The Lancet October 25, 2022DOI:https://doi.org/10.1016/S0140-6736(22)01540-9 As climate change’s impacts continue to accrue, countries are persistently making wrong choices that are harming human health. A desperate global thirst for fossil fuels is worsening climate change, leading to more extreme weather events that have hit every continent, led to thousands of deaths, and caused $250+ billion in damage in 2021. • People 65+ and children <1 experienced 3.7 billion more heatwave days in 2021 than the annual average from 1986–2005. • Heat-related deaths shot up 68% from 2000–2004 to 2017–2021. • Climate change is abetting infectious disease transmission, warming coastal waters and leading to the spread of Vibrio bacteria like the one that causes cholera, and expanding the reach of the malaria parasite.