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First published in 2020, this toolkit is intended for clinicians working in acute care, managing adult and paediatric patients with acute respiratory infection, including severe pneumonia, acute respiratory distress syndrome, sepsis and septic shock. The main objective is to provide key tools for us ... more
Toolkit HIV Treatment and Care
The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping laboratory services producing comparable and reliable ... more
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches. HIV drug resistance has been rarely reported among PrEP users who tested HIV positive i ... more
Accessed Febr. 6, 2020
30 April 2020 | COVID-19: Essential health services
The following protocol has been designed to investigate the First Few X cases (FFX) and their close contacts. It is envisioned that the FFX 2019-nCoV investigation will be conducted across several countries or sites with geographical and demographical diversity. Using a standardized protocol such a ... more
This document is intended for use by state and local health departments and healthcare facilities and serves as general guidance for the initial response for the containment of novel or targeted multidrug-resistant organisms (MDROs) or resistance mechanisms. It is not intended to describe all the ac ... more
Quality clinical care is at the heart of a robust, effective response to outbreaks. Frontline health workers need evidence-based tools and training to provide safe, effective and quality clinical care. The Clinical Management channel includes videos on a range of diseases, such as Ebola, diphther ... more
Molecular methods for antimicrobial resistance (AMR)diagnostics to enhance the Global Antimicrobial Resistance Surveillance System
On the 31st December 2019, the World Health Organization (WHO) China country office reported a cluster of pneumonia cases in Wuhan City, Hubei Province of China now known to be caused by a novel virus. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been confirmed as the causative v ... more
1. What is COVID-19? 2. Who is at most risk for COVID-19? 3. What is the risk of COVID-19 infection in humans in South Africa? 4. How is COVID-19 transmitted? 5. What are the signs and symptoms of COVID-19 infection in humans? 6. How is COVID-19 diagnosed? 7. How is COVID-19 infection ... more
Accessed: 24.03.2020

Chinese Guideline of Diagnosis and treatment of COVID-19

B. Cao China-Japan Friendship Hospital; World Health Organization (WHO); CAP-China; et al. (2020) C2
(7th Version) 20, March 2020
The information contained in this document, be it guidelines, recommendations, diagnostic algorithms or treatment regimens, are offered in this document in the public interest. To the best of the knowledge of the guideline writing team, the information contained in these guidelines is correct. Imple ... more
Временное руководство 19 марта 2020 г. Данный документ предоставляет временное руководство лабораториям и заинтересованным сторонам, участвующим в лабораторном ... more
Intensive Care Med (2009) 35:9–29DOI 10.1007/s00134-008-1336-9 Although thousands of papers have been devoted tohospital-acquired pneumonia (HAP), many controversiesremain, and management of HAP is probably often sub-optimal. Several reviews or guidelines have been pub-lished rec ... more
The international community sits at the tipping pointof a post-­‐antibiotic era, where common bacterial infections are no longer treatable with the antibiotic armamentarium that exists. In South Africa, t ... more

PACK On-site Training Resources COVID-19

Western Cape Government (health); Practical Approach to Care Kit (PACK); University of Cape Town; Knowledge Translation Unit (University of Cape Tow Lung Institute) Western Cape Government (health); Practical Approach to Care Kit (PACK); University of Cape Town; Knowledge Translation Unit (University of Cape Tow Lung Institute) (2020) C2
Primary Care Guide for the Adult· 2020 Western Cape Edition 20 March 2020