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The technical note from the Global Task Force on Cholera Control (GTFCC) examines the risks and benefits of vaccinating pregnant women with WHO-prequalified oral cholera vaccines (OCVs) during mass vaccination campaigns. It highlights that three WHO-approved vaccines (Dukoral®, Shanchol™, and Euv
...
ichol®) offer sustained protection and a strong safety profile.
While these vaccines are not explicitly contraindicated for pregnant women, there is limited clinical data on their use during pregnancy. However, studies indicate that pregnant women with cholera face higher risks of fetal loss, stillbirth, and complications, especially if they experience severe dehydration. Some evidence suggests that vaccination can reduce cholera incidence in pregnant women and indirectly protect infants.
Although no controlled trials have focused on pregnant women, retrospective studies in Guinea and Zanzibar showed no significant increase in adverse pregnancy outcomes after OCV administration. The GTFCC concludes that the benefits of vaccination outweigh the risks, particularly in high-risk areas, and recommends including pregnant women in cholera vaccination campaigns while continuing to monitor safety data.
more
Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 23, No. 11, November 2017
NEMLIST | Sixth Edition | February 2016
Capability and Performance
Accessed November, 2017
CORE Group has developed a module on cholera to address gaps in preparedness and response in at-risk countries and communities. The guide contains four different lesson plans and is complemented by flipcharts designed for use by community health workers. The lessons are aimed at mothers and carers o
...
f children under the age of five, as this age group is at increased risk of dying from cholera. The modules include measures that can be taken before, during and after a cholera outbreak
more
Key Populations Brief
Accessed November 2017
Background paper 8
The Independent Panel for Pandemic Preparedness and Response
May 2021