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Direct acting antivirals (DAAs) have revolutionized treatment for hepatitis C. Combi-
nations of DAAs can cure infection with HCV in 12 weeks, are highly effective and
have limited side-effects. Affordability of DAAs has improved significantly, but access remains lim-
i
...
ted. Initially, due to their high prices, affordability of DAAs was limited in high-, middle- and low-
income countries alike. Now there is a divide between those countries where, because of intellectual
property barriers, prices have remained (very) high and other countries where generics are, or can be,
available at much lower prices. The result is a dual market
more
РУКОВОДСТВО ДЛЯ АКТИВИСТОВ ПО ИНСТРУМЕНТАМ ДЛЯ ДИАГНОСТИКИ ТУБЕРКУЛЕЗА ЯНВАРЬ.
Leptospirosis is a zoonotic disease with epidemic potential, especially after a heavy rainfall,
caused by a bacterium called Leptospira. Leptospira interrogans is pathogenic to humans and
animals, with more than 200 serologic variants or serovars. Humans usually acquire
leptospirosis through dire
...
ct contact with the urine of infected animals or a urine-contaminated
environment. Human-to-human transmission occurs only very rarely. Leptospirosis may present
with a wide variety of clinical manifestations, from a mild illness that may progress to a serious
and sometimes fatal disease. Its symptoms may mimic many diseases, such as influenza,
dengue and other viral haemorrhagic diseases; making the correct diagnosis (clinical and
laboratory) at the onset of symptoms is important to prevent severe cases and save lives,
primarily in outbreak situations.
more
Guidelines for the management of asthma in adults and adolescents: Position statement of the South African Thoracic Society – 2021 update
Lalloo, U.G.; Kalla, I.S.; Abdool-Gaffar, S. et al.
African Journal of Thoracic and Critical Care Medicine
(2021)
CC
sthma prevalence is increasing worldwide, and surveys indicate that most patients in developed and developing countries, including South Africa, do not receive optimal care and are therefore not well controlled. Standard management guidelines adapted to in-country realities are important to support
...
optimal care. The South African Thoracic Society (SATS) first published a guideline for the management of chronic persistent asthma in 1992, which has subsequently been revised several times.
The main aim of the present document was to revise and update SATS’ statement on the suggested management of chronic asthma, based on the need to promote optimal care and control of asthma, together with the incorporation of new concepts and drug developments. This revised document reinforces optimal care and incorporates the following primary objectives to achieve the recent advances in asthma care:
• continued emphasis on the use of inhaled corticosteroids (ICS) as the foundation of asthma treatment
• to reduce the reliance on short-acting beta-2 agonist (SABA) monotherapy for asthma symptoms
• to incorporate the evidence and strategy for the use of the combination of an ICS and formoterol for acute symptom relief (instead of a SABA)
• to incorporate the evidence and strategy for the use of as-needed ICS-long-acting beta agonists (LABA) for patients with infrequent symptoms or ‘mild’ asthma
• to incorporate the evidence and strategy for the use of a long-acting muscarinic antagonist (LAMA) in combination with ICS-LABA; and
• to incorporate the evidence and strategy for the use of and management with a biologic therapy in severe asthma.
more
End TB.
Accessed in November 2017.
Framework for implementation.
The END TB Strategy.
Prevalence of drug-resistant tuberculosis in Nigeria: A systematic review and metaanalysis
C. C. Onyedum, I. Alobu, K. N. Ukwaja
PLOS One; O. Neyrolles (Institut de Pharmacologie et de Biologoie Structurale)
(2017)
CC
PLoS ONE 12(7): e0180996. https://doi.org/10.1371/journal.pone.0180996
Advocacy report March 2011
303100 03/2011 E 1,000
Accessed November 2017
Regulation of the Minister of Health of the Republic of Indonesia concerning guidelines for implementation of opioid replacement therapy program
Accessed November 2017
Scientific advice
Prevention and control of communicable diseases in prison settings.
Management, control and prevention of tuberculosis - Guidelines for health care providers
Prof. C. Abobltins, L. Brown, Prof N. Curtis, et al.
Department of Health & Human Services; State Goverment Victoria
(2015)
C2
On the road to ending TB
Highlights from the 30 highest TB burden countries
The END TB Strategy
Towards a world free of tuberculosis
