This publication provides an overview of UN Women’s commitments to the humanitarian community guided by the “UN Women strategic plan 2022–2025”. It highlights areas where UN Women has a unique advantage in advancing gender equality and the empowerment of women and girls across the humanitarian–development–peace nexus, and in contributing to the Inter-Agency Standing Committee priorities, including localization and accountability to affected people. The strategy adopts a two-pronged approach: strengthening accountability towards gender commitments in coordination and implementation of UN-led humanitarian and refugee responses, and strengthening comprehensive protection and livelihoods support to crisis-affected women and girls. While taking these approaches, UN Women prioritizes amplifying women’s voices, leadership, and agency as a critical and enabling cross-cutting area.