Bulletin of the World Health Organization, 2000, 78 (6)
Supplement Article
J Acquir Immune Defic Syndr Volume 78, Supplement 1, August 15, 2018 www.jaids.com
Mental health problems represent the greatest global burden of disease among children and adolescents. There is, however, lack of policy development and implementation for child and adolescent mental health (CAMH), particularly in low- and middle-income countries (LMICs) where children and adolescen...ts represent up to 50% of populations. South Africa, an upper-middle income country is often regarded as advanced in health and social policy-making and implementation in comparison to other LMICs. It is, however, not clear whether this is the case for CAMH.
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BMJ Global Health Vol.4 (2019 no.4
The Drug Resistance Index (DRI) is proposed as measure of antibiotic effectiveness in a given country, by combining, in a single metric the use of various antibiotic groups and the resistance proportions of several pathogens.It is a complicated measure that gives ...results that cannot be understood by common knowledge and logic. The DRI conveys a wrong message.
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A Spanish-translated clinical algorithm for management of suspected SARS-CoV-2 infection in pregnant women
Published:April 09, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30285-1
The Lancet Infectious Diseases
This Special Collection includes Cochrane Reviews on the following topics: medication; behavioural support; and gradual quitting. Interventions that mimic the act of smoking, notably e-cigarettes, have been excluded from this collection as the risks associated with their use in relation to the curre...nt pandemic are not clear. Cochrane Tobacco Addiction are working to remain up to date on all the relevant information, to provide support to people attempting to stop smoking during this difficult time.
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Cette collection spéciale comprend des revues Cochrane sur les sujets suivants : les médicaments, le soutien comportemental et le sevrage tabagique progressif. Les interventions qui imitent l'acte de fumer, notamment les cigarettes électroniques, ont été exclues de cette collection car les risq...ues associés à leur utilisation en relation avec la pandémie actuelle ne sont pas clairs. Le Groupe Cochrane sur le Tabagisme travaille pour rester à jour sur toutes les informations pertinentes, afin d'apporter un soutien aux personnes qui tentent d'arrêter de fumer pendant cette période difficile.
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این مجموعه ویژه شامل مرورهای کاکرین در موضوعات زیر است: دارو، پشتیبانی رفتاری، و ترک تدریجی. مداخلاتی که عمل سیگار کشیدن را تقلید میکنند، بهویژه سیگارهای الکترون...یکی، بهعلت اینکه خطر مرتبط با استفاده از آنها در همهگیری اخیر واضح نیست؛ از این مجموعه خارج شدهاند. گروه اعتیاد به دخانیات کاکرین در حال کار هستند تا همه اطلاعات مرتبط را به منظور ارائه پشتیبانی به افرادی که در این زمان سخت در تلاش برای ترک سیگار هستند؛ بهروز نگهدارند.
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Koleksi Istimewa ini termasuk Ulasan Cochrane mengenai topik berikut: ubat-ubatan; sokongan tingkah laku; dan berhenti secara beransur-ansur. Intervensi yang meniru tindakan merokok, terutamanya e-rokok, telah dikecualikan daripada koleksi ini kerana risiko yang berkaitan dengan penggunaannya berhub...ung dengan pandemik semasa tidak jelas. Ketergantungan Tembakau Cochrane sedang berusaha untuk terus kemaskini pada semua maklumat yang berkaitan, untuk memberikan sokongan kepada orang yang cuba berhenti merokok dalam masa yang sukar ini.
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Diese Sonderkollektion enthält Cochrane Reviews zu den folgenden Themen: Medikamente; Verhaltensunterstützung; und allmähliches Aufhören. Interventionen, die den Vorgang des Rauchens imitieren, insbesondere E-Zigaretten, wurden von dieser Sonderkollektion ausgeschlossen, da die Risiken ihrer Ver...wendung vor dem Hintergrund der aktuellen Pandemie unklar sind. Cochrane Tobacco Addiction arbeitet daran, zu allen relevanten Informationen auf dem aktuellen Stand zu bleiben, um Menschen, die während dieser schwierigen Zeit mit dem Rauchen aufhören wollen, Unterstützung zu bieten.
