Silicosis is not a new disease; the impact of silica dust on respiratory function was observed by Hippocrates in 430 B.C. and in the 16th century by Agricol. In 1713, Rammazini described silicotic nodules in post-mortems of stone cutters presenting with respiratory symptoms. In the mid-late 1800s,... the introduction of mechanized tools in the mining sector rapidly increased levels of silica exposure, resulting in an increase in cases and our understanding of silicosis.
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Secondhand smoke and the harmful chemicals in it are known causes of Sudden Infant Death Syndrome RESPIRATORY INFECTIONS, ear infections.and asthma attacks in infants and children. They are also known causes of HEART DISEASE,stroke, and lung cancer in adult nonsmokers.
Severe and difficult asthma in a low- and middle-income country (LMIC) can relate to lack of availability of basic medications; potentially reversible factors such as poor adherence or comorbidities such as obesity inhibiting a good response to treatment; and (rarely) true severe, therapy-resistant ...asthma. However, definitions of severity should encompass not merely doses of prescribed medication, but also underlying risk. The nature of asthmatic airway disease shows geographical variation, and LMIC asthma should not be assumed to be phenotypically the same as that in high-income countries (HICs). The first assessment step is to ensure another diagnosis is not being missed. Largely, political action is needed if children with asthma are to get access to basic medications. If a child is apparently not responding to low dose, simple medications, the next step is not to increase the dose but perform a detailed assessment of what factors (for example co-morbidities such as obesity, or social factors like poor adherence) are inhibiting a treatment response; in most cases, an underlying reason can be found. An assessment of risk of future severe asthma attacks, side-effects of medication and impaired lung development is also important. True severe, therapy-resistant asthma is rare and there are multiple underlying molecular pathologies. In HICs, steroid-resistant eosinophilia would be treated with omalizumab or mepolizumab, but the cost of these is prohibitive in LMICs, the biomarkers of successful therapy are likely only relevant to HICs. In LMICs, a raised blood eosinophil count may be due to parasites, so treating asthma based on the blood eosinophil count may not be appropriate in these settings.
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Secondhand smoke can infiltrate into other units through hallways and stairwells. Don’t be shy when it comes to your health. Talk to your building manager about making your apartment smokefree.
There is no safe level of secondhand smoke exposure
Secondhand smoke can travel within multiunit housing and common areas through doorways, cracks in walls, electrical lines, ventilation systems and plumbing.
Opening windows and using fans does not completely remove secondhand smoke.
Heating, air... conditioning and ventilation systems cannot eliminate exposure to secondhand smoke.
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a "risk factor" is something that increases your chances of getting a disease or condition. In the case of asthma there are two diffrent type of risk factors. There are risk factors for developing asthma , and there are separate risk factors for those who already have asthma getting a severe asthma ...attack. We like to refer to the second as "triggers for asthma attacks" instead of "risk factors" to avoid confusion.
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