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Shorter treatment for children with minimal TB

SHINE Medical Research Council Clinical Trials Unit (MRC CTU) at UCL (2022) CC
The results of the SHINE trial have been published in the NEJM today. SHINE looked at whether treatment for children with minimal TB could be reduced from 6 months to 4 months. It found that the four month treatment was as good as the standard six months treatment for children with minimal TB
Wearing a face mask can help reduce the spread of COVID-19 in the community by reducing the release of respiratory droplets from asymptomatic / pre-symptomatic individuals or those with mild non-specific symptoms. The use of face masks for this purpose may be adopted to reduce the societal impact as ... more
Project Drawdown (2022) provides evidence of how climate solutions can also be win-win opportunities for meeting development and human well-being needs while boosting prosperity for rural communities in sub-Saharan Africa and South Asia. The report summarizes the co-benefits of five groups of a subs ... more
July 2021
The pharmaceutical sector of any nation is responsible for providing society with quality medicines and other pharmaceutical services. According to the World Health Organization (WHO), Pharmaceuticals may constitute as much as 40% of the national health budget in developing countries, yet portions o ... more
The Global Burden of Disease (GBD) 2010 Study has published disability-adjusted life year (DALY) data at both regional and country levels from 1990 to 2010. Concurrently, the Institute for Health Metrics and Evaluation (IHME) has published estimates of development assistance for health (DAH) at th ... more
Worldwide, there are about 17 million deaths due to cardiovascular disease (CVD) each year and at least two or three times as many non-fatal events. Raised cholesterol greatly increases the risks of stroke and heart disease, causing a large health burden across the world. The World Health Organizat ... more
Rivercess, Liberia, April 25, 2024 - Liberia marks a monumental milestone in its battle against malaria as it launches the highly anticipated RTS,S malaria vaccine today, coinciding with World Malaria Day, commemorated under the theme: Health Equity, Gender, and Human Rights: Accelerating the Figh ... more
Schweizerische Fachgesellschaft für Tropen‐ und Reisemedizin FMH
Digital health technology can make health systems more efficient and sustainable, facilitating the provision of high-quality care across a wide range of contexts and for diverse population health needs. The pace of innovation in digital health is rapid and constant, with new interventions bein ... more
Trop. Med. Infect. Dis. 2022, 7, 152. https://doi.org/10.3390/tropicalmed7080152
This document by Medicines for Malaria Venture (MMV) highlights the significant burden of malaria on children worldwide, emphasizing the need for effective prevention, diagnosis, and treatment strategies. It reviews current challenges and progress in combating pediatric malaria, advocating for conti ... more
Clinical Pharmacology: Advances and Applications, 2025:17 29–47
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex C
EDCTP Stakeholder meeting
Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
International Journal for Parasitology: Drugs and Drug Resistance Volume 28, August 2025, 100602 This review provides innovative insights to circumvent antimalarial drug resistance and diversify malaria therapeutics.
This issue brief aims to provide a comprehensive overview of key publications, guidelines, and practical materials on malaria prevention, diagnosis, and treatment. The selected documents reflect current evidence and field-based experiences, supporting healthcare professionals, researchers, and publ ... more
Lessons learned, ethical dilemmas, what failed, and what next? Presentation
In many countries neonatal tetanus is responsible for half of all neonatal deaths due to vaccine-preventable diseases and for almost 14% of al¡ infant deaths. It is estimated that in the 1970s more than 10,000 newborns died annually from neonatal tetanus in the Americas. Neonatal tetanus is prevent ... more