The World Health Organization (WHO) launched the SAFER initiative in 2018 to address the global health and societal challenges posed by alcohol-related harm. The initiative outlines five key strategies aimed at reducing alcohol consumption and its associated consequences. These include strengthening... restrictions on alcohol availability by implementing and enforcing policies to limit its accessibility and advancing drink-driving countermeasures, such as low blood alcohol concentration limits and random breath testing, to reduce alcohol-impaired driving incidents.
Additionally, SAFER emphasizes facilitating access to screening, brief interventions, and treatment for individuals with alcohol use disorders, ensuring that healthcare systems are equipped to provide effective support. Another core strategy is enforcing comprehensive bans or restrictions on alcohol advertising, sponsorship, and promotion to minimize its influence, particularly on vulnerable populations such as youth. Finally, the initiative advocates raising alcohol prices through excise taxes and pricing policies to make it less affordable and thereby reduce consumption.
By implementing these evidence-based, cost-effective measures, the SAFER initiative aims to reduce the global burden of alcohol-related deaths and disabilities, fostering healthier societies worldwide.
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The article investigates the diagnostic capabilities and prevalence of chronic obstructive pulmonary disease (COPD) in primary care settings in northern Brazil. It highlights that COPD is often underdiagnosed and undertreated in resource-limited regions. The study involved 34 general practitioners a...nd used spirometry to evaluate their diagnostic accuracy compared to clinical assessments. Findings revealed significant discrepancies between GP diagnoses and spirometry results, with many false positives and negatives. The study underscores the need for better training and the use of spirometry to improve COPD diagnosis and case-finding in primary care, emphasizing the importance of targeted strategies to enhance healthcare outcomes in developing countries.
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The World Health Organization's fact sheet on noncommunicable diseases (NCDs) highlights that NCDs, such as cardiovascular diseases, cancers, chronic respiratory diseases, and diabetes, are responsible for 74% of all global deaths, totaling 41 million annually. Notably, 86% of premature NCD deaths (...before age 70) occur in low- and middle-income countries. Key risk factors include tobacco use, physical inactivity, harmful alcohol consumption, unhealthy diets, and air pollution. The WHO emphasizes the importance of preventive measures, early detection, and comprehensive healthcare strategies to address the growing NCD burden.
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The Pan American Health Organization (PAHO) provides comprehensive information on noncommunicable diseases (NCDs), including cardiovascular diseases, cancers, diabetes, and chronic respiratory diseases. The website emphasizes that NCDs are the leading cause of death and disability globally, accounti...ng for 71% of all deaths worldwide, with 5.5 million annual deaths in the Americas. It highlights key risk factors such as tobacco use, physical inactivity, harmful alcohol consumption, and unhealthy diets. PAHO advocates for preventive measures, early detection, and integrated healthcare strategies to address the NCD burden in the Americas.
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UNICEF reports that the Democratic Republic of the Congo (DRC) is experiencing its most severe cholera outbreak in six years, with over 31,000 suspected or confirmed cases and 230 deaths in the first seven months of 2023. The North Kivu province is particularly affected, recording more than 21,400 c...ases, including over 8,000 children under five—a sixfold increase compared to all of 2022. The surge is attributed to escalating conflict and displacement in eastern DRC, leading to overcrowded camps with inadequate water and sanitation facilities, creating conditions conducive to cholera transmission. UNICEF emphasizes the urgent need for improved access to clean water, sanitation, and healthcare to prevent further spread of the disease.
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The report provides an epidemiological update on cholera outbreaks in Haiti as of January 17, 2023. Since the first confirmed cases in October 2022, Haiti has reported 24,232 suspected cases, including 1,742 confirmed cases and 483 deaths. The most affected areas are in the Ouest Department, particu...larly Port-au-Prince. Children aged 1 to 4 years are the most affected group. The ongoing humanitarian crisis, security issues, and limited access to healthcare have worsened the outbreak, hindering epidemiological surveillance and case reporting. The PAHO/WHO is working with Haitian authorities to respond to the outbreak and mitigate its spread.
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The GOLD 2023 report provides a comprehensive update on the global strategy for diagnosing, managing, and preventing chronic obstructive pulmonary disease (COPD). It emphasizes that COPD is a leading cause of death worldwide, driven by risk factors such as tobacco smoking, air pollution, and genetic... predispositions. The report outlines key updates, including new diagnostic criteria, the introduction of terms like "Pre-COPD" and "PRISm" for early identification, and expanded sections on comorbidities, pharmacological and non-pharmacological treatments, and rehabilitation. It stresses the importance of personalized treatment plans, early diagnosis, and addressing risk factors to mitigate the disease's impact. The report is aimed at guiding healthcare providers to improve COPD outcomes and adapt treatment approaches based on the latest evidence.
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The Pan American Health Organization (PAHO) provides comprehensive information on noncommunicable diseases (NCDs), including cardiovascular diseases, cancers, diabetes, and chronic respiratory diseases. The website emphasizes that NCDs are the leading cause of death and disability globally, accounti...ng for 71% of all deaths worldwide, with 5.5 million annual deaths in the Americas. It highlights key risk factors such as tobacco use, physical inactivity, harmful alcohol consumption, and unhealthy diets. PAHO advocates for preventive measures, early detection, and integrated healthcare strategies to address the NCD burden in the Americas.
