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Global Advisory Committee on Vaccine Safety, 5–6 June 2019

World Health Organization WHO (2019) C_WHO

The Committee examined the clinical development of Ebola virus vaccines and conducted an inventory of available data on their safety. It also reviewed 3 generic issues: updating a global strategy on vaccine safety, use of a network of distributed data ... more

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CONSENSUS DOCUMENT FOR MANAGEMENT OF GALLBLADDER CANCER

Indian Council of Medical Research (ICMR) (2014) C1

Prepared as an outcome of ICMR Subcommittee on Gastric Cancer | This consensus document on Management of Gallbladder cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also ... more

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Eradicating Polio in Afghanistan and Pakistan

April Chang, Edgar Chavez, Sadika Hameed et al. Center for Strategic and International Studies (CSIS) (2012) CC

Through 2004, reports showed that polio incidence in Afghanistan was in decline. When the Global Polio Eradication Initiative (GPEI) reported only 30 new cases in 2010, the program was widely hailed as effective and on the road to complete success. However, GPEI and the Afghan Ministry of Health rep... more

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A situational analysis of programmatic management of TB preventive treatment in the WHO South-East Asia Region

World Health Organization WHO (2020) C_WHO

Tuberculosis (TB) prevention is essential for reaching the End TB targets in the South-East Asia Region (SEAR) of World Health Organization (WHO)1. The targets of 80% reduction in TB incidence rate and 90% reduction in TB mortality by 2030 (compared to 2015 levels) can be achieved only with addition... more

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Understanding modelling approaches for sexual, reproductive, maternal, newborn, child and adolescent health, and nutrition

World Health Organization WHO; UNICEF and UNFPA (2021) C_WHO

Modelling the health impacts of disruptions to essential health services during COVID-19 Module 1 Several epidemiological models have been created to assess the potential impact of disruptions to essential health services caused by COVID-19 on morbidity and mortality from conditions other than COVI... more

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Burden of Severe Fungal Infections in Burkina Faso

Bamba S. , Zida A., Sangaré I. et al. Journal of Fungi (2018) CC

Because of the limited access to more powerful diagnostic tools, there is a paucity of data regarding the burden of fungal infections in Burkina Faso. The aim of this study was to estimate the incidence and prevalence of serious fungal infections in this sub-Saharan country. We primarily used the na... more

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Malaria vaccine: WHO position paper - March 2022
recommended

World Health Organization WHO (2022) C_WHO

Weekly Epidemiological Record No 9, 2022, 97, 61–80 This position paper supersedes the 2016 publication, “Malaria vaccine: WHO position paper-2016.”1 It includes the updated WHO recommendations on the wider use of the RTS,S/AS01 vaccine for the reduction of malaria morbidity and mortality in ... more

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Use of a Participatory Method for Community-Based Brucellosis Control Design in Agro-Pastoral Areas in Tanzania

Asakura S.; Makingi G.; John K. et al. Frontiers in Veterinary Science (2022) CC

Brucellosis is widespread in both humans and livestock in many developing countries. The authors have performed a series of epidemiological studies on brucellosis in agro-pastoral areas in Tanzania since 2015, with the aim of the disease control. Previously, the potential of a community-based brucel... more

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Using recency assays for HIV surveillance: 2022 technical guidance

World Health Organization WHO (2022) C_WHO

Recency assays use one or more biomarkers to identify whether HIV infection in a person is recent (usually within a year or less) or longstanding. Recency assays have been used to estimate incidence in representative cross-sectional surveys and in epidemiological studies to better understand the pat... more

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Discrete typing units of Trypanosoma cruzi: Geographical and biological distribution in the Americas

Veláquez-Ortiz, N.; Herrera, G.; Hernández, C. et al. Scientific Data (2022) CC

Chagas disease caused by Trypanosoma cruzi is a public health issue in Latin America. This highly diverse parasite is divided into at least seven discrete typing units (DTUs) TcI-TcVI and Tcbat. Some DTUs have been associated with geographical distribution in epidemiological scenarios and clinical m... more

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Infection prevention and control in the context of coronavirus disease (‎COVID-19)‎: a living guideline, 13 January 2023

World Health Organisation (WHO) (2023) C_WHO

The WHO continuously reviews available data on SARS-CoV-2 variants of concern. For this version, the global epidemiological situation of the COVID-19 pandemic as of 21 January 2022 – at a time when the Omicron VOC had been identified in 171 countries across all six WHO Regions and was rapidly re... more

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Eco-epidemiological studies to develop integrated vector surveillance of leishmaniasis vectors in the Americas

Salomón, O.; Quintana, M. One Health and Implementation Research (2022) CC

We developed an integrated vector surveillance (IVS) proposal for cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL) in the Americas, based on eco-epidemiological studies conducted by researchers of the Leishmaniasis Research Network of Argentina. For CL, the transmission was explained in ... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Cardiac arrhythmias in low- and middle-income countries

Mkoko, P.; Bahiru, E.; Ajijola, O.A. et al. Cardiovascular Diagnosis and Therapy (2019) CC

Many low- and middle-income countries (LMICs) are undergoing an epidemiological transition. With an improvement in socioeconomic conditions and an aging population, cardiovascular diseases (CVDs), like cardiac arrhythmias, are expected to increase in these countries. However, there are limited studi... more

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Heart failure in low-income and middle-income countries: failing REPORT card grades

Naik, N.; Narula, J. The Lancet Global Health (2020) CC

Heart failure is an important global health problem, and the associated public health and economic effect is increasing across all societies and geographies. Epidemiological studies have estimated that there are more than 25 million patients with heart failure globally, and population-based studie... more

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IDF Guide for Epidemiology Studies

International Diabetes Federation (2021) CC

The IDF Guide for Diabetes Epidemiology Studies has been developed to create standardized epidemiological methods in diabetes studies to enable researchers to conduct high-quality studies that generate robust data

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Childhood Asthma: Low and Middle-Income Countries Perspective

Soto-Martínez, M.E.; Soto-Quiros, M.E.; Custovic, A. Acta Medica Academica (2020) CC

Our aim is to review current asthma epidemiology, achievements from the last 10 years, and persistent challenges of asthma man- agement and control in low-middle income countries (LMICs). Despite global efforts, asthma continues to be an important public health problem worldwide, particularly in poo... more

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Assessing the nature of asthma in African epidemiological studies: a scoping review protocol

Ndlovu, V.; Chimbari, M.J.; Sibanda, E. (2020) CC2

Asthma is one of the most common chronic respiratory conditions in the world and is increasing in prevalence, particularly in Africa and other low-income countries. The disproportionately high numbers of premature deaths and severe or uncontrolled cases in many African countries are indicative of th... more

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Identifying asthma in population studies: from single entity to a multi-component approach

Marks, G. B. (2005) CC2

Considerable energy has been expended over the last two decades in developing methods for identifying the presence of asthma among participants in population studies. The objective of this endeavour has commonly been to enable epidemiological research on risk factors for asthma, with the ultimate ai... more

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Assessing the nature of asthma in African epidemiological studies: a scoping review protocol 2020

Ndlovu, V.; Chimbari, M.J.; Sibanda, E. (2020) CC2

Malaria vaccine: WHO position paper - March 2022 recommended

Malaria vaccine: WHO position paper - March 2022
recommended