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Ensuring sustainable access to effective antibiotics for EVERYONE - EVERYWHERE

ReAct Action on Antibiotic Resistance (2021) CC

How to address the global crisis in antibiotic research and development. The report includes a comprehensive summary and critical evaluation of recent initiatives to overcome the barriers to achieve sustainable access to antibiotics. As antibiotic resistance will continue to develop as long as we depend on these medicines to treat bacterial infections, a continuous supply of new effective antibiotics is needed. The report identifies five key challenges that must be solved in order to achieve sustainable access for all, and charts out options for governmental action in response to each of them

Tags: AMR, antibiotics, resistance, antibiotic resistance, Antimicrobial resistance, Access,

Source: https://www.reactgroup.org/wp-content/up

Strengthening multisectoral coordination on antimicrobial resistance: a landscape analysis of efforts in 11 countries

Joshi, M.P.; et al. (2021) CC

J of Pharm Policy and Pract 14, 27 (2021). https://doi.org/10.1186/s40545-021-00309-8

Tags: AMR, Antimicrobial resistance, Analysis, strategy,

Source: https://joppp.biomedcentral.com/articles

High global consumption of potentially inappropriate fixed dose combination antibiotics: Analysis of data from 75 countries

Bortone, B.; et al. (2021) CC

PlosOne January 20, 2021 https://doi.org/10.1371/journal.pone.0241899 Antibiotic fixed dose combinations (FDCs) can have clinical advantages such as improving effectiveness and adherence to therapy. However, high use of potentially inappropriate FDCs has been reported, with implications for antimicrobial resistance (AMR) and toxicity

Tags: antibiotics, AMR, antibiotic resistance, study protocol, Antibiotic fixed dose combinations FDCs,

Source: https://journals.plos.org/plosone/articl

Young doctors’ perspectives on antibiotic use and resistance: a multinational and inter-specialty cross-sectional European Society of Clinical Microbiology and Infectious Diseases (ESCMID) survey

Beovic B., M. Dousak, C. Pulcini et al. Oxford University Press (2019) C2

Antibiotic resistance has been recognized as a major global health threat and optimizing prescribing is one of the most effective measures to preserve the effectiveness of antibiotics. The quality of prescribing depends mostly on those prescribers belonging to clinical medical specialties having direct contact with patients. These doctors, who comprise the majority of antibiotic prescribers,undergo long-term undergraduate and postgraduate training that shapes their professional knowledge and behaviour J Antimicrob Chemother2019;74: 3611–3618doi:10.1093/jac/dkz375 Advance Access publication 3 September 201

Tags: AMR, Antimicrobial resistance, infectious diseases, antibiotics, doctors,

Source: https://academic.oup.com/jac/article/74/

Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries

Hsia Y., B. R Lee, A. Versporten, et al The Lancet (2019) C2

Improving the quality of hospital antibiotic use is a major goal of WHO’s global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally. We aimed to present data on patterns of paediatric AWaRe antibiotic use that could be used for local and national stewardship interventions. www.thelancet.com/lancetgh Vol 7 July 201

Tags: AMR, Antimicrobial resistance, antibiotics, antibiotic stewardship,

Source: https://www.thelancet.com/action/showPdf

Prevalence and Antibiotic Resistance of Stenotrophomonas maltophilia in Respiratory Tract Samples: A 10-Year Epidemiological Snapshot

Gajda M., E. Urban (2019) CC

Stenotrophomonas maltophiliais a nonfermenting Gram-negative rod that is ubiquitous in nature (predominantly occurring in aquatic environments and on plants). Biochemically, it iscatalase positive and oxidase negative, and it produces acid frommaltose (hence the name“maltophilia”). Due to its chargedcell wall surface and biofilm production, it may attach to and survive on abiotic surfaces in clinical settings (eg, central venouscatheters, disinfectant and hand-washing solutions, solutions for hemodialysis, endoscopes, inspiration/expiration circuits of ventilators, nebulizers, tap water, and showerheads). Health Services Research and Managerial Epidemiology Volume 6: 1-9ªThe Author(s) 201

Tags: AMR, Antimicrobial resistance, antibiotics, Epidemiology,

Source: https://www.ncbi.nlm.nih.gov/pmc/article

Epidemiological Alert: Outbreaks of resistant microorganisms associated with medical tourism

Pan American Health Organization PAHO, World Health Organization WHO (2019) C_WHO

Given an increase in outbreaks caused by resistant microorganisms associated with medical tourism, the Pan American Health Organization / World Health Organization (PAHO/WHO) encourages Member States to strengthen their capacity to detect and manage infections caused by resistant microorganismsin patients who traveled outside of their country of residence to receive healthcare. Furthermore, PAHO/WHO stresses the importance to implement preventive measures to reduce healthcare-associated infections at all levels of the health system

