Health-care waste management is a critical aspect of health-care systems, crucial for public health and environmental sustainability. This report provides valuable insights into the existing health-care waste management frameworks across 16 countries in the Western Pacific Region. It provides an overview of essential components of the legal framework and best practices, including adoption of environmental friendly technologies in policies and highlights both strengths and areas in need of improvement. The report provides recommendations to enhance the effectiveness and sustainability of future health-care waste management policies in the Region.