This publication seeks to describe the best treatments and practices based on the scientific evidence available at the time of writing as evaluated by the authors and may change as a result of new research. Readers need to apply this knowledge to patients in accordance with the guidelines and laws o...f their country of practice. Some medications may not be available in some countries and readers should consult the specific drug information since not all the unwanted effects of medications are mentioned.
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Nature | Vol 600 | 2 December 2021 |
Geflüchtete Menschen sind vielfältigen psychosozialen Belastungen ausgesetzt. Um Versorgungs- und Präventionsbedarfe dieser Bevölkerungsgruppe niedrigschwellig und diversitätssensibel zu decken, werden vermehrt Peer-Ansätze verfolgt. Der vorliegende Beitrag informiert den Diskurs über die (We...iter-)Entwicklung und Implementierung von entsprechenden Angeboten für geflüchtete Menschen in Deutschland, indem zentrale Erkenntnisse aus der Prozessevaluation des präventiven Peer- Ansatzes „Mind-Spring“ (MS) nach Pilotierung in einem kommunalen Setting vorgestellt und diskutiert werden.
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Glob Heart . 2020 Oct 13;15(1):69. doi: 10.5334/gh.891.
Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
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Cutaneous leishmaniasis (CL) is a neglected infectious endemic disease that is transmitted through the bite of a vector insect (sandfly) of the Lutzomyia genus,typical of rural geographical territories, and causes disfiguring skin ulcers and disabilities. It is estimated that CL affects between 600 ...000 and 1 000 000 people a year around the world, mainly in the America s, the Mediterranean basin, the Middle East and Central Asia. Eighteen of the 21 countries that make up the Latin American (LA) region are considered endemic areas for this neglected tropical disease. Colombia is one of the countries that reports the majority of global cases with 6161 in 2020 and has the second highest number of cases in the Americas, after Brazil.
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This resource mapping contains signposting and direct links to a range of resource sites and content online; this includes information about the main sources for trustworthy information about the pandemic; sites for e-learning; organisations providing COVID-19 communication response guidance and too...ls; and sites providing downloadable materials such as factsheets and posters and access to material such as videos and audio.
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THELANCETID-D-16-00800 S1473-3099(16)30318-8
TB remains one of the world’s deadliest infectious diseases, second only to COVID-19, and drug-resistant TB strains are still a major concern. In the fight against TB, urgent investment is critical, especially in the context of the ongoing pandemic.
In this course you will examine the interconnections between poverty, development and violent conflict. This is one of seven Medical Peace Work courses.
Acta Trop. 2020 Mar:203:105289. doi: 10.1016/j.actatropica.2019.105289
The role of malacological surveys to identify potential transmission sites for schistosomiasis control in this era of
mass drug administration have received little attention. In that context, the present study was conducted to
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determine the abundance, identity and disease transmission potential of intermediate host snails for intestinal
schistosomiasis on Ijinga Island, north-western Tanzania.
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Chromoblastomycosis (CBM), represents one of the primary implantation mycoses caused by melanized fungi widely found in nature. It is characterized as a Neglected Tropical Disease (NTD) and mainly affects populations living in poverty with significant morbidity, including stigma and discrimination.
Principles and Target Product Criteria. Roadmap January 12, 2015