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HEARTS. Tool for the development of a consensus protocol for treatment of hypertension

World Health Organization WHO, et al. (2018) C_WHO
Technical package for cardiovascular disease management in primary health care.
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Revised Common Protocol for Uniform Evaluation of Public Health Pesticides including Bio-larvicides for use in Vector Control

Indian Council of Medical Research (ICMR); National Vector Borne Disease Control Programme (NVBDCP); National Centre for Disease Control (NCDC) (2014) C1
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Impact of WASH Interventions during Disease Outbreaks in Humanitarian Emergencies: A systematic review protocol
recommended

Tufts University, Oxfam (2016) CC
In this review, the editors will investigate the impact of eight WASH interventions in preventing (reducing the risk of) and controlling outbreaks in LMIC, with particular focus on three diseases of current concern to the response community – cholera, Ebola, and Hepatitis E. Additionally, we will ... more
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Surface sampling of coronavirus disease (COVID-19): A practical “how to” protocol for health care and public health professionals

World Health Organization WHO (2020) C_WHO
The role of environmental contamination in transmission of COVID-19 virus is currently not clear. This protocol has been designed to determine (viable) virus presence and persistence on fomites in various locations where a patient infected with COVID-19 is currently receiving care or being isolated,... more
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Action Protocol for Enhanced SARI and ILI Surveillance for COVID-19 in Africa (Arabic)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C2
March 2020 The number of African Union Member States reporting COVID- 19 cases is increasing and there is a likelihood of community transmission. The WHO recently modified the COVID-19 suspect case definition to include severe acute respiratory infection and advises testing of all severe acute r... more
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Action Protocol for Enhanced SARI and ILI Surveillance for COVID-19 in Africa

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C2
March 2020 The number of African Union Member States reporting COVID- 19 cases is increasing and there is a likelihood of community transmission. The WHO recently modified the COVID-19 suspect case definition to include severe acute respiratory infection and advises testing of all severe acute res... more
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Assessment of risk factors for coronavirus disease 2019 (COVID-19) in health workers: protocol for a case-control study

World Health Organization WHO (2020) C_WHO
Nested case-control study of health workers exposed to confirmed COVID-19 patients. Similar objectives to the cohort study but case-control studies may be cheaper and provide robust evidence to characterize and assess the risk factors for SARS-CoV-2 infection in health workers exposed to COVID-19 p... more
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Generic protocol for a population-based, age- and gender- stratified sero-survey study for SARS-CoV-2

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
The number of confirmed COVID-19 cases detected and reported in each country is influenced by many factors including limited access and/or utilization of healthcare and COVID-19 testing, limited surveillance, lack of knowledge amongst the population about when to seek testing, an asymptomatic pres... more
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Guidelines for COVID-19 testing and quarantine of air travellers - Addendum to the Aviation Health Safety Protocol

European Centre for Disease Prevention and Control ECDC (2020) CC
This joint ECDC-European Union Aviation Safety Agency (EASA) document aims to support Member States in determining a coordinated approach to reduce the risks related to the movement of people by air within and between the EU/EEA countries and the UK in the context of the COVID-19 pandemic, noting th... more
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Protocol to investigate non-seasonal influenza and other emerging acute respiratory diseases

World Health Organization WHO (2018) C_WHO
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Clinical guidelines - Diagnosis and treatment manual Chapter 6: Parasitic diseases

MSF, Dubois, G.; Vasseur-Binachon, B.; Yoshimoto, C. Médecins Sans Frontières (2022) CC
Chapter 6 contents Malaria Human African trypanosomiasis (sleeping sickness) American trypanosomiasis (Chagas disease) Leishmaniases Intestinal protozoan infections (parasitic diarrhoea) Flukes Schistosomiases Cestodes Nematode infections Filariasis ... more
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Acute Chagas Disease: New Global Challenges for an Old Neglected Disease

Andrade, D.; Gollob, K.; Dutra, W. PLoS Neglected Tropical diseases (2015) CC
Abstract: Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health. A plethora of information concerning the chronic phase of human Chaga... more
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Review Challenges in Chagas Disease Drug Development

Francisco, A.; Jayawardhana, S.; Olmo, F. et al. Molecules MDPI (2020) CC
The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public health problem throughout Latin America. Current therapeutic options are characterised by limited efficacy, long treatment regimens and frequent toxic side-effects. Advances in this area have been compromised by gaps... more
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Chagas Disease in Dogs: Transmission, Diagnosis, Treatment, and Prevention

Saunders, A. & Hamer, S. Today's Veterinary Practice (2020) CC
Chagas disease is caused by Trypanosoma cruzi, a protozoal organism primarily transmitted by triatomine insect vectors, also known as “kissing bugs.” It is a zoonotic disease originally described by Brazilian physician Dr. Carlos Chagas in 1909 and is widespread in Latin America. Although triato... more
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Chagas Disease: Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV

Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV Clinical Info HIV (2018) CC
Epidemiology Chagas disease (American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi, and transmitted to humans by infected triatomine bugs, and less commonly by transfusion, organ transplant, from mother to infant, and in rare instances, by ingestion of contaminated food or... more
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American trypanosomiasis (Chagas disease)

MSF medical guidelines (2019) CC
Chagas disease is a zoonosis caused by the protozoa Trypanosoma cruzi. It is transmitted to humans by contact of triatomine bug faeces with a break in the skin (often caused by a bite from the triatomine bug), or with mucous membranes. Transmission by contaminated blood transfusion, accidental expos... more
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Clinical utlity of peptide microarrys in the serodiagnosis of neglected tropical diseases in sub-Saharan Africa: protocol for a diagnostic test accuracy sytematic review

Vengesai A., Naicker T., Kasambala M., et al. BMJ Open (2021) C2
Neglected tropical diseases tend to cluster in the same poor populations, and to make progress with their control, they will have to be dealt with in an integrated manner. Peptide microarrays may be a solution to tese problems, where diagnosis for co-infection can be detected simultaneously using th... more
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Chagas heart disease: An overview of diagnosis, manifestations, treatment, and care

Saraiva R.M., Mediano M.F.F., Mendes F.S. et al World Journal of Cardiology (WJC) (2021) C2
Chagas heart disease (CHD) affects approximately 30% of patients chronically infected with the protozoa Trypanosoma cruzi. CHD is classified into four stages of increasing severity according to electrocardiographic, echocardiographic, and clinical criteria. CHD presents with a myriad of clinical man... more
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Drug discovery for chagas disease: A viewpoint

Kratz J.M. Elsevier (2019) C2
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. It is a significant public health problem, affecting millions of people worldwide. And although it was described 110 years ago, only two old nitroheterocyclic drugs, benznidazole and nifurtimox, are cu... more
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Assessing the nature of asthma in African epidemiological studies: a scoping review protocol

Ndlovu, V.; Chimbari, M.J.; Sibanda, E. (2020) CC2
Asthma is one of the most common chronic respiratory conditions in the world and is increasing in prevalence, particularly in Africa and other low-income countries. The disproportionately high numbers of premature deaths and severe or uncontrolled cases in many African countries are indicative of th... more