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Chagas Clinical Research Platform Newsletter

Drugs for Neglected Diseases Initiative DNDi Latin America (2022) CC
To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Chagas disease. The patient-centred platform aims to f... more
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Global report on neglected tropical diseases 2024: executive summary

World Health Organization WHO (2024) C_WHO
Three full years have passed since the launch of the road map for neglected tropical diseases 2021–2030. Data on progress begin to provide insights into the prospects of attaining the 2030 targets.
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New generations free of HIV, syphilis, hepatitis B and Chagas disease in the Americas 2018

M. Alonso González; M. B. Mello; L. Sereno; et al. Pan American Health Organization; World Health Organization (Americas); Unicef (2019) C_WHO
- EMTCT Plus
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First meeting of the network on Buruli ulcer PCR laboratories in the WHO African Region Centre Pasteur du Cameroon, Yaoundé, 21–24 October 2019

World Health Organization WHO (2020) CC
Research to develop point-of-care tests is in progress. Treatment of Buruli ulcer comprises 8 weeks of combined antibiotics (rifampicin and clarithromycin). Complementary therapies such as wound care, skin graft and prevention of disability are needed in some cases to ensure full recovery. The targ... more
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Première réunion du réseau de laboratoires PCR pour l’ulcère de buruli dans la région africaine de l’OMS, Centre Pasteur du Cameroun, Yaoundé, 21–24 octobre 2019

Organisation Mondiale de la Santé OMS (2020) CC
L’ulcère de Buruli, une infection causée par Mycobacterium ulcerans, touche plus de 33 pays dans le monde, mais un peu moins de la moitié seulement de ces pays communiquent régulièrement des données sur la maladie à l’OMS.
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Vector control and the elimination of gambiense human African trypanosomiasis

World Health Organization WHO (2022) C_WHO
The main purpose of the meeting was to review tsetse control tools, activities and their contribution to the elimination of gHAT and the monitoring thereof. Seven endemic countries provided reports on recent and ongoing vector control interventions at the national level (Angola, Cameroon, Côte d’... more
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Global vector control response 2017–2030

World Health Organization (WHO) (2017) C_WHO
The Global vector control response 2017–2030 (GVCR) provides a new strategy to strengthen vector control worldwide through increased capacity, improved surveillance, better coordination and integrated action across sectors and diseases.
In May 2017, the World Health Assembly adopted resolutio... more
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Global vector control response 2017–2030: A strategic approach to tackle vector-borne diseases. Summary

World Health Organization (WHO) (2017) C_WHO
Mosquitoes, flies, bugs and other vectors transmit viruses, parasites and bacteria that infect millions of people globally. They cause many diseases, including malaria, dengue, leishmaniases, Chagas disease and Zika virus disease. The World Health Organization (WHO) has developed a new strategy to... more
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Cutaneous Leishmaniasis: Urgent need to develop more effective and user-friendly point-of-care diagnostic tools

DNDi redeLEISH (2022) CC
Leishmaniasis is a complex vector-borne disease involving in its transmission several species of protozoan parasites called Leishmania, a wide variety of animal reservoirs and phlebotomine sandflies vectors. Cutaneous Leishmaniasis (CL) is the most common form of the disease, and its clinical manife... more
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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data plat

Maguire, B.J.; Dahal, P.; Rashan, S. et al. PLOS Neglected Tropical Diseases (2021) CC
PLoS Negl Trop Dis 15(8): e0009697. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses t... more
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Improved school-based deworming coverage through intersectoral coordination in Kenya

World Health Organization WHO (2013) C_WHO
This report outlines the coordination and partnership between two key ministries (Education and Public Health) in Kenya, other line ministries, the private sector, NGOs and the community in implementing the first phase of a sub-national school-based deworming exercise. The areas targeted included Co... more
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The Expanded Special Project for Elimination of Neglected Tropical diseases — ESPEN

World Health Organization WHO (2023) C_WHO
While virtually unheard of in developed countries, NTDs are a group of medically diverse parasitic and bacterial infectious diseases common in tropical and subtropical areas. NTDs affect more than 1.5 billion people annually, causing death, blindness, disfigurement, chronic pain, cognitive impairmen... more
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ENVISION WEBINAR: La boite outils de l'IEC et la mobilisation sociale

USAID, RTI International and Sightsavers (2023) C2
This webinar provides an overview of the new IEC & Social Mobilization NTD Tool Kit, which leads users through a step-by-step process to systematically review, revise, develop and adapt current IEC materials and social mobilization approaches towards stronger, evidence-based practices in support of ... more
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An integrated, Sustainable Framework to Elimination of Communicable Diseases in the Americas. Concept Note

Pan American Health Organisation (PAHO) (2019) C_WHO
The objective of this concept note and the framework it outlines is the elimination of a group of CDs and the negative health effects they generate, which together create a tangible burden on affected individuals, their families and communities, and on health care systems throughout the Region. Thou... more
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DNDi Plano Estratégico 2021–2028 Resumo Executivo

DNDi - Drugs for neglected diseases initiative (2023) C2
A Iniciativa Medicamentos para Doenças Negligenciadas (DNDi) é uma organização internacional sem fins lucrativos que disponibiliza medicamentos seguros, eficazes e acessíveis para doenças negligenciadas, desde o laboratório até sua chegada às mãos das populações mais vulneráveis do mund... more
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DNDi Plan Stratégique 2021-2028 Résumé

DNDi - Drugs for neglected diseases initiative (2023) C2
L’initiative Médicaments contre les Maladies Négligées (DNDi) est une organisation internationale à but non lucratif spécialisée dans la recherche, le développement et la mise à disposition de traitements sûrs, efficaces et abordables aux patients les plus négligés.
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DNDi Plan Estratégico 2021-2028 Resumen ejectivo

DNDi - Drugs for neglected diseases initiative (2023) C2
La Iniciativa Medicamentos para Enfermedades Olvidadas (DNDi) es una organización internacional sin fines de lucro que proporciona tratamientos seguros, eficaces y asequibles para los pacientes más desatendidos, desde el laboratorio hasta su llegada a las manos de las poblaciones más vulnerables ... more
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Collaboration entre le secteur WASH et le secteur de la santé
recommended

Organisation Mondiale de la Santé OMS (2019) C_WHO
GUIDE PRATIQUE À L’INTENTION DES PROGRAMMES DE LUTTE CONTRE LES MALADIES TROPICALES NÉGLIGÉES This toolkit provides step-by-step guidance to NTD programme managers and partners on how to engage and work collaboratively with the WASH community to improve delivery of water, sanitation and hygien... more
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WASH and Health working together: a ‘how-to’ guide for neglected tropical disease programmes
recommended

World Health Organization WHO (2023) C_WHO
2nd edition. This toolkit provides step-by-step guidance to NTD programme managers and partners on how to engage and work collaboratively with the WASH community to improve delivery of water, sanitation and hygiene services to underserved population affected by many neglected tropical diseases. The ... more
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Ending the neglect to attain the sustainable development goals: a rationale for continued investment in tackling neglected tropical diseases 2021–2030

World Health Organization (WHO) (2022) C_WHO
This document sets out, therefore, to explain the socioeconomic value of investing in the fight against NTDs and highlights priorities for global investment attention. Our work was guided by the need not only for additional funding and funders but also for the need to understand the current funding... more