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The article from The Lancet Global Health discusses the "silent epidemic" of chronic obstructive pulmonary disease (COPD) in Africa, emphasizing its status as an under-recognized yet significant health issue. Although COPD is the third leading cause of death globally, it remains largely overlooked i...n African countries. The article highlights studies indicating varying prevalence rates of COPD across sub-Saharan Africa, with major risk factors including tobacco smoking and biomass smoke exposure. The findings suggest that COPD in Africa often affects younger age groups (30–40 years), likely due to early exposure to biomass smoke. The author calls for better education and training for healthcare providers and urges policymakers to address COPD through improved surveillance and effective prevention and treatment strategies.
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The article "The silent epidemic of COPD in Africa" discusses the under-recognized yet significant prevalence of chronic obstructive pulmonary disease (COPD) in Africa. Despite being the third leading cause of death worldwide, COPD remains poorly studied and largely unknown in sub-Saharan Africa. Th...e article highlights risk factors such as tobacco smoking and biomass smoke exposure, which significantly affect both men and women. Biomass smoke, in particular, is linked to COPD in younger individuals and impacts women due to prolonged exposure during cooking. The piece calls for better awareness, training for healthcare providers, and proactive measures to address and manage COPD in the region.
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Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide. There are significant differences in the burden of cardiovascular disease and associated risk factors, across high-income countries and low- and middle-income countries. Cardiac imaging by echocardiography, cardia...c computed tomography, cardiac magnetic resonance imaging, single-photon emission computed tomography, and positron emission tomography myocardial perfusion imaging are well-established non-invasive tests that aid in the diagnosis, risk stratification, and management of various cardiac diseases. However, there are significant inequalities in availability and access to imaging modalities in low- and middle-income countries attributed to financial constraints, disparities in healthcare and technical infrastructure. In the post-COVID-19 pandemic era, these disparities are exaggerated by the continued technological advancements driving innovations in the field of cardiovascular (CV) imaging in high-income countries, while there is an urgent need to provide sustainable access to diagnostic imaging for patients in economically strained healthcare systems in regions like Africa. This review aims to highlight the inequalities in the burden of cardiac disease, associated risk factors, and access to diagnostic CV imaging tests, while also exploring the need for sustainable solutions to implementing CV imaging all over the world.
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Wits Reproductive Health and HIV Institute (Wits RHI) is involved in an effort to curb the COVID-19 pandemic that is facing South Africa and the world at large. Prof. Helen Rees is a member of the team advising the Health Minister on COVID-19 (MAC). She is part of the Clinicians Group, the Research ...group and the Incident Management Team (IMT). Prof. Rees is Co-Chair of the South African arm of the Solidarity study
This is a World Health Organisation (WHO) coordinated trial that will generate high quality evidence on COVID-19 treatment options. Prof Helen is also the International Coordinator for the global Crown Coronation study. This study is aimed at looking at strategies to protect healthcare workers.
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The pharmacological treatment of heart failure has evolved over the last three decades since the demonstration of the effect of angiotensinconverting enzyme inhibitors on major cardiovascular events in patients with heart failure with reduced ejection fraction. Composite analysis of heart failure wi...th reduced ejection fraction trials and the recent identification of newer drug treatments show early benefits on the major cardiovascular outcomes, ushering in a change of the treatment strategy; from a ‘sequential’ initiation of the treatments to a ‘simultaneous’ initiation to harness the early benefits. The adoption and implementation of these changes at the bedside have been dismal in many healthcare settings. Papua New Guinea, like many other lower-to-middle-income countries, is facing many barriers that impact on the care of heart failure patients. It needs to adopt and implement these changes to provide evidence-based treatment for its people with heart failure with reduced ejection fraction.
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Noncommunicable diseases (NCDs) are chronic medical conditions that are not spread from person to person. Unlike infectious diseases, which are caused by bacteria, viruses, or other pathogens, NCDs are typically long-lasting and result from a combination of genetic, physiological, environmental, and... behavioral factors. NCDs are the leading cause of death worldwide and responsible for over 70% of global deaths each year. Over 80% of these deaths occur in low- and middle-income countries (WHO). Noncommunicable diseases pose a serious threat to global health because they are widespread, costly, largely preventable, and responsible for the majority of deaths worldwide. Reducing their impact requires coordinated efforts in prevention, early detection, and healthcare system strengthening, particularly in lower-income countries. The Toolbox on Noncommunicable Diseases (NCDs) can play a vital role in strengthening Global Healthcare systems by providing centralized, reliable, and up-to-date health information and resources like clinical guidlelines, education material as well as tools for prevention and health promotion.
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Malaria is an infection caused by Plasmodium species endemic to most parts of Africa, South America, East Asia, and parts of Europe and the Middle East. At least 10 to 30 thousand of the 125 million travelers to these areas are infected each year. All visitors to endemic areas should receive counsel...ing on malaria risk, mosquito bite avoidance, and tailored chemoprophylaxis based on their medical histories and travel plans. This activity reviews the evaluation and management of chemoprophylaxis of malaria and highlights the role of the healthcare team in improving care for patients with potential exposure to this condition.