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Esta Coleção Especial inclui Revisões Cochrane sobre os seguintes tópicos: medicação; apoio comportamental; e desistência gradual. As intervenções que imitam o ato de fumar, especialmente os cigarros electrónicos, foram excluídas desta coleção uma vez que os riscos associados ao seu uso... em relação à atual pandemia não são claros. O grupo Cochrane Tobacco Addiction está trabalhando para se manter atualizado com todas as informações relevantes, para apoiar as pessoas que tentam parar de fumar durante este período difícil.
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Эта Специальная Коллекция включает Кокрейновские обзоры по следующим темам: лекарственное лечение, поведенческая поддержка и постепенный отказ от курения. Вмеша...ельства, имитирующие акт курения, в частности, электронные сигареты, были исключены из этой коллекции, поскольку риски, связанные с их использованием в связи с текущей пандемией, не ясны. Кокрейновская группа по табачной зависимости работает над тем, чтобы вся соответствующая информация была актуальна (обновлена), чтобы обеспечить поддержку людям, пытающимся бросить курить в это трудное время.
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La colección incluye revisiones Cochrane sobre los siguientes temas: medicamentos; apoyo conductual; y abandono gradual. Las intervenciones que imitan el acto de fumar, especialmente los cigarrillos electrónicos, se han excluido de esta colección ya que los riesgos asociados a su uso en relación... con la pandemia actual no están claros. El Grupo Cochrane de Adicción al Tabaco está trabajando para mantenerse al día con toda la información relevante y brindar apoyo a las personas que intentan dejar de fumar durante este momento difícil.
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Chronic manifestations of Chagas disease present as disabling and life-threatening conditions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mechanisms underlying Trypanosoma cruzi’s infection and the host-parasit...e interactions that follow, prompt diagnosis and treatment remain a challenge, particularly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence
factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
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The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients wit...h DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.
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Information on the causes of cancer at specific sites is important to cancer control planners, cancer researchers, cancer patients, and the general public. The International Agency for Research on Cancer (IARC) Monograph series, which has classified human carcinogens for more than 40 years, recently... completed a review to provide up-to-date information on the cancer sites associated with more than 100 carcinogenic agents. Based on IARC’s review, we listed the cancer sites associated with each agent and then rearranged this information to list the known and suspected causes of cancer at each site. We also summarized the rationale for classifications that were based on mechanistic data. This information, based on the forthcoming IARC Monographs Volume 100, offers insights into the current state-of-the-science of carcinogen identification. Use of mechanistic data to identify carcinogens is increasing, and epidemiological research is identifying additional carcinogens and cancer sites or confirming carcinogenic potential under conditions of lower exposure. Nevertheless, some common human cancers still have few (or no) identified causal agents.
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While epidemiological data for type 1 diabetes (T1D) in low/middle-income countries, and particularly low-income countries (LICs) including Liberia is lacking, prevalence in LICs is thought to be increasing. T1D care in LICs is often impacted by challenges in diagnosis and management. These challeng...es, including misdiagnosis and access to insulin, can affect T1D outcomes and frequency of severe complications. Despite the severe nature of T1D and growing burden in subSaharan Africa, little is currently known about the impact of T1D on patients and caregivers in the region. Methods We conducted a qualitative study consisting of interviews with patients with T1D, caregivers, providers, civil society members and a policy-maker in Liberia to better understand the psychosocial and economic impact of living with T1D, knowledge of T1D and selfmanagement, and barriers and facilitators for accessing T1D care.
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The article outlines the prioritized research agenda for the prevention and control of chronic respiratory diseases (CRDs) as part of the World Health Organization's (WHO) action plan on noncommunicable diseases (NCDs) from 2008 to 2013. It highlights the significant global impact of CRDs, including... asthma, chronic obstructive pulmonary disease (COPD), and other related conditions, particularly in low- and middle-income countries (LMICs). The document stresses the need for effective prevention strategies and better surveillance, as well as enhanced healthcare infrastructure and resources in LMICs. It calls for research into CRD risk factors, effective interventions, and integrated care approaches that align with broader NCD prevention programs. The article emphasizes the importance of public health initiatives and cross-sector collaborations to reduce the disease burden and improve patient outcomes.
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