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The aim of this protocol is to support the conduct of entomological comparative efficacy assessments for vector control products and the associated non-inferiority analysis. This evidence is used to inform discussions within the guidelines development context as to whether a new vector control prod
...
uct should be considered as covered by one or more existing WHO recommendations or not. Alternatively, the evidence may inform the extension of an existing WHO recommendation or the development of a new one, provided that non-inferiority is demonstrated
more
Video
This WHO video presents updated recommendations on two new types of insecticide-treated nets (ITNs) designed to combat mosquito resistance: nets containing either pyrethroid and chlorfenapyr or pyrethroid and pyriproxyfen. The video highlights the improved effectiveness of these nets compared to sta
...
ndard nets and emphasises the importance of their universal use in malaria-endemic areas, particularly for pregnant women and young children where supplies are limited.
more
This WHO guidance outlines reactive strategies to interrupt malaria transmission in areas nearing elimination or to prevent re-establishment, triggered by confirmed cases.
Vector control, alongside case management, remains the most effective approach to controlling and eliminating malaria. Key interventions, such as indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs), have significantly reduced malaria transmission in many African countries. This
...
has enabled some countries to transition from the control phase to the elimination phase.
more
The purpose of the guideline is to provide information to stakeholders on the necessary requirements for a complete prequalification dossier for insecticide-treated nets (ITNs). Its aim is to establish the baseline for dossier requirements which are necessary to assess ITN products for the purposes
...
of prequalification, describe the data requirements for fulfilling each dossier module, and to provide standardized information for applicants and testing facilities generating data for ITN prequalification dossiers. The document is supported by implementation guidance documents which provide specific information and considerations for how applicants may approach the generation of supporting information and compilation of a complete product dossier.
more
In recent decades we have seen progressive changes to global climate patterns caused by anthropogenic impacts on the environment. These are likely to directly and indirectly affect human health, and are projected to continue and potentially
acceler
...
ate into the future. Neglected tropical diseases (NTDs) and malaria are potentially particularly sensitive to these changes as they
are prevalent amongst vulnerable populations
in countries expected to experience the greatest
environmental change in the coming decade.
more
Countries that have achieved at least 3 consecutive years of zero indigenous cases are eligible to apply for a WHO certification of malaria-free status.
Available in English, French an Spanish. The Malaria Threats Map is an interactive data platform which provides a geographic overview of the status of the 4 biological threats to malaria control and elimination
This document outlines key health messages for children and their caregivers, with a focus on the prevention and early treatment of common illnesses. Topics covered include malaria, diarrhoea, malnutrition, respiratory infections, intestinal worms,
...
HIV/AIDS and accident prevention. The importance of insecticide-treated nets, oral rehydration salts (ORS), breastfeeding, immunisation, hygiene, access to clean water, deworming and emotional care for child development is also emphasised. The practical advice provided helps families to create safer and healthier environments, and to recognise when medical help is needed.
Accessed on 15/07/2025.
more
The Malaria Prevention Campaign, launched in Oromia Region of Ethiopia recognized communities for taking specific actions to combat malaria. The focus of the campaign was around small, doable actions that families carry out to protect themselves against malaria. The community volunteers under direct
...
ion from the Community Mobilization Committee (CMC) energized and supported their communities, families, and schools to take the actions necessary to prevent malaria.
more
This training module on malaria case management has been developed to support the staff involved in malaria control and elimination programmes in the effective organization of malaria diagnosis and case management services
This video explores the impact of rapid urbanisation on the transmission of malaria, highlighting that, although the burden of malaria remains highest in rural areas, the majority of people in malaria-endemic countries will soon reside in urban areas. It explains how well-planned urbanisation can re
...
duce malaria by improving access to healthcare and infrastructure, whereas rapid, unplanned urban growth may increase the risk, particularly among the urban poor.
more
Offering additional pre-exposure prophylaxis (PrEP) choices has the potential to increase uptake and effective use of PrEP, and of HIV prevention overall, as it allows people to choose a method that they prefer.
In this guideline, WHO recommends an offering long-acting injectable lenacapavir (LEN
...
) as an additional HIV prevention choice, as part of combination HIV prevention approaches. LEN, administered twice a year as PrEP, has been shown to be highly effective at reducing the risk of HIV acquisition. In this guideline, WHO also recommends using HIV rapid diagnostic tests (RDTs) for individuals initiating or continuing long-acting injectable PrEP, such as LEN and long acting injectable cabotegravir (CAB-LA). Flexible HIV testing approaches are essential for ensuring that testing does not become a barrier to accessing or continuing PrEP, including long-acting injectable options.
more
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex B
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex C
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex D
Mathematical modelling of lenacapavir: landscaping review on impact and cost–effectiveness
recommended
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex E