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This table summarises the drugs used for malaria prevention, including adult and paediatric dosages, timing and special considerations. The medications listed are atovaquone/proguanil, chloroquine, doxycycline, hydroxychloroquine, mefloquine, primaquine and tafenoquine. The guidance covers the use o...f these drugs for primary and terminal prophylaxis, as well as contraindications (e.g. G6PD deficiency, pregnancy, and psychiatric or cardiac conditions) and safety precautions for children and special populations. The aim is to help travellers and healthcare providers reduce the risk of malaria during travel.
Accessed on 27/08/2025.
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Antimicrobial resistance (AMR) and malaria remain significant public health challenges in the WHO Eastern Mediterranean Region (EMR). In 2021, the region reported 1.7 million sepsis-related deaths, with 373,000 associated with bacterial AMR. High antibiotic consumption, particularly in high-income c...ountries, combined with rising usage in middle-income countries, has accelerated the emergence of drug-resistant infections. Malaria management is further complicated by biological threats, including vector insecticide resistance, PFHRP2/3 gene deletions, and antimalarial drug resistance, alongside insufficient trained personnel and limited molecular surveillance capacity. Effective strategies to address these challenges include strengthening regional and cross-border surveillance networks, designating WHO collaborating centers for molecular monitoring, enforcing national treatment policies, and raising public and healthcare provider awareness about rational antimalarial and antibiotic use. These measures, coupled with sustainable funding and enhanced therapeutic efficacy studies, are essential to reduce the development and spread of drug-resistant malaria and improve overall health outcomes in the EMR.
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This case study examines the humanitarian response to the conflict-related crisis in the North-East of Nigeria, focusing primarily on the period from 2015 to the end of 2016. The aim is test the central hypotheses of the Emergency Gap project: that the current structure, conceptual underpinning and... prevalent mindset of the international humanitarian system limits its capacity to be effective in response to conflict-related emergencies.
As with many conflict-related crises, the emergency in north-east Nigeria has deep and complex roots in the history of the region. The conflict began in 2009 and quickly developed beyond the control of the authorities. It unfolded in the midst of pre-existing political, social and economic tensions, making an effective humanitarian response exceedingly difficult. Despite this complexity, what is clear is that the crisis has resulted in a sprawling humanitarian disaster that has killed over 25,000 people as a direct result of the violence, and continues to devastate many more lives through hunger, psychological trauma and lack of access to healthcare.
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Diabetes is one of the leading causes of death globally. India is home to the second-largest population suffering from diabetes. This underscores the need to build capacity of primary care physicians (PCPs) for better disease management. This narrative review article aims to describe the emergence o...f diabetes education and capacity-building programs for PCPs and its current situation in India. The review highlighted that major emphasis on diabetes was given only when the WHO estimated that morbidity and mortality due to diabetes would increase to 35% in India. As a result, National Diabetes Control Program was launched in 1987. Yet, very little attention was paid to diabetology in under-graduation. In the last decade, few public and private institutions have developed diabetes related capacity-building programs for PCPs independently or in collaborations. These programs include 16 fellowships, 4 diplomas, 12 certificate programs, and 6 other diabetes training programs, which have their own pros and cons. As medical science is changing rapidly, PCPs need to upgrade their skills and knowledge regularly to manage NCDs such as diabetes more effectively and efficiently. This can be possible only if scientific, evidence-based, and quality-oriented capacity-building programs are provided to the healthcare workforce.
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We reviewed the evidence on community-based interventions for the prevention and control of cutaneous leishmaniasis (CL). Community initiatives tailored towards awareness and mobilisation are regarded as a priority area in the Neglected Tropical Disease Roadmap 2021–2030 by the World Health Organi...zation. We searched nine electronic databases for intervention-based
studies. Two independent reviewers screened and assessed the articles for methodological quality using predefined criteria. We conducted a meta-analysis using a random effects model, along with narrative synthesis. Thirteen articles were eligible for inclusion, of which 12 were quantitative studies (quasi-experimental with control group and pre-post interventions) and one qualitative
study. All articles reported on health education interventions aimed at changing people’s knowledge, attitudes, and practices (KAP) in relation to CL. Participant groups included students, mothers, housewives, volunteer health workers, and residents in general. An increased score was recorded for all outcomes across all interventions: knowledge (SMD: 1.85, 95% CI: 1.23, 2.47), attitudes (SMD:
1.36, 95% CI: 0.56, 2.15), and practices (SMD: 1.73, 95% CI: 0.99, 2.47). Whilst our findings show that educational interventions improved people’s knowledge, attitudes, and practices about CL, we argue that this approach is not sufficient for the prevention and control of this disease. Knowledge does not always translate into action, particularly where other structural barriers exist. Therefore,
we recommend the design of more innovative community-based interventions with a broader focus (e.g., stigma, financial barriers, and healthcare access).
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