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Holistic response strategies for COVID-19

World Health Organization WHO (2020) C_WHO
This document outlines minimum requirements of laboratory testing for COVID-19 and link laboratory testing with surveillance and contact tracing to guide the outbreak response by national health aut ... more
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Report of a WHO–FIND meeting on diagnostics for Buruli ulcer

World Health Organization World Health Organization WHO Tecnical Advisory Group and FIND (2018) CC
The meeting was held from 26 to 27 March 2018 to review and discuss the following topics: Advances and challenges in the use of fTLC, and new approaches to detecting mycolactone using monoclonal antibodies (mAbs). The status of development of rapid diagnostic ... more
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus ... more
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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus ... more
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Tropical Medicine Point-of-Care Testing. Update 2022
recommended

Cheesbrough, M. THT Books (2022) C1
To meet the need for laboratory diagnosis to be integrated in community care, the new 2022 Update describes point-of-care tests that can be performed both in district laboratories and peripheral hea ... more
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Drug-resistant tuberculosis: how to interpret rapid molecular test results

World Health Organisation (2020) C_WHO
This training toolkit by the European Laboratory Initiative for TB, HIV and Viral Hepatitis provides a unique combination of practical guidance and expert advice on the interpretation of selected WHO-endorsed ... more
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Malaria rapid diagnostic test performance. Results of WHO product testing of malaria RDTs round 8 (2016-2018). Summary

World Health Organization WHO; FIND; CDC (2018) C_WHO
This report, published in conjunction with a summary overview of results of rounds 1–8, is the eighth and final report in a series of laboratory-based evaluations of rapid diagnostic tests (RDTs) ... more
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Antigen-detection in the diagnosis of SARS-CoV-2 infection
recommended

World Health Organization WHO (2021) C_WHO
Interim guidance, 6 October 2021 Direct detection of SARS-CoV-2 viral proteins (antigens) in nasal swabs and other respiratory secretions using lateral flow immunoassays (also known as rapid diagnostic tests, RDTs) offers a faster and less expensiv ... more
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Learn more about monkeypox as we record first confirmed case in SA

Saphra (2022) CC
South Africa has recorded its first case of monkeypox today, 23 June 2022. The Minister of Health Dr. Joe Phaahla explained that he received a report from the National Health Laboratory Services’ CEO that they have confirmed through ... more
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Use of alternative interferon-gamma release assays for the diagnosis of TB infection: WHO policy statement

World Health Organization WHO (2022) C_WHO
Following review of evidence and advice from the Technical Advisory Group (TAG) on Tuberculosis (TB) Diagnostics and Laboratory Strengthening, the World Health Organization (WHO) announces that current WHO recommendations for the use of interferon- ... more
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Tool for the diagnosis and care of patients with suspected arboviral diseases

Pan American Health Organization PAHO ; World Health Organization World Health Organization WHO (2017) C_WHO
It is Zika virus (ZIKV) that most often causes these neurological effects it appears to be the only arbovirus than can cause congenital malformations such as microcephaly. In any case, more scientific tests are needed to establish the causal relatio ... more
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Target Product Profile for a rapid diagnostic test for surveillance of cholera

Global Task Force on Cholera Control (GTFCC) World Health Organisation (WHO) (2024) C_WHO
The WHO Cholera Rapid Diagnostic Test (RDT) Target Product Profile outlines the key requirements for developing improved cholera RDTs. It highlights the need for fast, accurate, and easy-to-use tests for early outbreak detection in resource-limited ... more
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Integrated Managment of Malaria Training

Ministry of Health, Republic of Uganda (2019) CC
This manual is designed to provide comprehensive malaria case management training for health workers at all levels, including clinical, nursing, dispensing, laboratory and records staff. The training covers the use of malaria rapid diagnostic ... more
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Communicable Diseases: Part 4 Other Diseases of Public Health Importance and Surveillance.

HEAT, UNICEF, Open University, AMREF Ministry of Health, Federal Democratic Republic of Ethiopia (2015) C1
Blended Learning Modulef or the Health Extension Programme In this study session, you will learn about the general features of faeco-oraldiseases: the main types commonly found in Ethiopia, their general symptomsand signs, how to treat mild cases and when to refer patients with severeconditions for ... more
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Clinical Management of Yellow Fever in the Region of the Americas. Experiences and Recommendations for Health Services

Pan American Health Organisation PAHO (2023) C_WHO
The waves of yellow fever transmission in the Region of the Americas in 2016–2018 involved the largest number of human and epizootic cases to be reported in several decades. Yellow fever is a serious viral hemorrhagic disease that poses a challenge for health professionals. It requires early recog ... more
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Diagnostic testing for Ebola and Marburg virus diseases: interim guidance, 20 December 2024

World Health Organization WHO (2024) C_WHO
- The goal of diagnostic testing for Ebola and Marburg virus diseases is to identify cases to provide timely and appropriate care and to stop disease transmission. - All individuals meeting the case definition for Ebola or Marburg virus diseases should be tested. - The recommended sample type ... more
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Symptom-based screening tool for asthma syndrome among young children in Uganda

Nantanda, R.; Siersma, V.; Ndeezi, G. et al. npj Primary Care Respiratory Medicine (2020) CC
Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu ... more
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Laboratory testing for diphtheria in outbreak settings: Interim guidance, 26 January 2024

World Health Organization WHO (2024) C_WHO
This document provides detailed guidance on laboratory testing for suspected diphtheria cases during significant outbreaks or in low-resource settings. It aims to supplement and build on other existing WHO guidance documents on surveillance standard ... more
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Laboratory testing for COVID-19

World Health Organization WHO, Regional Office of Africa (2021) C_WHO
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Angezeigte Tests zum neuartigen Coronavirus (SARS-CoV-2) in Deutschland
recommended

Bundesinstitut für Arzneimittel und Medizinprodukte (2020) CC
Tests zur Detektion einer Infektion mit SARS-CoV-2 (neuartiges Coronavirus) sowie zum Nachweis von Antikörpern gehören zu den sog. In-vitro-Diagnostika (IVD). Das erstmalige Inverkehrbringen von In-vitro-Diagnostika auf dem deutschen Markt ist nac ... more