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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Update on COVID-19 vaccination in Syria

World Health Organization WHO; Eastern Mediterranean Region (2021) C_WHO

22 April 2021

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WHO Country Cooperation Strategy 2017-2021, Zambia

World Health Organization WHO, Regional Office for Africa (2017) C_WHO

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Health Care Waste Management Manual, Fourth Edition

Department of Health Philippines (2020) CC

This document shall serve as the most comprehensive set of guidelines on the safe management of waste generated from heath care activities in the country. It incorporates the requirements of all Philippine laws and regulations governing HCWM and is designed for the use of individuals, public and pri... more

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Water, sanitation, hygiene and habitat in prisons: supplementary guidance

International Committee of the Red Cross ICRC (2012)

A practical handbook covering the architecture, engineering, design and operation of prisons. It is intended for all ICRC delegates working in places of detention, whether they have extensive practical experience or are new to the field.

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Guidance for health sector assessment to support the post-disaster recovery process

United Nations agencies, the World Bank and the European Commission (2010)

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LACRO Zika Virus Humanitarian Situation Report No.2, 1 April 2016

UNICEF (2016) C1

External Link

Minimum technical standards and recommendations for reproductive, maternal, newborn and child health care for emergency medical teams

World Health Organization WHO; Institutional research information system iris (2021) C_WHO

World Health Organization. (‎2021)‎. Minimum technical standards and recommendations for reproductive, maternal, newborn and child health care for emergency medical teams. World Health Organization.

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Afghanistan: Agricultural livelihoods and food security in the context of COVID-19

Food and Agriculture Organization of the United Nations FAO (2021) CC

This survey of agricultural livelihoods and food security in the context of the impact of coronavirus disease 2019 (COVID-19) and other shocks was undertaken during February 2021 by the Food and Agriculture Organization of the United Nations (FAO) in 1 380 villages within 129 districts of 20 provinc... more

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Ensuring health security in the African region: Emergency preparedness and response flagships progress report #4

World Health Organisation (WHO) (2022) C_WHO

The World Health Organization Regional Office for Africa (WHO AFRO), in accordance with recommendations from various WHO committees, has developed three flagship initiatives to support Member States in the African region to prepare for, detect and respond to public health emergencies. They are the r... more

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Point-of-use fortification with micronutrient powders (mnp)improving the nutrition of infants and young children aged 6-23 months (Healthcare Providers)

Ministry of Health, Kenya (2020) C1

The micronutrient powders will be distributed at the health facilities where instructions on use will be provided by Health Care Providers. Community Health Volunteers will educate, counsel, and mobilize caregivers at the community level to visit health facilities for nutrition assessment and provis... more

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Pandemic influenza preparedness and response WHO guidance document. Extract Phase 5-6 Pandemic

World Health Organization WHO (2009) C_WHO

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Ebola virus disease preparedness strengthening team Mali country visit 20-24 October 2014

World Health Organization (2014)

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Managing WHO Humanitarian Response in the Field

World Health Organization (2008)

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Real Time Evaluation of the Ebola Control Programs in Guinea, Sierra Leone and Liberia. Annexes

International Federation of Red Cross And Red Crescent Societies (2015)

External Link

Effective Media Communication during Public Health Emergencies. Handbook and Field Guide
recommended

World Health Organization WHO (2005) C_WHO

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Security to go: a risk management toolkit for humanitarian aid agencies
recommended

Davis, J.; and L. Reilly European Interagency Security Forum (EISF) (2015) C1

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Flash Appeal for COVID-19 Mozambique, May - December 2020

UN Office for the Coordination of Humanitarian Affairs (2020) CC

The first case of COVID-19 was reported in Mozambique on 22 March 2020. As of 26 May, Mozambique had 194 confirmed cases of COVID-19, of which 168 were locally transmitted. The country’s capital, Maputo, and the province of Cabo Delgado are currently the epicentres of the outbreak in Mozambique, w... more

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WHO policy brief: Maintaining infection prevention and control measures for COVID-19 in health care facilities, 14 September 2022

World Health Organization WHO (2022) C_WHO

This document aims to encourage countries to develop and implement policies to maintain and strengthen IPC programmes and measures in health care facilities in the context of the current ongoing transmission of the SARS-CoV-2, with recognition that epidemiological trends may vary and the risk of tra... more

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Sphere standards in national humanitarian response. Engaging with National Disaster Management Authorities

The Sphere Project (2016)

The Sphere standards in national humanitarian response discussion paper sets out to understand and describe opportunities for adapting international humanitarian standards to a regional, national or local level in preparing for, or responding to a disaster. The paper, which includes case studies and... more

Effective Media Communication during Public Health Emergencies. Handbook and Field Guide recommended

Security to go: a risk management toolkit for humanitarian aid agencies recommended

Effective Media Communication during Public Health Emergencies. Handbook and Field Guide
recommended

Security to go: a risk management toolkit for humanitarian aid agencies
recommended