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Our awareness necessity of cystic fibrosis (CF) significantly predates our ability to comprehend the molecular factors that underpin its cause and affect prognosis. The dire warning “Woe to that child which when kissed on the forehead tastes salty. He is bewitched and soon must die” has been cir... more

Burden of fungal asthma in Africa: A systematic review and meta-analysis

Kwizera, R.; Musaazi, J.; Meya, D.B.; et al. PLOS ONE, which is part of the Public Library of Science (PLOS) (2019) CC2
Asthma is one of the neglected diseases in Africa with a high prevalence. Allergic fungal diseases have been reported to complicate asthma progression and treatment outcomes. However, data about fungal asthma and its associated complications are limited in Africa. We aimed to estimate the burden of ... more

Asbestos-related diseases in mineworkers: a clinicopathological study

Ndlovu, N.; Rees, D.; Murray, J.; et al. ERJ Open Research, part of the European Respiratory Society (ERS) (2017) CC
This study compared clinical and autopsy findings for three asbestos-related diseases (asbestosis, mesothelioma and lung cancer) in former asbestos mineworkers, and explored factors that influenced agreement between clinical and autopsy findings using data from two compensation systems. In South Afr... more

A 20-year follow-up study on chronic respiratory effects of exposure to cotton dust

Wang, X-R.; Zhang, H-X.; Sun, B-X.; et al. European Respiratory Journal, part of the European Respiratory Society (ERS) (2005) CC2
The article "A 20-year follow-up study on chronic respiratory effects of exposure to cotton dust" evaluates the long-term impact of cotton dust exposure on respiratory health. It followed a cohort of Chinese cotton and silk workers from 1981 to 2001, comparing lung function and symptoms. Results sho... more

Podcast: Chronic Respiratory Disease

Momtazmanesh S., Chiou P. Institute for Health Metrics and Evaluation (IHME) (2023) CC2
The webpage from the Institute for Health Metrics and Evaluation (IHME) features a podcast discussing chronic respiratory diseases and their global impact. It highlights the growing burden of diseases such as chronic obstructive pulmonary disease (COPD) and asthma worldwide. The podcast provides ins... more

Occupational Lung Diseases

John Hopkins Medicine Johns Hopkins Medicine (2024) CC2
The Johns Hopkins Medicine webpage on occupational lung diseases provides an overview of lung conditions caused by exposure to harmful substances in the workplace. It explains various types of occupational lung diseases, including asbestosis, silicosis, coal workers' pneumoconiosis, and hypersensiti... more
This paper summarises the past, present and future of asbestos exposure. The future scenarios as to the mesothelioma incidence in countries, where asbestos has been banned, are discussed.
The "Cystic Fibrosis Fact Sheet" by the National Heart, Lung, and Blood Institute provides an overview of cystic fibrosis (CF), a chronic and often fatal genetic disorder affecting the respiratory and digestive systems. The document outlines the causes, genetic inheritance patterns, and symptoms of ... more

Cystic Fibrosis - Newborn Screening

Pennsylvania Department of Health Pennsylvania Department of Health (2022) CC2
The document "Cystic Fibrosis Key Findings 2023 for Care Providers" by the Pennsylvania Department of Health summarizes recent findings and insights related to cystic fibrosis (CF). It highlights key statistics on the prevalence and outcomes of CF, emphasizes best practices for patient care, and pro... more
The Cedars-Sinai webpage on occupational lung diseases provides an overview of various lung conditions caused by exposure to harmful substances in the workplace. It outlines common types of occupational lung diseases, including asbestosis, silicosis, coal workers’ pneumoconiosis, and chemical-rela... more
The South African Cystic Fibrosis Association (SACFA) is a non-profit organization dedicated to supporting individuals with cystic fibrosis (CF) in South Africa. Their website provides comprehensive information about CF, including its causes, symptoms, and treatment options. CF is described as an in... more

Chronic Respiratory Disease - Asbestosis

Hall A.G. Mediclinic Southern Africa (2008) CC2
The webpage provides detailed information about asbestosis, a lung disease caused by inhaling asbestos fibers. It outlines various asbestos-related diseases, including benign and malignant pleural conditions as well as lung cancer. Asbestosis is described as a diffuse fibrotic disease of lung tissue... more
The Mediclinic Infohub article on silicosis provides an overview of this occupational lung disease caused by inhaling silica dust. It explains that inhaled silica particles lead to lung scarring and nodule formation, progressively impairing breathing. The article outlines symptoms such as shortness ... more

Under- and over-diagnosis of COPD: a global perspective

Ho T., Cusack R.P., Chaudhary N. et al. Breathe, part of the European Respiratory Society (ERS)​ (2019) CC2
The article "Under- and over-diagnosis of COPD: a global perspective" reviews the worldwide variation in the prevalence of chronic obstructive pulmonary disease (COPD) and issues related to its misdiagnosis. It highlights that COPD is under-diagnosed due to factors such as limited access to spiromet... more

The silent epidemic of COPD in Africa

Salvi S. The Lancet Global Health (2015) CC2
The article "The silent epidemic of COPD in Africa" discusses the under-recognized yet significant prevalence of chronic obstructive pulmonary disease (COPD) in Africa. Despite being the third leading cause of death worldwide, COPD remains poorly studied and largely unknown in sub-Saharan Africa. Th... more
The article "The burden of chronic obstructive pulmonary disease and its attributable risk factors in the Middle East and North Africa region, 1990–2019" provides an analysis of the prevalence, mortality, and disability-adjusted life-years (DALYs) due to COPD in the MENA region from 1990 to 2019. ... more
We aimed to estimate the incidence, mortality, disability-adjusted life years (DALYs) for chronic obstructive pulmonary disease (COPD) in 204 countries and territories. We examined the variations in these trends by country, gender, age group, and sociodemographic index (SDI).
There is paucity of data on the burden and specific drivers operative in the pathogenesis of chronic obstructive pulmonary disease (COPD) in the African setting and populations. Lack of awareness and inadequate knowledge on the aetio-pathogenesis of the disease together with inadequate capacity for ... more
The article "Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review" examines the financial impact associated with moderate-to-very severe COPD. The review analyzes studies published between 2006 and 2016 that discuss healthcare resource utilization (HRU), di... more
The article presents findings from the BREATHE study, which assessed the distribution of COPD-related symptoms in the Middle East and North Africa (MENA) region. The study involved a large cross-sectional survey in 11 countries, collecting data on respiratory symptoms, smoking habits, and potential ... more