Mass population movements have accounted for the emergence of Chagas disease (CD) outside endemic regions, including the European Union/European Economic Area (EU/EEA). The parasite responsible for causing CD, Trypanosoma cruzi (T. cruzi), can be transmitted through substances of human origin (SoHO), such as blood transfusions and organ transplantations [1], posing a risk to the recipients. This, together with congenital transmission, is of increasing concern in non-endemic countries