This document provides an overview of malaria rapid diagnostic tests (RDTs) for Principal Recipients (PRs) of Global Fund grants, indicating their eligibility for procurement under the Global Fund's Quality Assurance Policy. The included products have been assessed and approved by the WHO Prequalifi...cation of Diagnostics Programme (WHO PQ), the relevant regulatory authorities of the GHTF founding members or the Global Fund Expert Review Panel for Diagnostics (ERPD). Updates are made based on new evidence and regulatory assessments.
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Antimalarial chemotherapy is crucial for reducing morbidity, mortality, and drug resistance, and is the cornerstone of malaria control. Existing antimalarial drugs act at different stages of the parasite’s life cycle. These drugs range from classic agents such as chloroquine and quinine to newer a...rtemisinin derivatives. They include tissue schizonticides, blood schizonticides, gametocytocides, and sporontocides. Artemisinin and its derivatives are the most effective and fastest-acting treatment against drug-resistant Plasmodium falciparum, achieving rapid parasite clearance and reducing transmission potential. Other key drugs include mefloquine, halofantrine, proguanil, sulfadoxine–pyrimethamine, atovaquone–proguanil, tetracyclines, clindamycin and azithromycin. Each of these drugs has a specific mechanism of action, pharmacokinetics, efficacy, safety profile and contraindications. Rational drug combinations and adherence to national treatment guidelines are essential for managing resistance, ensuring safety in vulnerable populations such as children and pregnant women, and optimising therapeutic outcomes in cases of both uncomplicated and severe malaria.
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Every two minutes, a child under the age of 5 dies from malaria. Under-five children accounted for 67 per cent of all malaria deaths worldwide in 2018. Most of them occurred in sub-Saharan Africa where an estimated 24 million children were infected with its deadliest form. In addition to being the t...hird-deadliest infectious disease for children, malaria infection and the costs of treatment traps families in a cycle of illness, suffering and poverty.This year’s World Malaria Day is marred by the emergence of the COVID-19 outbreak, which further threatens people’s lives and well-being. Public health officials are taking precautionary and often aggressive measures to limit transmission of this virus, including reductions in social movement, physical distancing, hand-washing and recommending the use of personal protection equipment in high-risk settings. However, while focusing on combating this disease, the world cannot afford to ignore other diseases, such as malaria.
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To guide the provision of quality palliative care services across the African region, the African Palliative Care Association (APCA) has developed a framework of core palliative care competencies that can be used by service providers, educators and other stakeholders to guide programmes development.
The guide helps patients to understand their rights in relation to the care received and provides insights into the common legal and
human rights issues they may encounter, and encourages them to share these with the health care provider for support. This booklet covers key issues that you mig...ht need to understand about ethical care, human rights and legal aspects. It aims to help people with serious illness as they face these issues, and give them guidance on how they can find solutions.
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The African Palliative Care Association is pleased to publish the first edition of Palliative Care Standards for Africa. The development of these standards was achieved through wide consultation with service beneficiaries and providers, and they have been developed to suit different levels of ... service delivery, from primary to tertiary. These standards are underpinned by the World Health Organization’s definition of palliative care, and recognise that scaling up palliative care requires a public health approach with four pillars: policy, education, drug availability and implementation. In addition, the increasing need to establish specific indicators of quality and effectiveness for palliative care has been a big driving force behind these comprehensive standards. It is APCA’s wish that they will provide a framework for the development of evaluation
and performance indicators that can facilitate programme improvement and development. The standards are designed to allow the development or improvement of palliative care across the different services levels, within the organisational capacity of various service providers. They describe a relationship between primary, intermediary and tertiary level service providers, with expectations for all providers articulated through detailed criteria for each standard. It is therefore expected that these standards will influence the planning and delivery of palliative care services at all levels of health care service delivery.
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Palliative care is an approach that improves the quality of life of patients (adults and children) and their families who are facing problems associated with life-threatening illness. It prevents and relieves suffering through the early identification, correct assessment and treatment of pain and ot...her problems, whether physical, psychosocial or spiritual.
Addressing suffering involves taking care of issues beyond physical symptoms. Palliative care uses a team approach to support patients and their caregivers. This includes addressing practical needs and providing bereavement counselling. It offers a support system to help patients live as actively as possible until death.