Tags: AMR, Antimicrobial resistance, medical tourism, antibiotics,

Source: https://www.paho.org/hq/index.php?option

Antibacterial agents in preclinical development: an open access database

World Health Organization WHO (2019) C_WHO

The pre-clinical pipeline shows more innovation and diversity, with 252 agents being developed to treat WHO priority pathogens. However, these products are in the very early stages of development and still need to be proven effective and safe. The optimistic scenario, the report indicates, is for the first two to five products to become available in about 10 years

Tags: Antimicrobial resistance, research, antibacterial, pipeline, pharmaceutical industry, Pharmaceuticals, antibiotics,

Source: https://apps.who.int/iris/bitstream/hand

Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis

P. Collignon, J.J.Beggs, T.R. Walsh, et al. (2018) CC

The Lancet Planetary Health, Volume 2, ISSUE 9, Pe398-e405, September 01, 2018. Reduction of antibiotic consumption will not be sufficient to control antimicrobial resistance because contagion—the spread of resistant strains and resistance genes—seems to be the dominant contributing factor. Improving sanitation, increasing access to clean water, and ensuring good governance, as well as increasing public health-care expenditure and better regulating the private health sector are all necessary to reduce global antimicrobial resistance

Tags: antibiotic resistance, AMR, Anthropology, Socioeconomic context, socioeconomic factors, research, public health, Hygiene, WASH, Sanitation,

Source: https://www.thelancet.com/journals/lanpl

Pathways of antibiotic use in Bangladesh: qualitative protocol for the PAUSE study

Rousham E. K., M. Aminul Islam, P. Nahar et al. (2018) C2

Global actions to reduce antimicrobial resistance (AMR) include optimising the use of antimicrobial medicines in human and animal health. In countries with weak healthcare regulation, this requires a greater understanding of the drivers of antibiotic use from the perspective of providers and consumers. In Bangladesh, there is limited research on household decision-making and healthcare seeking in relation to antibiotic use and consumption for humans and livestock. Knowledge is similarly lacking on factors influencing the supply and demand for antibiotics among qualified and unqualified healthcare providers. The aim of this study is to conduct integrated research on household decision-making for healthcare and antibiotic use, as well as the awareness, behaviours and priorities of healthcare providers and sellers of antibiotics to translate into policy development and implementatio

