Journal of Infectious Diseases and Therapeutics, 2013, 1, 17-24
Article published in: Journal of Intensive Care (2015) 3:16
The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients wit...h DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.
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This publication is intended for professionals training or practicing in mental health and not for the general public. The opinions
expressed are those of the authors and do not necessarily represent the views of the Editor or IACAPAP. This publication seeks to
describe the best treatments and pra...ctices based on the scientific evidence available at the time of writing as evaluated by the authors and may change as a result of new research
Introduction - Chapter A.11
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This manual is to assist health care providers and laboratory scientists to diagnose mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the clinical presentation and its diagnosis. The methods described are tailored to various levels of care and avail...able resources to improve the diagnosis and surveillance of the disease.
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Interim rapid response guidance, 10 June 2022.
It includes considerations for certain populations such as patients with mild disease with considerations for community care, patients with moderate to severe disease, sexually active persons, pregnant or breastfeeding women, children and young persons.... The guidance also addresses considerations for clinical management such as the use of therapeutics, nutritional support, mental health services, and post-infection follow-up.
The document provides guidance for clinicians, health facility managers, health workers and infection prevention and control practitioners including but not limited to those working in primary care clinics, sexual health clinics, emergency departments, infectious diseases clinics, genitourinary clinics, dermatology clinics, maternity services, paediatrics, obstetrics and gynaecology and acute care facilities that provide care for patients with suspected or confirmed monkeypox
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August 2020.
Essential diagnostic products areconsidered an integral part of UHC, they are an indispensable element for delivery ofservices andare also a requirement for qualitycare. Despite this realization, a review of the UHC pilot in September 2019 es...tablished that whereas the Kenya Medical Supplies Authority (KEMSA) was able to fill up to 80% of pharmaceutical items, the order fill rate for diagnostic products was less than 50 percent for level 2 and 3 facilities and as low as 30 percent for level 4 and 5 facilities.
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SIGN 143. A national clinical guideline
Published May 2015, Revised 2018
La présente étude a permis, non seulement de mieux connaître les différents acteurs
de la ville de Cotonou sur la thématique du handicap, mais également de mettre en lumière
les actions qu’ils mènent. La problématique du handicap est mal connue dans la ville de
Cotonou : pas de statist...iques fiables (le dernier recensement national fait état de 2,55% de
personnes handicapées au sein la population nationale). Cependant, plus de 180
associations de personnes handicapées sont recensées sur le territoire national. Et bien que
le bénin soit signataire de nombreuses conventions et accords internationaux sur la
protection et la promotion des droits des personnes handicapées, il n’existe pas de
législation nationale spécifique, relative aux personnes handicapées. Il y a (trop !) peu de
campagnes officielles de sensibilisation sur les causes et la prévention du handicap, et les
commémorations conventionnelles passent souvent inaperçues. L’étude a permis de jeter
un regard sur les relations qu’ entretiennent les acteurs publics et associatifs entre eux.
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La présente étude a permis, non seulement de mieux connaître les différents acteurs
de la ville de Cotonou sur la thématique du handicap, mais également de mettre en lumière
les actions qu’ils mènent. La problématique du handicap est mal connue dans la ville de
Cotonou : pas de statist...iques fiables (le dernier recensement national fait état de 2,55% de
personnes handicapées au sein la population nationale). Cependant, plus de 180
associations de personnes handicapées sont recensées sur le territoire national. Et bien que
le bénin soit signataire de nombreuses conventions et accords internationaux sur la
protection et la promotion des droits des personnes handicapées, il n’existe pas de
législation nationale spécifique, relative aux personnes handicapées. Il y a (trop !) peu de
campagnes officielles de sensibilisation sur les causes et la prévention du handicap, et les
commémorations conventionnelles passent souvent inaperçues. L’étude a permis de jeter
un regard sur les relations qu’ entretiennent les acteurs publics et associatifs entre eux.
more
Seizures constitute the most common neurological problem in children and the majority of epilepsy has its onset in childhood. Appropriate diagnosis and management of childhood epilepsy is essential to improve quality of life in these children. Evidence-based clinical practice guidelines, modified to... the Indian setting by a panel of experts, are not available.
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