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Publication Years
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The pandemic has emphasized the high risk of avoidable harm to patients, health workers, and the general public, and has identified a range of safety gaps across all core components of health systems at all levels.
The rapid review ‘Implications of the
...
COVID-19 pandemic for patient safety’ explores impacts that the COVID-19 pandemic did have on patient safety in terms of risks and avoidable harm, specifically in terms of diagnostic, treatment and care management related issues as well as highlights the main patterns of these implications within the broader health system context.
more
This series of supportive tools are based on the WHO Therapeutics and COVID-19: living guideline. They are intended to provide supportive information for healthcare workers who are prescribing, admi
...
nistering and monitoring patients receiving nirmatrelvir-ritonavir for non-severe COVID-19.
more
Nirmatrelvir-ritonavir for COVID-19
recommended
This series of supportive tools are based on the WHO Therapeutics and COVID-19: living guideline. They are intended to provide supportive information for healthcare workers who are prescribing, admi
...
nistering and monitoring patients receiving nirmatrelvir-ritonavir for non-severe COVID-19.
more
Molnupiravir for COVID-19
recommended
This series of supportive tools are based on the WHO Therapeutics and COVID-19: living guideline. They are intended to provide supportive information for healthcare workers who are prescribing, admi
...
nistering and monitoring patients receiving nirmatrelvir-ritonavir for non-severe COVID-19.
more
Administration of Molnupiravir for COVID-19
recommended
This series of supportive tools are based on the WHO Therapeutics and COVID-19: living guideline. They are intended to provide supportive information for healthcare workers who are prescribing, admi
...
nistering and monitoring patients receiving nirmatrelvir-ritonavir for non-severe COVID-19.
more
Remdesivir for COVID-19
recommended
This series of supportive tools are based on the WHO Therapeutics and COVID-19: living guideline. They are intended to provide supportive information for healthcare workers who are prescribing, admi
...
nistering and monitoring patients receiving nirmatrelvir-ritonavir for non-severe COVID-19.
more
Administration of Remdesivir for COVID-19
recommended
This series of supportive tools are based on the WHO Therapeutics and COVID-19: living guideline. They are intended to provide supportive information for healthcare workers who are prescribing, admi
...
nistering and monitoring patients receiving nirmatrelvir-ritonavir for non-severe COVID-19.
more
For patients on HFNO with persistent hypoxaemia or respiratory distress:
• Check the equipment: inspect the exterior of the machine, the tubing (circuit), the prong for any sign of mechanical damage, confirm it fits and the filters are in place. Ensure the settings are appropriate and flow is max
...
imized.
• Check the oxygen source: there is sufficient oxygen available and flowing through the device. If FiO2 > 50% of oxygen is needed, the device must have a blender.
• Check there is no obstruction with secretions: patients with COVID-19 may have very thick secretions which may block small and large airways and cause sudden respiratory deterioration.
more
WHO recommends prompt recognition of progressive acute hypoxaemic respiratory failure when a patient with respiratory distress is failing to respond to standard oxygen therapy and adequate preparation to provide advanced oxygen/ventilatory support.
Hypoxaemic respiratory failure in ARDS commonly re
...
sults from intrapulmonary ventilation-perfusion mismatch or shunt and usually requires mechanical ventilation.
At any time, if there are urgent or emergent indications for intubation, do not delay.
WHO suggests that hospitalized patients with severe or critical COVID-19 with acute hypoxaemic respiratory failure that do not require emergent intubation be treated with HFNO, or CPAP or NIV (BiPAP) rather than standard oxygen therapy.
more
Management of critical COVID-19: Acute hypoxaemic respiratory failure and COVID-19: Recognize ARDS
recommended
WHO recommends prompt recognition of progressive acute hypoxaemic respiratory failure when a patient with respiratory distress is failing to respond to standard oxygen therapy and adequate preparation to provide advanced oxygen/ventilatory support.
Hypoxaemic respiratory failure in ARDS commonly
...
results from intrapulmonary ventilation-perfusion mismatch or shunt and usually requires mechanical ventilation.
At any time, if there are urgent or emergent indications for intubation, do not delay.
We recommend prompt recognition of progressive acute hypoxaemic respiratory failure when a patient with respiratory distress is failing to respond to standard oxygen therapy and adequate preparation to provide advanced oxygen/ventilatory support.
WHO suggests that patients with severe or critical COVID-19 with acute hypoxaemic respiratory failure that do not require emergent intubation be treated with HFNO, or CPAP or NIV (BiPAP) over standard oxygen therapy.
more
For patients on NIPPV or HFNO with persistent hypoxaemia or respiratory distress:
• Check the equipment: inspect the exterior of the machine, the tubing (circuit), the mask for any sign of mechanical damage, confirm it fits securely without leak (if CPAP/BiPAP) and the filters are in place. Ensur
...
e the settings are appropriate and flow is maximized.
• Check the oxygen source: there is sufficient oxygen available and flowing through the device. If FiO2 > 50% of oxygen is needed, the ventilator must have a blender.
• Check there is no obstruction with secretions: patients with COVID-19 may have very thick secretions which may block small and large airways and cause sudden respiratory deterioration.
more
This fact sheet highlights the relationship between alcohol consumption and COVID-19. Heavy episodic drinking is considered a health risk for COVID
...
-19, and alcohol is used by some to cope with difficult emotions that increased during the pandemic.
more
Esta ficha informativa destaca a relação entre o consumo de álcool e a COVID-19. O consumo episódico pesado é considerado um risco à saúde para a C
...
OVID-19, e o álcool é usado por alguns para lidar com as emoções difíceis que aumentaram durante a pandemia.
more
Esta hoja informativa destaca la relación entre el consumo de alcohol y la COVID-19. El alcohol se utiliza a menudo para la socialización y por algunas personas para hacer frente a las emociones d
...
ifíciles como la ansiedad, el miedo, la depresión, el aburrimiento y la incertidumbre, todo lo cual aumentó durante la pandemia de COVID-19, con el consiguiente incremento en el consumo de alcohol, especialmente en quienes ya bebían en exceso.
more
The World Health Organization (WHO) recognizes the challenges countries face for maintaining their COVID-19 response while addressing competing public health challenges, conflicts, climate change an
...
d economic crises.
It remains critical for national programmes to continue to offer testing for COVID-19 in line with three main objectives: reduce morbidity and mortality through linkage to prompt care and treatment, reduce onward transmission and track the evolution of the epidemic and the virus
itself.
more
Update, 23 de junio de 2022
Update, 23 de junio de 2022
Diferencias y similitudes del dengue y el COVID-19
During the COVID-19 pandemic, healthcare providers in areas where dengue is endemic or who are treating patients with recent travel history to these areas, need to consider dengue and
...
COVID-19 in the differential diagnosis of acute febrile illnesses.
more
As of 12 December 2022, over 645 million people worldwide have been diagnosed with COVID-19, with over 6.6 million deaths (4).
The Omicron variant, which emerged in late November 2021, and its subv
...
ariants, are now the dominant circulating viruses, contributing to the ongoing surge in several countries (4). Vaccination has substantially reduced case numbers and hospitalizations in many countries,but limitations in global access to vaccines mean that many populations, including those in low- and middle-income countries, remain vulnerable. Even in vaccinated individuals, uncertainties remain about duration of protection and efficacy, and the degree of crossprotection with new variants.
There remains a need for more effective treatment and management for those affected by COVID-19. The pandemic – and the
explosion of both research and misinformation – has highlighted the need for trustworthy, accessible and regularly updated living
guidelines to place emerging findings into context and provide clear recommendations for clinical practice
more
