in this guidance to be used by laboratories until such validation can be achieved.
more
Available in Arabic, Chinese, English, French, Portuguese, Russian and Spanish
https://apps.who.int/iris/handle/10665/334254
8 July 2020