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Internal displacements due to conflict and disasters are a major driver of global human mobility. While the total numbers of internal displacements by cause and geographical location are increasingly well tracked, a significant gap remains in the availability of disaggregated data on key variables ... such as age, sex, education, livelihood – for the populations impacted by these events. Data from localised case studies can provide this granularity; however, they are difficult to generalise to other contexts. This lack of disaggregated profiles complicates the work of decision makers tasked with allocating resources efficiently to address the diverse
vulnerabilities and needs of impacted communities
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Internal displacements due to conflict and disasters are a major driver of global human mobility. While the total numbers of internal displacements by cause and geographical location are increasingly well tracked, a significant gap remains in the availability of disaggregated data on key variables ... such as age, sex, education, livelihood – for the populations impacted by these events. Data from localised case studies can provide this granularity; however, they are difficult to generalise to other contexts. This lack of disaggregated profiles complicates the work of decision makers tasked with allocating resources efficiently to address the diverse
vulnerabilities and needs of impacted communities
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In conclusion, the current evidence does not support the use of mpox antigen RDTs in the field. More data are expected from independent evaluations conducted by Africa CDC, FIND or other organizations
WHO, as the coordinating authority on international health, supports countries in protecting public health through evidence-based policies and actions. Considering the significant health burden and the multiple potential benefits of interventions, the WHO Air Quality, Energy and Health Unit aims to ...support countries by providing evidence, building institutional capacity and leveraging the “health argument” to convene sectors to tackle air pollution and accelerate energy access.
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Promoting and protecting the mental health and psychosocial wellbeing of children, adolescents, and their caregivers remains undamental to achieving the Sustainable Development Goals (SDGs), with a direct contribution to SDG 3 (Good Health and Well- eing). In 2024, UNICEF accelerated the scale-up o...f integrated, multisectoral MHPSS programming. These efforts contributed to the strengthening of national and subnational child and adolescent mental health systems by supporting programming across the continuum of care, investing in workforce development, advancing data systems and evidence generation, and promoting institutional leadership and coordination mechanisms. UNICEF’s growing reach, particularly through health, education, and child protection systems, reflects a strategic commitment to embedding MHPSS in sustainable development frameworks and in responses that bridge humanitarian action and development programming.
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The future is inherently uncertain, and while we hope to avoid another pandemic, hope alone is not a strategy. To ensure we are better prepared, it is important to proactively explore plausible futures through structured foresight exercises.
The ADPC Digital Library is a comprehensive hub for all the resources, publications, and knowledge products developed by ADPC. It provides easy access to a wide range of materials, including research reports, policy briefs, training manuals, case studies, and technical guidelines on disaster risk re...duction, climate resilience, and emergency preparednes
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A Joint External Evaluation (JEE) is an essential component of the International Health Regulations (IHR) Monitoring and Evaluation Framework (IHR MEF). The process involves a self-assessment by the country, followed by an evaluation conducted by an independent JEE team using a standardized tool. Th...is tool assesses 19 technical areas across four domains: prevention, detection, response, and other hazards and points of entry.
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This is an online orientation to strengthen the competencies of health sector actors working in emergencies to establish, support and scale up Mental Health and Psychosocial Support (MHPSS) in countries. The focus of this channel is on how to apply existing practical, evidence-based, scalable tools ...and practice-led approaches for successful implementation of projects to strengthen MHPSS in emergencies operations, protection from mental health and psychosocial consequences of crises and towards the realization of universal mental health coverage.
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Parliaments and parliamentarians play a unique and powerful role in achieving health security preparedness through their various responsibilities: law-making, oversight, budgetary allocation, and citizen representation. High-level reviews of the response to the COVID-19 pandemic emphasized the impor...tance of state capacity, social trust, and leadership when it comes to health emergency preparedness. Parliaments and parliamentarians are extremely well positioned to support, build, and strengthen these three aspects.
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There is widespread recognition of the growing threat of infectious disease epidemics and pandemics spreading across countries or continents—especially following the recent Ebola and COVID-19 pandemics. Vulnerable groups (including children, older adults, ethnic minorities and other at-risk group...s) have disproportionately borne the brunt of significant health, social, and economic effects of these epidemics and pandemics, with varying degrees of support received depending on the context. While many argue that communities should or need to play a critical role in supporting and leading preparedness and response efforts, work still needs to be done to engage them effectively. In many instances, modes of engagement with communities—especially by state authorities–have come too late, often as an afterthought are not adequately thought through and have undermined public trust in and support for, disease prevention and control measures
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With an estimated population of about 5 million and an annual growth rate of 8 per cent, Dar es Salaam, Tanzania, is Africa’s fastest growing city.1 Over 70 per cent of the people live in informal, unplanned settlements with inadequate infrastructure. In addition, heavy rainfalls twice a year ...result in signifi cant fl ood risks. The objectives in Dar es Salaam were to 1) obtain high quality and up to date exposure maps of aff ected communities and as a stretch goal 2) to create a hydrological model using elevation data. Both of these would form important elements to managing fl ood risks but neither had been previously available due to a lack of high quality digital imagery
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The purpose of this manual is to provide guidance on how to implement Pan American Health Organization (PAHO) recommendations for malaria elimination at the local level. It is a streamlined, more operational version of the Manual for Stratifying Malaria Risk and Elimination of Foci, aimed primarily ...at operational teams working in the field. The content has been prioritized and the steps of the process organized to facilitate greater understanding by local teams. Adjustments have also been made to underscore its versatility for all malaria transmission scenarios in the Region of the Americas.
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