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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc ... e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

Social science and behavioural data compilation, DRC Ebola outbreak, June - August 2019

Bardosh, K.; T. Jones and J. Bedford Social Science in Humanitarian Action: A Communication for Development Platform (2019) C1

This rapid compilation of data analyses provides a ‘stock-take’ of social science and behavioural data related to the on-going outbreak of Ebola in North Kivu, South Kivu and Ituri provinces. Based on data gathered and analysed by organisations working in the Ebola response and in the region mor ... more

Integrating severe acute malnutrition into the management of childhood diseases at community level in South Sudan

Emily Keane, Andrea King, Anthony Awira et al. Malaria Consortium South Sudan (2013) C1

Since December 2010, Malaria Consortium has been implementing an innovative approach to community management of severe acute malnutrition, together with an existing integrated community case management (ICCM) programme in South Sudan. This learning paper considers Malaria Consortiums experience of t ... more

Malawi National Guidelines for Kangaroo Mother Care

Ministry of Health, Malawi (2009) C1

Guidelines

Way forward to archieving sustainable AIDS results

UNAIDS UNAIDS (2018) C2

Agenda item 􏰀5, UNAIDS/PCB (43)/18.􏰁􏰀 11-13 December 2018 | Geneva, Switzerland UNAIDS Programme Coordinating Board Issue date: 23 November 2018

Implementation manual to support the prevention of surgical site infections at the facility level: turning recommendations into practice
recommended

World Health Organization WHO (2020) C_WHO

TACKLING ANTIMICROBIAL RESISTANCE (AMR) TOGETHER Working Paper 5.0: Enhancing the focus on gender and equity

World Health Organization WHO (2018) C_WHO

This document aims to assist countries to take the first step towards better considering gender and equity issues in their efforts to tackle antimicrobial resistance (AMR), to inform the implementation of strategies in national action plans and contribute to improved reach and effectiveness of AMR e ... more

Accelerating anaemia reduction: a comprehensive framework for action

World Health Organisation (WHO) (2023) C_WHO

This document is an output of a WHO cross-programme initiative aiming to improve the prevention, diagnosis and management of anaemia and thereby accelerate reduction in its prevalence. It comes at an important time, midway through the era of the Sustainable Development Goals, when progress in reduci ... more

HIV and TB Intervention in Prisons & other closed Settings

Ministry of Health & Family Welfare, India; NACO; et al. (2018) C1

Operational Guideline

WHO guideline: the use of safety-engineered syringes for intramuscular, intradermal and subcutaneous injections in health care settings

World Health Organization WHO (2016) C_WHO

Injection practices worldwide and especially in low- and middle-income countries (LMICs) include multiple, avoidable unsafe practices that ultimately lead to the large-scale transmission of bloodborne viruses among patients, health care providers and the community at large.

Child and adolescent health in humanitarian settings: operational guide: a holistic approach for programme managers

World Health Organization WHO; Eastern Mediterranean Region (2022) C_WHO

Rohingya Refugee Response Gender Analysis: Recognizing and responding to gender inequalities

Toma, Iulia; Chowdhury, Mita; Laiju, Mushfika; Gora, Nina; Padamada, Nicola Oxfam, Action Against Hunger, Save the Children (2018) C1

This gender analysis was conducted to understand the different risks and vulnerabilities but also opportunities and skills for Rohingya and host community women, men, boys and girls. Data collection was conducted over three weeks from 8 April to 29 April 2018. The work aimed to identify the differen ... more

Coverage at a crossroads: New directions for vitamin A supplementation programmes

United Nations Children’s Fund (UNICEF) (2018)

In where under-five mortality is high and vitamin A deficiency is a public health problem, two high-dose supplements of vitamin A per year, spaced four to six months apart, can strengthen children’s immune systems and improve their chances of survival.
During much of early childhood – from ... more

Executive Summary - Chapter 6 Prevention

T. Stockwell ATLAS on substance use (2010)— Resources for the prevention and treatment of substance use disorder; WHO (2019) C_WHO

ATLAS on substance use (2010)— Resources for the prevention and treatment of substance use disorder Accessed: 14.03.2019

Global Technical Strategy for Malaria 2016–2030, 2021 Update

Pedro Alonso, Kevin Baird, David Brandling-Bennett et al. World Health Organization (WHO) (2022) C_WHO

This updated version, endorsed by the World Health Assembly in May 2021 through resolution WHA74.9, reflects lessons learned in the global malaria response over the last 5 years. While the milestones and targets remain the same, the approaches to tackling the disease, in some areas, have evolved to ... more

Issue Brief NTDs Part 3 : Schistosomiasis
recommended

Mauder S. The MEDBOX Team (2025) CC

In this subsequent part of the issue brief on the NTD Toolbox you will learn about general strategies, roadmaps, key treatment guidelines, reports, and training material on Schistosomiasis

HIV/AIDS + Work - A handbook on HIV/AIDS for labour and factory inspector

nternational Labour Organization International Labour Organization (2005) C2

This handbook aims to help labour inspectors deal with the issue of HIV/AIDS. It establishes the links between the key principles and core responsibilities of labour inspectorates and the management of HIV/ AIDS at the workplace. It includes training activities and practical tools to help inspecto ... more

Educação e HIV Evolução e perspectivas

Ma. B. Alves de Souza; P. Ozório; et al. Edições UNESCO (Organização das Nações Unidas para a Educação, a Ciência e a Cultura) (2016) C2

Educação em movimento

Serving the needs of Key Populations: Case examples of innovation and good practice in HIV Prevention, Diagnosis, Treatment and Care

A. Armstrong; C. Irvine; C. Figueroa; A. Verster; R. Baggaley et al. World Health Organization (2017) C_WHO

Key Populations