HIV Diagnostics
Information Note
WHO/HIV/2017.16
Following review of the latest evidence, WHO recommends that TB-LAMP can be used as a replacement for microscopy for the diagnosis of pulmonary TB in adults with signs and symptoms of TB. It can also be considered as a follow-on test to microscopy in adults with signs and symptoms of pulmonary TB, e...specially when further testing of sputum smear-negative specimens is necessary.
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This algorithm is addressed to laboratories
with established capacity(molecular, antigenic and/orserological) to detect dengue (DENV), Zika (ZIKV), and chikungunya(CHIKV) as part of the differential diagnosis for arborviruses. A BSL2 containment level is required to handle suspected samples.
This document aims to present an algorithm for deciding whom to test and provide guidance on the laboratory tests for Zika virus infection diagnosis in order to support clinical diagnostic and case reporting through surveillance among EU Member States. The algorithm is not intended for clinical man...agement of patients with suspected Zika virus infection.
The information is provisional and subject to revision when new information becomes available.
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Copenhagen, Denmark, 24–25 August 2017
This guide is intended for use by mentors of nurses, midwives, doctors and other health care workers providing HEID services. Large File 18 MB
PLOS Medicine | DOI:10.1371/journal.pmed.1002088 August 23, 2016
Outline
• Welcome and objectives
• Microbiology, epidemiology and clinical presentation
• Surveillance for imported cases including case definitions
• Laboratory diagnosis • Infection prevention and hospital readiness
• Patient flow and actions required at each step
• Co-ord...inating a public health response
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Check back here for updates on COVID-19 diagnosis and treatment
Slideset updated regularly to reflect the state of the COVID-19 pandemic and to include the latest data and guidance on best practices for diagnosis and management; topics include global epidemiology, screening and diagnosis, natural history and clinical presentation, disease severity, medical manag...ement, and treatment options.
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This Rapid Communication aims to inform national TB programmes and other stakeholders about the key implications of the latest evidence on the use of specific molecular assays as initial diagnostic tests of pulmonary and extrapulmonary TB and RR-TB, in adults and children.
A elaboração das Diretrizes para Diagnóstico e Tratamento da COVID-19 é uma resposta rápida ao enfrentamento da COVID-19, diante da declaração de pandemia pela Organização Mundial de Saúde (OMS) e das iniciativas do Ministério da Saúde para enfrentamento dessa nova situação no Brasil. ...
A intensa produção de evidência sobre o assunto nos últimos meses faz destas Diretrizes um documento dinâmico que terá versões provisórias e atualizações periódicas, acompanhando a produção de novas evidências para assim estabelecer recomendações.
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In the Region of the Americas, the leishmaniases are a group of diseases caused by various species of Leishmania, which cause a set of clinical syndromes in infected humans that can involve the skin, mucosa, and visceral organs. The spectrum of clinical disease is varied and depends on the interacti...on of several factors related to the parasite, the vector, and the host. Cutaneous leishmaniasis is the form most frequently reported in the Region and nearly 90% of cases present single or multiple localized lesions. Other cutaneous clinical forms, such as disseminated and diffuse cutaneous leishmaniasis, are more difficult to treat and relapses are common. The mucosal form is serious because it can cause disfigurement and severe disability if not diagnosed and treated early on. Visceral leishmaniasis is the most severe form, as it can cause death in up to 90% of untreated people.
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In 2009, WHO’s Second International Conference on Buruli Ulcer Control and Research resolved to strengthen the capacity of national laboratories to confirm cases of the disease, but advised that “efforts are still needed to develop simple diagnostic tools usable in the field as well as disabilit...y prevention methods”.
In 2013, WHO and the Foundation for Innovative New Diagnostics convened a meeting of Buruli ulcer experts in Geneva, Switzerland (9) at which two priority unmet needs in diagnosis were identified:
a diagnostic test for early detection of Buruli ulcer in symptomatic patients with sufficient positive predictive value to put patients on appropriate treatment; and
a screening test at the primary health care or community level for symptomatic patients with ulcer
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The Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations outline a public health response for 5 key populations (men who have sex with men, trans and gender diverse people, sex workers, people who inject drugs and people in prisons and... other closed settings). They present and discuss new recommendations and consolidate a range of recommendations and guidance from current WHO guidelines.
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