This toolkit is designed to help you plan and implement a Patient Navigation program with the best chance of reducing health disparities and improving health outcomes for your patients. It contains evidence-based and experience-based examples, case studies, practical tools, and resources to help you: 1. Establish an evidence-based patient navigation program tailored to reduce barriers for your patients 2. Incorporate best practices to enhance current patient navigation programs or services 3. Implement a patient navigation model to address any targeted medical condition where disparities exist 4. Hire, prepare, supervise, support and retain effective Patient Navigators 5. Navigate patients who experience health disparities 6. Evaluate patient navigation programs with the aim of continuous quality improvement