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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Kenya National Cancer Treatment Protocols

Ministry of Health, Kenya Ministry of health (2019) C1

The key areas covered are diagnosis, imaging, pathology, surgery, rehabilitation, palliative care and survivorship. It emphasizes a multi-disciplinary team approach which is paramount for quality cancer care. The specific cancers covered are breast, central nervous system, gastroint... more

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When the Drugs Don’t Work – Antibiotic Resistance as a Global Development Problem

The Dag Hammarskjöld Foundation and ReAct (2019) C2

This paper focuses on the Sustainable Development Goals related to poverty, economic growth, inequality, health, food production and the environment. It presents concrete examples of the underlying and complex aspects of antibiotic resistance and its impacts across different Sustainable Development ... more

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Healthy environments for healthier populations: why do they matter and what can we do?

World Health Organisation WHO (2019) C_WHO

Known avoidable environmental risks to health cause at least 12.6 million deaths every year, and account for about one quarter of the global burden of disease (2016 data) (1). Air pollution alone causes about 7 million deaths a year, placing it among the top global risks to health (2). Global envir... more

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Overlapping Vulerabilities - The impacts of climate change on humanitarian needs

Norwegian Red Cross (2019) C1

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World Alzheimer Report 2019

Prince, M., and J. Jackson Alzheimer's Disease International (2019) C2

Some of the key findings of the report include: Almost 80% of the general public are concerned about developing dementia at some point and 1 in 4 people think that there is nothing we can do to prevent dementia 35% of carers across the world said that they have hidden the diagnosis of de... more

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Herramienta de la OMS para la implementación de la profilaxis previa a la exposición al VIH - Módulo 4

Organización Mundial de la Salud (Américas); Organización Panamericana de la Salud Organización Mundial de la Salud (Américas); Organización Panamericana de la Salud (2019) C_WHO

Módulo 4 Líderes Julio del 2017 Módulo 4: Líderes. Este módulo tiene por objeto informar y actualizar a los líderes y a los encargados de tomar decisiones sobre la PrEP. Proporciona información sobre los beneficios y las limitaciones de la PrEP para que puedan considerar cómo pueden a... more

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Safe listening. Devices and Systems

World Health Organization WHO (2019) C_WHO

A WHO-ITU Standard. Nearly 50% of people aged 12-35 years – or 1.1 billion young people – are at risk of hearing loss due to prolonged and excessive exposure to loud sounds, including music they listen to through personal audio devices. Ahead of World Hearing Day (3 March), the World Health Org... more

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Marketing of breast-milk substitutes: national implmentation of the international code

World Health Organization WHO (2019) C_WHO

Status Report 2018

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Towards transformative integration of the HIV and AIDS response into universal health coverage: Building on the strengths and successes of the HIV and AIDS response

G. Ooms; K. Kruja; M. Hart; D. Ruiz Aidsfonds; PITCH (Partnership to Inspire, Transform and Connect the HIV response) (2019) C2

Experiences from Indonesia, Kenya, Uganda and Ukraine

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Monitoring food and beverage marketing to children via television in the Kyrgyz Republic

World Health OrganizationEurope (2019) C_WHO

This report summarizes the results of a 2018 survey of food and beverage marketing to children via television in the Kyrgyz Republic. It explores the extent and nature of children’s exposure to marketing for food high in saturated fat, free sugars and/or salt via television in the country. The stu... more

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Guidelines for long-lasting insecticidal nets care, repurposing and disposal

Ministry of Health Uganda, WHO Uganda WHO Regional Office for Africa (2019) C_WHO

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Human Devastation Syndrome: The Impact of Conflict on Mental Health

Syrian American Medical Society (SAMS) (2018) C1

The magnitude and complexity of these mental health conditions caused by prolonged and extensive trauma requires a diagnosis fitting the unique context of the Syrian conflict. Over half a million people have been killed since the beginning of the conflict in 2011, and more than 6.4 million are inter... more

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Guidelines on sanitation and health
recommended

World Health Organization WHO (2018) C_WHO

The new WHO Guidelines on Sanitation and Health summarize the evidence on the effectiveness of a range of sanitation interventions and provide a comprehensive framework for health-protecting sanitation, covering policy and governance measures, implementation of sanitation technologies, systems and b... more

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Pretreatment drug resistance and new treatment paradigms in firstline ART

Moorhouse, M. Southern African HIV Cinicans Society (2018) C2

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WHO Report on Surveillance of Antibiotic Consumption

World Health Organization WHO (2018) C_WHO

2016-2018 Early implementation, This report presents 2015 data on the consumption of systemic antibiotics from 65 countries and areas, contributing to our understanding of how antibiotics are used in these countries. In addition, the report documents early efforts of the World Health Organization (... more