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Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians
recommended

Médecins Sans Frontières MFS (2023) CC
Cholera is a transmissible diarrhoeal infection caused by Vibrio cholerae. Endemic and/or epidemic in over 40 countries (mainly in Africa and Asia), cholera continues to be a major global public health issue. The World Health Organization (WHO) estimates that the number of cases reported worldwid... more
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Mpox Molecular Diagnostic Tests(RT-PCR)

Africa Center for Disease Control and Prevention (2024) CC
On 13 August 2024, Africa Centres for Disease Control and Prevention (Africa CDC) declared the ongoing Mpox outbreak a Public Health Emergency of Continental Security (PHECS). This was followed the next day by the World Health Organization (WHO), which extended the alert internationally as a public ... more
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SARS-COV-2 Antigen Rapid Diagnostic Test Training
recommended

African Society for Laboratory Medicine ASLM (2021) C1
SARS-COV-2 antigen rapid diagnostic tests are an alternative option for diagnosing active SARS-CoV-2 infection through detection of viral proteins. Rapid antigen tests revolutionize the response to COVID-19 by providing accurate test results in 10 to 20 minutes instead of days, allowing tests to be ... more
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Monitoring and Evaluation of COVID-19 Rapid Antigen Diagnostic Test Rollout in Africa
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1
Limited coverage of laboratory services and long turnaround times from real-time reverse transcription-polymerase chain reaction (rRT-PCR) for the detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been insufficient to meet the demands in many African countries in response... more
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Holistic response strategies for COVID-19

World Health Organization WHO (2020) C_WHO
This document outlines minimum requirements of laboratory testing for COVID-19 and link laboratory testing with surveillance and contact tracing to guide the outbreak response by national health authorities using a reduced number of tests performed. The strategies are organized according to stages o... more
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Report of a WHO–FIND meeting on diagnostics for Buruli ulcer

WHO Tecnical Advisory Group and FIND (2018) CC
The meeting was held from 26 to 27 March 2018 to review and discuss the following topics: Advances and challenges in the use of fTLC, and new approaches to detecting mycolactone using monoclonal antibodies (mAbs). The status of development of rapid diagnostic tests (RDTs) targeting the M... more
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Tropical Medicine Point-of-Care Testing. Update 2022
recommended

Cheesbrough, M. THT Books (2022) C1
To meet the need for laboratory diagnosis to be integrated in community care, the new 2022 Update describes point-of-care tests that can be performed both in district laboratories and peripheral healthcare facilities by non-specialist staff. Also included are recently developed self-tests.
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Drug-resistant tuberculosis: how to interpret rapid molecular test results

World Health Organisation (2020) C_WHO
This training toolkit by the European Laboratory Initiative for TB, HIV and Viral Hepatitis provides a unique combination of practical guidance and expert advice on the interpretation of selected WHO-endorsed tests for drug-resistant tuberculosis (DR-TB).
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Malaria rapid diagnostic test performance. Results of WHO product testing of malaria RDTs round 8 (2016-2018). Summary

World Health Organization WHO; FIND; CDC (2018) C_WHO
This report, published in conjunction with a summary overview of results of rounds 1–8, is the eighth and final report in a series of laboratory-based evaluations of rapid diagnostic tests (RDTs) for malaria. It provides a comparative measure of their performance in a standardized way to distingu... more
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Antigen-detection in the diagnosis of SARS-CoV-2 infection
recommended

World Health Organization WHO (2021) C_WHO
Interim guidance, 6 October 2021 Direct detection of SARS-CoV-2 viral proteins (antigens) in nasal swabs and other respiratory secretions using lateral flow immunoassays (also known as rapid diagnostic tests, RDTs) offers a faster and less expensive method to test for SARS-CoV-2 than the reference ... more
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Learn more about monkeypox as we record first confirmed case in SA

Saphra (2022) CC
South Africa has recorded its first case of monkeypox today, 23 June 2022. The Minister of Health Dr. Joe Phaahla explained that he received a report from the National Health Laboratory Services’ CEO that they have confirmed through laboratory tests the first case of monkeypox in South Africa. ... more
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First meeting of the network on Buruli ulcer PCR laboratories in the WHO African Region Centre Pasteur du Cameroon, Yaoundé, 21–24 October 2019

World Health Organization WHO (2020) CC
Buruli ulcer is caused by infection with Mycobacterium ulcerans. The disease is reported in more than 33 countries worldwide, but only about half of these countries regularly report data to WHO; most cases are reported from subregions of West and Central Africa. The mode of transmission is not known... more
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Use of alternative interferon-gamma release assays for the diagnosis of TB infection: WHO policy statement

World Health Organization WHO (2022) C_WHO
Following review of evidence and advice from the Technical Advisory Group (TAG) on Tuberculosis (TB) Diagnostics and Laboratory Strengthening, the World Health Organization (WHO) announces that current WHO recommendations for the use of interferon-gamma release assays (IGRA) are also valid for Beij... more
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Tool for the diagnosis and care of patients with suspected arboviral diseases

Pan American Health Organization PAHO ; World Health Organization WHO (2017) C_WHO
It is Zika virus (ZIKV) that most often causes these neurological effects it appears to be the only arbovirus than can cause congenital malformations such as microcephaly. In any case, more scientific tests are needed to establish the causal relationship between the virus and this malformation (7-10... more
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Clinical Management of Yellow Fever in the Region of the Americas. Experiences and Recommendations for Health Services

Pan American Health Organisation PAHO (2023) CC
The waves of yellow fever transmission in the Region of the Americas in 2016–2018 involved the largest number of human and epizootic cases to be reported in several decades. Yellow fever is a serious viral hemorrhagic disease that poses a challenge for health professionals. It requires early recog... more
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Communicable Diseases: Part 4 Other Diseases of Public Health Importance and Surveillance.

HEAT, UNICEF, Open University, AMREF Ministry of Health, Federal Democratic Republic of Ethiopia (2015) C1
Blended Learning Modulef or the Health Extension Programme In this study session, you will learn about the general features of faeco-oraldiseases: the main types commonly found in Ethiopia, their general symptomsand signs, how to treat mild cases and when to refer patients with severeconditions for... more
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Symptom-based screening tool for asthma syndrome among young children in Uganda

Nantanda, R.; Siersma, V.; Ndeezi, G. et al. npj Primary Care Respiratory Medicine (2020) CC
Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu... more
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Bénin / Appui à la mise en conformité des procédures d’achat de la CAME

Ministère des Affaires Étrangères, France (2014) C2
La Centrale d’Achats des Médicaments Essentiels et Consommables Médicaux (CAME) du Benin est chargée d’assurer la disponibilité et l’accessibilité des produits de santé dans le secteur publique et privé à but non lucratif. Lors de la mise en oeuvre des subventions du Fonds Mondial, l... more
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Laboratory testing for diphtheria in outbreak settings: Interim guidance, 26 January 2024

World Health Organization WHO (2024) C_WHO
This document provides detailed guidance on laboratory testing for suspected diphtheria cases during significant outbreaks or in low-resource settings. It aims to supplement and build on other existing WHO guidance documents on surveillance standards, diagnostics and research on Corynebacterium by p... more
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Laboratory testing for COVID-19

World Health Organization WHO, Regional Office of Africa (2021) C_WHO