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1
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
HIV-1 drug resistance (HIVDR) genotyping is an essential component of the WHO global HIVDR surveillance strategy. Plasma “gold standard” specimen type for HIVDR genotyping, but its use may not be feasible in rural, remote areas in low-
...
and middle-income countries, since preparing and storing it require personnel and laboratory infrastructure that are often lacking. An alternative specimen type is dried blood spots (DBS), which can be made without special laboratory processing. DBS are more easily transported than plasma because they can be shipped at ambient temperature as non-hazardous materials using regular mail or courier services.
3rd edition
more
The purpose of this guide is to provide updated clinical guidance on TB/HIV, with an emphasis on diagnostic aspects—including new techniques—as well as current treatment, while maintaining a public health approach. By compiling
...
and consolidating the latest World Health Organization recommendations on the subject into a single guide, the aim is to create a reference and consultation document that is frequently used, and that unifies and standardizes the comprehensive management of TB/HIV co-infection in healthcare facilities based on the principle of “two diseases, one patient.” It also seeks to support the updating of national standards and guidelines on co-infection and to complement the coordinated work that must exist between TB and HIV prevention and control programs at all levels, within the framework of the twelve internationally recommended TB/HIV collaborative activities.
more
Chapter 1 of the WHO manual for male circumcision as an HIV prevention strategy
provides an overview of how medical male circumcision (VMMC) can reduce the risk of female-to-male HIV transmission.
...
It explains that VMMC is an effective and safe risk-reduction method that, according to three randomized controlled trials, reduces HIV acquisition by approximately 60%. The chapter highlights that VMMC should be offered as part of a combination prevention approach, alongside other strategies like safer sex education and condom use, to address concerns about potential behavioral changes.
more
HIV rapid diagnostic test market landscape
recommended
The analysis includes the three most commonly used HIV rapid diagnostic test
(RDT) categories: HIV-only professional use RDTs, dual HIV/syphilis p
...
rofessional use
RDTs, and HIV self-tests (HIVST).
more
Prevention of mother-to-child HIV transmission (PMTCT) has been a success in many respects
but there is still much to do to eliminate mother-to child transmission (MTCT), particularly in low
antiretroviral therapy (ART) coverage areas
...
and in the postnatal phase. The success of PMTCT is
highly dependent on the availability and accessibility of patient-centred care, which enables women
and their families to take informed decisions about their health and the health of their infant. For
this reason, it is recommended to have a patient-centred approach when implementing PMTCT.
PMTCT success is also linked to the partners’ involvement, as well as to community acceptance
of HIV.
more
Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant dia
...
gnosis of HIV: interim guidelines. Supplement to the 2016 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection
WHO/CDS/HIV/18.28
more
Treatment adherence includes starting HIV treatment, keeping all medical appointments, and taking HIV medicines exactly as prescribed. For people w
...
ith HIV, treatment adherence is key to staying healthy.
more
PLoS One 20(5): e0319807. https://doi.org/10.1371/journal.pone.031980
The implementation of people-centered, evidence-driven, culturally, and religiously
sensitive program enabled SFH to reach a high number of AP in northern Nigeria. This
helps i
...
mprove equity in access to care by AP. There are specific program areas that need
continuous improvement including strategies to reach MSM to avoid the evolution of
new structural barriers; expansion of PWID programming to optimize all aspects of harm
reduction; and sustained sensitization, education, and awareness creation among AP to
improve uptake of PrEP and other prevention and care services.
more
BHIVA guidelines on antiretroviral treatment for adults living with HIV-1 2022 (2025 interim update)
The purpose of the 2025 interim update of the guidelines was to update our recommendations based on new evidence since the last update, including: (i) incorporating new evidence related to injectable therapy including frequency of viral load monitoring and
...
use of long-acting cabotegravir/rilpivirine in non-virally suppressed people; (ii) removal of abacavir from first-line recommendations for most and a recommendation to switch away from abacavir where clinically appropriate; (iii) removal of the CD4 caveat for first-line dolutegravir/lamivudine use; (iv) updated recommendations for people with NRTI resistance. These changes, with the supporting evidence, are highlighted in green.
more
This UNAIDS 2024 report brings together new data and case studies which demonstrate that the decisions and policy choices taken by world leaders this year will decide the fate of millions of lives
...
and whether the world’s deadliest pandemic is overcome.
more
This user friendly and succinct course, provides learners with the opportunity to have a basic understanding of HIV and its treatment. It is usefu
...
l as an introductory course for those who are caring for people living with HIV or anyone who is interested to acquire knowledge in this field.
more
Demographic and socioeconomic data Progress towards HIV testing and treatment cascade targets by 2025 (2023) Health sector cascade (2023) Estimat
...
ed number of people newly infected with HIV
more
HIV testing programmes need to ensure that all clients who test for HIV are provided with correct diagnoses. The accuracy of HIV testing is critica
...
l to prevent misdiagnosis, as the consequences of giving an incorrect test result can be serious for clients, HIV testing services, HIV programmes and public health.
With the evolution of global HIV epidemiology, HIV testing approaches must also evolve to maintain accuracy and efficiency in population-level diagnosis. Reports suggest that misdiagnosis of HIV status may occur when suboptimal testing algorithms and out-of-date testing strategies are used. As a result of changing epidemiology and declining HIV positivity in testing, WHO recommends all countries use a standard three-test strategy to ensure a PPV of at least 99%, minimizing false-positive misdiagnosis. The WHO-recommended HIV testing strategy, along with quality assurance measures such as retesting to verify a positive diagnosis prior to initiation of HIV treatment, is cost-effective as it prevents misdiagnosis and unnecessary initiation of costly lifelong treatment.
This implementation guide provides practical advice on switching to a three-test strategy and instituting other measures that can help national HIV programmes deliver high-quality, accurate HIV testing services and ensure that misdiagnosis is minimized.
more
Int. J. Environ. Res. Public Health 2022, 19(4), 2359; https://doi.org/10.3390/ijerph19042359.
With improved access to antiretroviral treatment (ART), adults with HIV live longer to reach older age. The number of older adults living with
...
HIV is increasing steadily, giving rise to a new population of interest in HIV research and for invigorated considerations in health service delivery and policy. We analysed the profile of comorbidities in older people (50 years and older) living with HIV in South Africa.
more
Case Study on Improving HIV Testing and Services for Children Orphaned or made Vulnerable by HIV (OVC)
HIV drug resistance strategies focus on prevention through adherence and treatment optimization, surveillance to monitor resistance trends, and inn
...
ovation in new drugs and diagnostics. Key approaches include implementing national action plans, strengthening laboratory capacity for monitoring, and providing comprehensive care, especially for vulnerable populations
more