Tags: AMR, Antimicrobial resistance, Bangladesh, antibiotics, bangladesh,

Source: https://www.ncbi.nlm.nih.gov/pmc/article

	Ensuring sustainable access to effective antibiotics for EVERYONE - EVERYWHERE ReAct Action on Antibiotic Resistance (2021) CC View PDF(3) Download (2) Add to my MEDBOX How to address the global crisis in antibiotic research and development. The report includes a comprehensive summary and critical evaluation of recent initiatives to overcome the barriers to achieve sustainable access to antibiotics. As antibiotic resistance will continue to develop as long as we depend on these medicines to treat bacterial infections, a continuous supply of new effective antibiotics is needed. The report identifies five key challenges that must be solved in order to achieve sustainable access for all, and charts out options for governmental action in response to each of them Tags: AMR, antibiotics, resistance, antibiotic resistance, Antimicrobial resistance, Access, Source: https://www.reactgroup.org/wp-content/up
	Strengthening multisectoral coordination on antimicrobial resistance: a landscape analysis of efforts in 11 countries Joshi, M.P.; et al. (2021) CC Open external link (96) Add to my MEDBOX J of Pharm Policy and Pract 14, 27 (2021). https://doi.org/10.1186/s40545-021-00309-8 Tags: AMR, Antimicrobial resistance, Analysis, strategy, Source: https://joppp.biomedcentral.com/articles
	High global consumption of potentially inappropriate fixed dose combination antibiotics: Analysis of data from 75 countries Bortone, B.; et al. (2021) CC View PDF(2) Download (2) Add to my MEDBOX PlosOne January 20, 2021 https://doi.org/10.1371/journal.pone.0241899 Antibiotic fixed dose combinations (FDCs) can have clinical advantages such as improving effectiveness and adherence to therapy. However, high use of potentially inappropriate FDCs has been reported, with implications for antimicrobial resistance (AMR) and toxicity Tags: antibiotics, AMR, antibiotic resistance, study protocol, Antibiotic fixed dose combinations FDCs, Source: https://journals.plos.org/plosone/articl
	Young doctors’ perspectives on antibiotic use and resistance: a multinational and inter-specialty cross-sectional European Society of Clinical Microbiology and Infectious Diseases (ESCMID) survey Beovic B., M. Dousak, C. Pulcini et al. Oxford University Press (2019) C2 Open external link (273) Add to my MEDBOX Antibiotic resistance has been recognized as a major global health threat and optimizing prescribing is one of the most effective measures to preserve the effectiveness of antibiotics. The quality of prescribing depends mostly on those prescribers belonging to clinical medical specialties having direct contact with patients. These doctors, who comprise the majority of antibiotic prescribers,undergo long-term undergraduate and postgraduate training that shapes their professional knowledge and behaviour J Antimicrob Chemother2019;74: 3611–3618doi:10.1093/jac/dkz375 Advance Access publication 3 September 201 Tags: AMR, Antimicrobial resistance, infectious diseases, antibiotics, doctors, Source: https://academic.oup.com/jac/article/74/
	Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries Hsia Y., B. R Lee, A. Versporten, et al The Lancet (2019) C2 Open external link (272) Add to my MEDBOX Improving the quality of hospital antibiotic use is a major goal of WHO’s global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally. We aimed to present data on patterns of paediatric AWaRe antibiotic use that could be used for local and national stewardship interventions. www.thelancet.com/lancetgh Vol 7 July 201 Tags: AMR, Antimicrobial resistance, antibiotics, antibiotic stewardship, Source: https://www.thelancet.com/action/showPdf
	Prevalence and Antibiotic Resistance of Stenotrophomonas maltophilia in Respiratory Tract Samples: A 10-Year Epidemiological Snapshot Gajda M., E. Urban (2019) CC Open external link (272) Add to my MEDBOX Stenotrophomonas maltophiliais a nonfermenting Gram-negative rod that is ubiquitous in nature (predominantly occurring in aquatic environments and on plants). Biochemically, it iscatalase positive and oxidase negative, and it produces acid frommaltose (hence the name“maltophilia”). Due to its chargedcell wall surface and biofilm production, it may attach to and survive on abiotic surfaces in clinical settings (eg, central venouscatheters, disinfectant and hand-washing solutions, solutions for hemodialysis, endoscopes, inspiration/expiration circuits of ventilators, nebulizers, tap water, and showerheads). Health Services Research and Managerial Epidemiology Volume 6: 1-9ªThe Author(s) 201 Tags: AMR, Antimicrobial resistance, antibiotics, Epidemiology, Source: https://www.ncbi.nlm.nih.gov/pmc/article
	Epidemiological Alert: Outbreaks of resistant microorganisms associated with medical tourism Pan American Health Organization PAHO, World Health Organization WHO (2019) C_WHO View PDF(8) Download (11) Add to my MEDBOX Given an increase in outbreaks caused by resistant microorganisms associated with medical tourism, the Pan American Health Organization / World Health Organization (PAHO/WHO) encourages Member States to strengthen their capacity to detect and manage infections caused by resistant microorganismsin patients who traveled outside of their country of residence to receive healthcare. Furthermore, PAHO/WHO stresses the importance to implement preventive measures to reduce healthcare-associated infections at all levels of the health system Tags: AMR, Antimicrobial resistance, medical tourism, antibiotics, Source: https://www.paho.org/hq/index.php?option
	Antibacterial agents in preclinical development: an open access database World Health Organization WHO (2019) C_WHO View PDF(17) Download (18) Add to my MEDBOX The pre-clinical pipeline shows more innovation and diversity, with 252 agents being developed to treat WHO priority pathogens. However, these products are in the very early stages of development and still need to be proven effective and safe. The optimistic scenario, the report indicates, is for the first two to five products to become available in about 10 years Tags: Antimicrobial resistance, research, antibacterial, pipeline, pharmaceutical industry, Pharmaceuticals, antibiotics, Source: https://apps.who.int/iris/bitstream/hand
	Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis P. Collignon, J.J.Beggs, T.R. Walsh, et al. (2018) CC Open external link (1067) Add to my MEDBOX The Lancet Planetary Health, Volume 2, ISSUE 9, Pe398-e405, September 01, 2018. Reduction of antibiotic consumption will not be sufficient to control antimicrobial resistance because contagion—the spread of resistant strains and resistance genes—seems to be the dominant contributing factor. Improving sanitation, increasing access to clean water, and ensuring good governance, as well as increasing public health-care expenditure and better regulating the private health sector are all necessary to reduce global antimicrobial resistance Tags: antibiotic resistance, AMR, Anthropology, Socioeconomic context, socioeconomic factors, research, public health, Hygiene, WASH, Sanitation, Source: https://www.thelancet.com/journals/lanpl
	Pathways of antibiotic use in Bangladesh: qualitative protocol for the PAUSE study Rousham E. K., M. Aminul Islam, P. Nahar et al. (2018) C2 Open external link (260) Add to my MEDBOX Global actions to reduce antimicrobial resistance (AMR) include optimising the use of antimicrobial medicines in human and animal health. In countries with weak healthcare regulation, this requires a greater understanding of the drivers of antibiotic use from the perspective of providers and consumers. In Bangladesh, there is limited research on household decision-making and healthcare seeking in relation to antibiotic use and consumption for humans and livestock. Knowledge is similarly lacking on factors influencing the supply and demand for antibiotics among qualified and unqualified healthcare providers. The aim of this study is to conduct integrated research on household decision-making for healthcare and antibiotic use, as well as the awareness, behaviours and priorities of healthcare providers and sellers of antibiotics to translate into policy development and implementatio Tags: AMR, Antimicrobial resistance, Bangladesh, antibiotics, bangladesh, Source: https://www.ncbi.nlm.nih.gov/pmc/article

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