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n this study, low-dose azithromycin did not meet the prespecified non-inferiority margin compared with standard-dose azithromycin in achieving clinical and serological cure in PCR-confirmed active yaws. Only a single participant (with presumed latent yaws) had definitive serological failure. This wo... more
Fact Sheet, May 2018. Nipah virus (NiV) is a zoonotic virus (it is transmitted from animals to humans) and can also be transmitted through contaminated food or directly between people. In infected people, it causes a range of illnesses from asymptomatic (subclinical) infection to acute respiratory ... more
La fièvre de Lassa est une fièvre hémorragique virale aiguë d'une durée d'une à quatre semaines qui sévit en Afrique occidentale. La fièvre de Lassa, une fièvre hémorragique virale avec des symptômes similaires à ceux de la maladie virale d'Ebola, est endémique dans une grande partie de... more

CDC-DPDx- Leishmaniasis

Division of Parasitic Diseases DPDx Center for Disease Control and Prevention CDC (2017) CC
Leishmaniasis is a vector-borne disease that is transmitted by sandflies and caused by obligate intracellular protozoa of the genus Leishmania. Human infection is caused by about 21 of 30 species that infect mammals. These include the L. donovani complex with 3 species (L. donovani, L. infantum, and... more
The World Health Organization (WHO) endorses the use of population-based prevalence surveys for estimating the prevalence of trachoma. In general, the prevalence of TF in children aged 1–9 years and the prevalence of TT in adults aged ≥ 15 years are measured at the same time in any district bein... more
The World Health Organization (WHO) endorses the use of population-based prevalence surveys for estimating the prevalence of trachoma. In general, the prevalence of TF in children aged 1–9 years and the prevalence of TT in adults aged ≥ 15 years are measured at the same time in any district bein... more
Les présentes lignes directrices ont pour objet de préparer les pays d’endémie à arrêter l’AMM à l’issue du traitement, à passer à la surveillance post-thérapeutique ainsi qu’à confirmer l’interruption de la transmission à l’issue de la phase 2 et à débuter la surveillance p... more
Lymphatic filariasis is a vector-borne neglected tropical disease that causes damage of the lymphatic system and can lead to lymphoedema (elephantiasis) and hydrocele in infected individuals. The global baseline estimate of persons affected by lymphatic filariasis is 25 million men with hydrocele an... more
Recent systematic reviews and meta-analysis of the impact of chemical-based mollusciciding (King et al., 2015, Sokolow et al., 2016) have concluded that regular mollusciciding is likely to contribute significantly towards elimination of schistosomiasis in high-risk areas. The WHO roadmap’s new foc... more
It is Zika virus (ZIKV) that most often causes these neurological effects it appears to be the only arbovirus than can cause congenital malformations such as microcephaly. In any case, more scientific tests are needed to establish the causal relationship between the virus and this malformation (7-10... more
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective pack... more

A guide for surveillance of antimicrobial resistance in leprosy: 2017 update

E. A. Cooreman WHO SEARODepartment of Control of Neglected Tropical Diseases (2017) C_WHO
In case of resistance to rifampicin, fluoroquinolones become the preferred category of second-line drugs. Unfortunately, quinolone-resistant strains of Mycobacterium leprae have also been reported in several countries, probably due to the extensive use of quinolones for treating several types of inf... more
Bula da vacina foi atualizada com nova recomendação para vacina da dengue da Sanofi Aventis para pessoas nunca infectadas pela dengue.
Orientierungshilfe für Ärztinnen und Ärzte
Decision-makers and frontline responders will find a set of resources on plague here. These resources can be used as refreshers for experienced personnel or as an introduction to the topic for everyone else. Most of the materials are available in English and French, and can be downloaded for offline... more
Les décideurs et les intervenants en première ligne trouveront ici les ressources sur la maladie à la peste. Ces ressources peuvent être utilisées en tant que rappels ou compléments de connaissances pour les travailleurs expérimentés ou en tant qu’introduction au sujet pour les autres. La ... more
Contemporary data for causes of vision impairment and blindness form an important basis of recommendations in public health policies. Refreshment of the Global Vision Database with recently published data sources permitted modelling of cause of vision loss data from 1990 to 2015, further disaggregat... more
Brief instructions for the diagnostic of specimens coming from suspected plague cases and exposed contacts, including recommendations for diagnostic confirmation