Toolbox NTDs

Urogenital Schistosomiasis among Schoolchildren and the Associated Risk Factors in Selected Rural Communities of Kwara State, Nigeria

Sundar, S.; Abdulkareem, B.; Habeeb, K. (2018) CC

Urogenital schistosomiasis is a common neglected tropical disease in many rural communities in African countries, with patches of infection in the Eastern Mediterranean Region. Globally, an estimated 239 million people are currently infected, with burden estimated at more than 3.5 million disability ... more

What is Scabies? Fact sheet

Research Institute for Tropical Medicine Department of Health (2018) CC

Scabies is an itchy skin condition caused by a tiny burrowing mite. This eight-legged bug is so small which makes it hard to see on the skin. Approximately 300 million cases of scabies are reported worldwide each year.

Chagas Disease: Provider Fact Sheet

Centers for Disease Control and Prevention (CDC) (2018) C_CDC

Fact Sheet

Treatment of Leprosy

Lockwod DN. The International Textbook of Leprosy (2018) CC

This chapter discusses the antibacterial treatment of leprosy infections. Antibiotic treatment is a key component of leprosy treatment, as it is vital to prevent the progression of the infection. Treatment with rifampin and other antibiotics is highly effective and cures 98% of patients with the ... more

Film - People, Partnerships, and a Pill: 20 Years of ITI

Stanley, R. Productions International Trachoma Initiative; The Taskforce for Global Health (2018) CC

In 2018, we are celebrating 20 years of progress in eliminating trachoma, the world’s leading infectious cause of blindness. Set up in 1998 by Pfizer Inc. and the Edna McConnell Clark Foundation, the International Trachoma Initiative (ITI) supports Ministries of Health in over 30 countries around ... more

Parasitic Diseases Lectures #28: Lymphatic Filariasis

Parasites Without Borders (2018) CC

Dickson and Daniel discuss lymphatic filariasis caused by the helminths Wuchereria bancrofti and Brugia malayai.

Wiping out Trachoma from Nepal – How Nepal eliminated trachoma as a public health problem

World Health Organization World Health Organization WHO (2018) C_WHO

Wiping out Trachoma from Nepal – How Nepal eliminated trachoma as a public health problem WHO - 2018

Official Development Assistance for health in the form of grants by subsectors and programmatic categories

Rüppel J.; Rüppel T. Medmissio Institut (2018) CC

Examples of Donor Profiles

Disability-inclusive social protection research in Vietnam

Banks, Lena M., Walsham, Matthew and others International Centre for Evidence in Disability (2018) C1

A national overview with a case study from Cam Le district
The overall aims of this study are (1) to assess the extent to which social protection systems in Vietnam address the needs of people with disabilities; and (2) to identify and document elements of good practice, as well as challenges, ... more

Laboratory techniques in rabies

Rupprecht, C.; Fooks, A,; Abela-Ridder, B. World Health Organization WHO (2018) C_WHO

Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ... more

Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti ... ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

Enfermedad de Chagas:Hoja informativa para proveedores de atención médica

Centers for Disease Control and Prevention (CDC) (2018) C_CDC

Hoja informativa

Zika, Dengue and Chikungunya Toolkit: Adaptation for Latin America and the Caribbean. School/youth module

International Federation of Red Cross And Red Crescent Societies IFRC (2017) C1

In the battle against diseases like Zika and dengue, knowledge is power. Climate change is shifting the distribution of mosquitoes and to new areas. Empowering communities is essential in reaching and pro- tecting the most vulnerable individuals and households. Vector control programmes, community ... more

Sleeping Sickness - an introduction to African Trypanosomiasis

Let's learn about bugs (2017) C2

Video. Human African Trypanosomiasis, also known as sleeping sickness is a devastating parasitic disease. It is a neglected tropical disease affecting communities in Africa. In this video we take a look at the disease, how it presents and and ways to control it.

Schistosomiasis (Bilharzia)– an overview

Let's Learn About Bugs (2017) CC

Schistosomiasis is a tropical disease caused by a group of parasitic worms. It has an interesting life-cycle involving freshwater snails and can cause short term and long term disease. Schistosomiasis is classified as a neglected tropical disease and affects some of the poorest countries in the worl ... more

CDC-DPDx- Leishmaniasis

Division of Parasitic Diseases DPDx Center for Disease Control and Prevention CDC (2017) CC

Leishmaniasis is a vector-borne disease that is transmitted by sandflies and caused by obligate intracellular protozoa of the genus Leishmania. Human infection is caused by about 21 of 30 species that infect mammals. These include the L. donovani complex with 3 species (L. donovani, L. infantum, and ... more

National Guidelines for TB, DR-TB and Leprosy in Ethiopia
recommended

Federal Ministry of Health, Ethiopia (2017) C1

6th edition

Increasing access to comprehensive care for Chagas disease: development of a patient-centered model in Colombia

Marchiol, A; Forsyth, C.; Bernal, O.; Pan American Health Organization PAHO (2017) C_WHO

Rev. Panam Salud Publica. 2017;41:e153. doi: 10.26633/RPSP.2017.153 Worldwide, over 6 million people are infected with Trypanosoma cruzi, the pathogen that causes Chagas disease (CD). In the Americas, CD creates the greatest burden in disability-adjusted life years of any parasitic infection. In Co ... more

Technical handbook for dengue surveillance, dengue outbreak prediction/detection and outbreak response (“model contingency plan”)

World Health Organization World Health Organization WHO; TDR Program (2017) C_WHO

The aim of this “model contingency plan” is to assist programme managers and planners in devel-oping a national, context-specific, dengue outbreak response plan in order to: (a) detect a dengue outbreak at an early stage through clearly defined and validated alarm signals; (b) precisely define w ... more