This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita...ls in the Democratic Republic of the Congo between August 2005 and September 2009 to support the registration of pafuramidine for treatment of first stage HAT in collaboration with the United States Food and Drug Administration. Patients were treated with either 100 mg of pafuramidine orally twice a day for 10 days or 4 mg/kg pentamidine intramuscularly once daily for 7 days to assess the efficacy and safety of pafuramidine versus pentamidine. Pregnant and lactating women as well as adolescents were included.
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Water, Sanitation and Hygiene (WASH) in Southern Africa
• The impact of the drought in Southern Africa on WASH is already observed in places where the drought has been more acute and where WASH coverage was already low.
• Only 61 per cent of the region’s population has access to safe... drinking water and 39 per cent have access to adequate sanitation facilities.
• Approximately 6.4 million people (including 3.2 million children) in the seven priority countries have reduced access to safe water as a direct result of the El Niño drought.
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Want to build a tippy tap? Want to teach someone else how to? Here is a graphical manual that works for both literate and illiterate populations. If you need a particular language that’s not here or can assist with translation, please go to the website http://www.tippytap.org/build-a-tippy-tap-...manual
Axxessed 18 December 2014
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