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Africa CDC Dashboard COVID-19
recommended

Africa Centres for Disease Control and Prevention (Africa CDC) (2022) CC
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COVID-19 - PAHO/WHO Response Situation Updates
recommended

Pan American Health Organisation PAHO (2022) C_WHO
Please download the latest report directly from here: https://www.paho.org/en/tag/covid-19-situation-reports
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COVID-19 Observatory in Latin America and the Caribbean. Economic and social impact

ECLAC (2022) CC
The new global scenario in times of COVID-19 makes it necessary to take urgent measures and assess the impacts they will have. ECLAC has built this Observatory to support review and follow-up over the medium and long terms and at the request of CELAC. The Observatory tracks the public policies that ... more
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Core Indicators Americas

Pan American Health Organisation PAHO (2022) C_WHO
PAHO Core Indicators provide the latest data on health indicators for the Region of the Americas, a few of which may be explored in the visualization below. This dataset is composed of about 200 health and health related indicators from 1995 to 2021 for 49 countries and territories in the Region of ... more
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Portal de indicatores básicos Américas

Pan American Health Organisation PAHO (2022) CC
Los indicadores básicos de la OPS proporcionan los datos más recientes sobre indicadores de salud para la Región de las Américas, tales como los ejemplos que se muestran abajo. Este conjunto de datos se compone de cerca de 200 indicadores de salud y relacionados con la salud de 1995 a 2021 para ... more
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Progress towards elimination of lymphatic filariasis in the Americas region

G. Fontes, da Rocha, E. M. M.; Carvalho Scholte, R. G.; et al. International Health (2020) C1
In South and Central America, lymphatic filariasis (LF) is caused by Wuchereria bancrofti, which is transmitted by Culex quinquefasciatus, the only vector species in this region. Of the seven countries considered endemic for LF in the Americas in the last decade, Costa Rica, Suriname and Trinidad a... more
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Providing information, education and communication for key people involved in Chagas disease control

World Health Organization WHO (2022) CC
The Information, education and communication (IEC) activities, with the development of contextualized activities for various actors and scenarios about preventative measures and surveillance tools, are essential to increase awareness, reduce biomedical and psychosocial barriers to accessing diagnosi... more
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Chagas Disease: From Discovery to a Worldwide Health Problem Infectious Diseases

Freitas Lidani, K.; Antunes Andrade, F.; Bavia, L.; et. al. Frontiers Public Health (2019) CC
Front. Public Health, 02 July 2019 Sec. Infectious Diseases: Epidemiology and Prevention Volume 7 - 2019 | https://doi.org/10.3389/fpubh.2019.00166 Chagas disease (CD) is an anthropozoonosis caused by the protozoan parasite Trypanosoma cruzi, that affects about 6–8 million people worldwide (1) a... more
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What is Chagas disease?

Medical News Today (2020) C1
Chagas disease, or American trypanosomiasis, is a condition that causes gradual organ damage. Without treatment, it can be fatal. This article explains where the T. cruzi parasite is most common and how it can spread. It also outlines the symptoms of Chagas disease and the treatment options avail... more
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Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership.

Bernhard, S.; Kaiser, M.; Burri, C.; Mäser, P. Diseases (2022) CC
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery for HAT with special emphasis on the discovery, pre-clinical development, and operational challenge... more
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Treatment options for second-stage gambiense human African trypanosomiasis

Eperon, G.; Balasegaram, M.; Potet, J.; Mowbray, C.; Valverde, O.; ois Chappui, F. Informa Healthcare (2014) CC
Treatment of second-stage gambiense human African trypanosomiasis relied on toxicarsenic-based derivatives for over 50 years. The availability and subsequent use of eflornithine,initially in monotherapy and more recently in combination with nifurtimox (NECT), has drasticallyimproved the pro... more
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New Therapeutics for Chagas Disease: Charting a Course to Drug Approval

Man, A. & Segal, F. IntechOpen (2022) CC
Little progress has been made since the 1960s and 1970s to widen the therapeutic arsenal against Trypanosoma cruzi, the causative pathogen of Chagas disease, which remains a frustrating and perplexing infectious disease. This chapter focuses on the strategic and operational challenges in the clinica... more
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Epidemiology of Chagas disease in pregnant women and congenital transmission of Trypanosoma cruzi in the Americas: systematic review and meta-analysis

Santana, K.; Oliveira, L.; Barros de Castro, D. et al. Tropical medicine & international health (2020) CC
Objective To estimate the prevalence of Chagas disease in pregnant women and the vertical transmission of the disease. Methods Observational studies were identified from eight electronic databases, and details on study design, population and prevalence of Chagas disease were extracted. The data... more
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An Update on the Knowledge of Parasite–Vector Interactions of Chagas Disease

Schaub, G. Research and Reports in Tropical Medicine (2022) CC
This review focusses on the interactions between the etiologic agent of Chagas disease, Trypanosoma cruzi, and its triatomine vector. The flagellate mainly colonizes the intestinal tract of the insect. The effect of triatomines on trypanosomes is indicated by susceptibility and refractoriness phenom... more
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Reimagining the fight against Chagas disease

Novartis (2020) C1
Chagas disease affects approximately 6 million people, mainly in Latin America. Less than 1% of affected individuals receive proper antiparasitic treatment, and current drugs are inadequate to fight the entire spectrum of the disease. Against this background, Novartis is pursuing an end-to-end appro... more
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Chagas Disease Treatment Market Huge Growth in Future Scope 2023-2030

Coherent Market Insights Digital Journal (2023) C1
Coherent Market Insights has announced the addition of Chagas Disease Treatment Market 2023 Forecast Analysis by Types, Applications, Size, Share, Key Players, and Regions. a new research report to its market research archive. The Chagas Disease Treatment Market has been thoroughly researched and an... more
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Leishmaniasis Key Facts

Pan American Health Organization (PAHO) World Health Organization (WHO) (2022) C_WHO
Leishmaniasis is a vector-borne disease with a wide variety of parasite species, reservoirs, and vectors involved in transmission. It is caused by different species of the protozoa Leishmania and is transmitted to animals and humans through a bite of insects in the Psychodidae family. Its presence i... more
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Cutaneous Leishmaniasis: Urgent need to develop more effective and user-friendly point-of-care diagnostic tools

DNDi redeLEISH (2022) CC
Leishmaniasis is a complex vector-borne disease involving in its transmission several species of protozoan parasites called Leishmania, a wide variety of animal reservoirs and phlebotomine sandflies vectors. Cutaneous Leishmaniasis (CL) is the most common form of the disease, and its clinical manife... more
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The elimination of human African trypanosomiasis: Achievements in relation to WHO road map targets for 2020

Franco JR, Cecchi G, Paone M, Diarra A, Grout L, et al. (2022) CC
Human African trypanosomiasis (HAT) is a lethal neglected tropical disease (NTD) transmitted by the bite of infected tsetse flies. The disease is also known as “sleeping sickness”. During the 20th century it caused enormous suffering in the endemic areas in sub-Saharan Africa. HAT transmission l... more
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Rethinking the Top-Down Approach to Schistosomiasis Control and Elimination in Sub-Saharan Africa

Onasanya A. et al. (2021) CC
The control and elimination of schistosomiasis have over the last two decades involved several strategies, with the current strategy by the World Health Organization (WHO) focusing mainly on treatment with praziquantel during mass drug administration (MDA). However, the disease context is complex wi... more