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Evidence summary: systematic review of oral fexinidazole as first line treatment for rhodesiense Human African Trypanosomiasis

World Health Organization WHO (2024) C_WHO
Guidelines for the treatment of human African trypanosomiasis. Web Annex A. Commissioned by WHO Cochrane Response
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PICO questions, EtD tables, GDG recommendations

World Health Organization WHO (2024) C_WHO
WHO Guidelines for the Treatment of Human African Trypanosomiasis. Web Annex B
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Criteria and procedures for the verification of elimination of transmission of "T. b. gambiense" to the human population in a given country

World Health Organization WHO (2023) C_WHO
Having established the goal of eliminating transmission of gambiense human African trypanosomiasis (g-HAT) to humans, the HAT-e-TAG considered which elements should be developed to assess this goal.
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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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The Atlas of HAT

World Health Organization WHO (2008) C_WHO
In February 2008, WHO launched the Atlas of HAT as a collaborative initiative with the Food and Agriculture Organization of the United Nations (FAO), within the framework of the Programme Against African Trypanosomosis (PAAT). The Atlas database is built by the systematic collection of information a... more
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Number of new reported cases of human African trypanosomiasis (T.b. rhodesiense)

World Health Organization WHO (2025) C_WHO
The Global Health Observatory
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Number of reported cases of human African trypanosomiasis (T.b. gambiense)

World Health Organization WHO (2025) C_WHO
The Global Health Observatory
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Human African trypanosomias: Number of new reported cases of human African trypanosomiasis (T.b. gambiense) 2023

World Health Organization WHO (2023) C_WHO
Database with maps and country-specific numbers
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Neutralizing monoclonal antibody cocktail REGN-EB3 for Ebola virus disease (EVD)
recommended

World Health Organization WHO (2022) C_WHO
Guidance for health care workers. Both the REGN-EB3 and mAb114 are recommended for use in EVD. The two drugs should not be given together. The choice of which monoclonal antibody to use depends on availability, including emerging information about effectiveness.
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Malawi - HIV Country Profile 2024

World Health Organization WHO (2024) C_WHO
Demographic and socioeconomic data Progress towards HIV testing and treatment cascade targets by 2025 (2023) Health sector cascade (2023) Estimated number of people newly infected with HIV
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Trichiasis surgery for trachoma
recommended

World Health Organization WHO (2024) C_WHO
3rd edition
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Diagnostic target product profiles for trachoma surveillance
recommended

World Health Organization WHO (2024) C_WHO
Trachoma is the leading infectious cause of blindness worldwide. In April 2023, it was a public health problem in approximately 40 countries, with an estimated 116 million people at risk and 1.5 million people affected by the late blinding stage of the disease (1). About 84% of those at risk of tr... more
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Eliminating Trachoma: Accelerating Towards 2020

World Health Organization WHO (2020) C_WHO
Trachoma is the world’s leading infectious cause of blindness. It is one of 18 neglected tropical diseases (NTDs) that affect over one billion of the world’s poorest people.
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Plague manual: epidemiology, distribution, surveillance and control Chapter 6-7

World Health Organization WHO (1999) C_WHO