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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2... more

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Journey of ART Programme in India. Story of a decade

National AIDSControl (NACO), Government of India; Ministry of Health and Family Welfare, et al. (2015) C1

Celebrating ten years of success 2004-2014

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ASEAN Disaster Management Reference Handbooks

Center for Excellence in Disaster Management and Humanitarian Assistance (2022) C1

Disaster Management Reference Handbook Series Overview. Floods, storms, and wind account for large proportions of displacement compared to other disasters. Floods are the most frequent type of disaster whereas wind-related disasters constitute the biggest losses in terms of economic damage, displac... more

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Handbook for Emergencies

UNHCR (2007) C2

Section One summarizes UNHCR’s mandate of international protecdtion and the aim and principles of emergency response; Section Two deals with emergency management; Section Three covers the vital sectors and problem areas in refugee emergencies, including health, food, sanitation and water, a... more

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Migration flows in Latin America and the Caribbean - Situation Report 5

UNICEF UNICEF (2019)

As of June 2019, the number of Venezuelans leaving their country reached 4 million, with Colombia, Peru, Chile, Ecuador and Brazil hosting the vast majority of Venezuelans in Latin America. The end of the first half of the year was marked by the announcement of tighter immigration measures in Peru ... more

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India: health system review

Srivastava, Swati, Karan, Anup K., Bhan, Nandita, Mukhopadhya, Indranil. et al. .World Health Organization (WHO), Regional Office for South-East Asia (2022) C_WHO

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Putting HIV and HCV to the test - A product guide for point-of-care CD4 tests and laboratory-based and point-of-care HIV and HCV viral load tests

Medecins Sans Frontieres (Access Campaign) (2017) C2

3rd Edition – July 2017 www.msfaccess.org

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Interim Guidance on Public Health and Social Measures for COVID-19 Preparedness and Response Operations in Low Capacity and Humanitarian Settings

Inter-Agency Standing Committee IASC (2020) C1

This Interim Guidance outlines how key public health and social measures needed to reduce the risk of COVID-19 spread and the impact of the disease can be adapted for use in low capacity and humanitarian settings. The recommendations outlined here need to be adjusted to the scale of transmission, co... more

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Diagnostic testing for SARS-CoV-2: interim guidance, 11 September 2020

World Health Organization WHO (2020) C_WHO

Available in Arabic, Chinese, English, French, Portuguese and Spanish https://apps.who.int/iris/handle/10665/334254

External Link

Health workforce policy and management in the context of the COVID-19 pandemic response

World Health Organization WHO (2021) C_WHO

This guide is available in English, French, Spanish, Russian, Arabic and Chinese This guide consolidates COVID-19 guidance for human resources for health managers and policy-makers at national, subnational and facility levels to design, manage and preserve the workforce necessary to manage the COVI... more

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Infection prevention and control in the context of coronavirus disease (‎COVID-19)‎: a living guideline, 9 October 2023

World Health Organization WHO (2023) CC

The Infection prevention and control in the context of coronavirus disease 2019 (COVID-19): a living guideline consolidates technical guidance developed and published during the COVID-19 pandemic into evidence-informed recommendations for infection prevention and control (IPC). This living guideline... more

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The Health Literacy Toolkit For Low- and Middle-Income Countries

Sarity Dodson, Suvajee Good and Richard Osborne World Health Organization - Regional Office South-East Asia (2015)

A series of information sheets to help empower communities and strengthen health systems This series of information sheets introduces health literacy, its relevance to public policy, and the ways it can be used to inform the promotion of good health, the prevention and management of communicab... more

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Annual Report NACO 2013 - 14

NACO, Department of AIDS Control (2013)

Department of AIDS Control Ministry of Health & Family Welfare

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Strategic plan for the prevention and control of multidrug-resistant and extensively drug-resistant tuberculosis in the Eastern Mediterranean Region (2010–2015)

World Health Organization Eastern Mediterranean (2010) C_WHO

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Zambia Steps for Non Communicable Risk Factors

Ministry of Health, Zambia Bloomberg Philanthropic; WHO, Path, et al. (2017) CC

Zambia Report for 2017

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Introduction to Low Cost Sanitation
recommended

Centre for Affordable Water and Sanitation Technology CAWST (2011) CC

Planning, Promotion, Contruction & Design. Manual

External Link

Guidance on operational microplanning for COVID-19 vaccination

World Health Organization WHO (2021) C_WHO

This publication is a companion document to the NDVP National Deployment and Vaccination Plans guidance, which provides a framework for countries to develop their national strategies. As countries face challenges with erratic vaccine supplies, use of multiple vaccine products with different charact... more

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Guidelines for the Management of Drug Resistant Tuberculosis in Kenya

Ministry of Public Health and Sanitation, Kenya (2010) CC

Introduction to Low Cost Sanitation recommended

Introduction to Low Cost Sanitation
recommended