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WHO guidelines on management of Taenia solium neurocysticercosis

World Health Organization WHO (2021) C_WHO

The internationally recognized criteria for diagnosis of neurocysticercosis include a requirement for neuroimaging techniques, such as computerized tomography (CT) and/or magnetic resonance imaging (MRI), ideally supported by serology. These facilities are not available in all settings, especially i... more

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Dracunculiasis

Rawla, P.; Jan, A. National Library of Medicine (2022) CC

Dracunculiasis, also known as Guinea-worm disease is a parasitic disease caused by the nematode Dracunculus medinensis. The infection is transmitted to humans by drinking water contaminated with the small crustacean copepods (Cyclops) which contain the larvae of D. medinensis. Humans are the princip... more

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Surveillance data for human leishmaniasis indicate the need for a sustainable action plan for its management and control, Greece, 2004 to 2018

Tzani M., Barrasa, A., Vakali, A. et al. Euro Surveillance (2020) CC

Leishmaniasis is a parasitic disease caused by intracellular protozoan parasites of the genus Leishmania (Trypanosomatidae family); it is endemic in more than 98 countries worldwide [1]. Visceral (VL) and cutaneous (CL) leishmaniasis are the most common forms of the disease. VL causes a systemic dis... more

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Exploring the cultural effects of gender on perceptions of cutaneous leishmaniasis: a systematic literature review

Wenning, B., Price, H., Nuwangi, H. et al. Global Health Research and Policy (2022) CC

More than one million people each year become infected by parasites that cause the disease cutaneous leishmaniasis (CL). This disease manifests as one or more skin lesions or ulcers that are slow to heal with variable response rates to drug treatments. Thus far, little attention has been paid to how... more

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Cutaneous Leishmaniasis: Urgent need to develop more effective and user-friendly point-of-care diagnostic tools

DNDi redeLEISH (2022) CC

Leishmaniasis is a complex vector-borne disease involving in its transmission several species of protozoan parasites called Leishmania, a wide variety of animal reservoirs and phlebotomine sandflies vectors. Cutaneous Leishmaniasis (CL) is the most common form of the disease, and its clinical manife... more

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Leishmaniasis Treatment Market Size, Share, Industry Growth, Trend, Business Opportunities, Challenges, Drivers and Restraint Research Report by 2028

Reports and Data BioSpace (2022) C1

High prevalence of target diseases in rural and developing nations, increased prevalence of malnutrition across the globe, lack of hygiene and poor sanitation facilities, Migratory patterns of population, introduction of new chemical entity in the field of therapeutics, favorable government regulati... more

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Report of the first WHO stakeholders meeting on rhodesiense human African trypanosomiasis Geneva, 20–22 October 2014

World Health Organization WHO (2014) C_WHO

The objectives of the meeting were: 1. To update the current status of the disease transmission, country capacities and plans for tackling the disease. 2. To understand the epidemiology including disease distribution and risk, the models for estimating under-detection, the geographical variati... more

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Acute schistosomiasis, a diagnostic and therapeutic challenge

Jauréguiberry S., Paris L., Caumes E. (2010) C2

Clin Microbiol Infect 2010; 16: 225–231 Abstract In non-endemic countries, acute (invasive) schistosomiasis (AS) is typically seen in non-immune travellers, whereas chronic schistosomiasis is more frequently diagnosed in immigrants. Travellers with AS initially present with non-specific signs such... more

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Compendium of Animal Rabies Prevention and Control, 2016

Brown C.M., Slavinski S., Ettestad P. et al National Association of State Public Health Veterinarians Compendium of Animal Rabies Prevention and Control Committee (2016) C2

Rabies is a fatal viral zoonosis and serious public health problem.1 All mammals are believed to be susceptible to the disease, and for the purposes of this document, use of the term animal refers to mammals. The disease is an acute, progressive encephalitis caused by viruses in the genus Lyssavirus... more

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Capacity‐building for health workers dealing with leishmaniasis

World Health Organization WHO (2023) C_WHO

Website last accessed on 18.03.2023 WHO often receives requests from Member States and implementing partners to provide training in capacity‐building in endemic areas in order to better equip health personnel to diagnose, treat and control the disease.

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Control and surveillance of human African trypanosomiasis: report of a WHO Expert Committee

World Health Organization WHO (2013) C_WHO

The previous report of the WHO Expert Committee on this disease followed a meeting in 1995. Intensive, coordinated efforts against HAT during the intervening 18 years have resulted in a decrease in incidence to a point at which elimination is considered feasible. This report provides informati... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Echinococcosis - Arabic version

World Health Organization WHO (2023) C_WHO

Website last accessed on 09.04.2023 Human echinococcosis is a parasitic disease caused by tapeworms of the genus Echinococcus. More than one million people are affected by echinococcosis.

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Education, Communication, and Lots of Creativity: A Good Combination to Face Complex Problems Like Chagas

Social Innovations Journal (2023) C2

Website last accessed on 10.04.2023 The Chagas disease is frequently referred to as the effects that the parasite Trypanosoma cruzi (T. cruzi) has on people’s health. However, from our perspective, Chagas is much more than that: it is a complex socioenvironmental health problem in which elemen... more

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Elimination of soil-transmitted helminthiasis infection in Bangladesh: Knowledge, attitudes, and practices regarding mass drug administration

Tilak C.N., Retna S.P., Mohammad S.A. et al (2018) C2

Background: Despite several cycles of Mass Drug Administration (MDA), however, the prevalence of Soil-transmitted helminthiasis (STH) remains high in Bangladesh. A clear understanding of local knowledge, attitudes, and practices (KAP) related to the acceptance and utilization of MDA is critical for ... more

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Soil-transmitted helminth infections - Key Facts

World Health Organization WHO (2023) CC

Soil-transmitted helminth (STH) infections are among the most common infections worldwide with an estimated 1.5 billion infected people or 24% of the world’s population. These infections affect the poorest and most deprived communities with poor access to clean water, sanitation and hygiene in tro... more

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First Colombian consensus on congenital Chagas and clinical approach for women of child-bearing age diagnosed with Chagas

Cucunubá Z.M., Valencia-Hernándeza C.A. , Puerta C.J. et al (2017) C2

Congenital transmission of Chagas disease has not been extensively studied in Colombia, and there are no standardized processes in the health system regarding the specific diagnosis, treatment and follow-up of this disease. To generate recommendations on congenital Chagas disease and Chagas in wom... more

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How smartphones are fighting rabies in Africa

Edd McCracken University of Edinburgh (2023) C2

Website last accessed on 08.05.2023 Parts of the continent are still blighted by one of the world's deadliest diseases. An app is helping to turn the tide.

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Kala-azar Situation in Bangladesh - ppt video online download

Sohel Shomik, M. Jeremy Vernon Hancock (2023) C2

Website last accessed on 14.05.2023 Leishmaniasis A group of diseases, caused by the Leishmania parasites and transmitted by the sandfly

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Keeping the vector out: housing improvements for vector control and sustainable development

Kraef, C.; Röbbel, N. World Health Organization WHO (2017) C_WHO

Vector-borne diseases are responsible for 17% of the global burden of communicable diseases and more than 500 000 deaths annually. The ambitious global targets for the control of vector-borne diseases come in the context of the (re-)emergence of diseases, increasing resistances to insecticides and u... more