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Research priorities for Chagas disease, human African trypanosomiasis and leishmaniasis

World Health Organization WHO (2012) C_WHO
This report provides a review and analysis of the research landscape for three diseases – Chagas disease, human African trypanosomiasis and leishmaniasis – that disproportionately afflict poor and remote populations with limited access to health services. It represents the work of the disease re... more
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Snakebite envenoming: a strategy for prevention and control: executive summary World Health Organization

World Health Organization WHO (2019) C_WHO
Snakebite envenoming is a neglected tropical disease (NTD) that is responsible for enormous suffering, disability and premature death on every continent. As over 5.8 billion people are at risk of encountering a venomous snake, it is not surprising but no less tragic that almost 7400 people every da... more
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Wiping out Trachoma from Nepal – How Nepal eliminated trachoma as a public health problem

World Health Organization WHO (2018) C_WHO
Wiping out Trachoma from Nepal – How Nepal eliminated trachoma as a public health problem WHO - 2018
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Guide to introducing human rabies vaccine into national immunization programmes: Handbook

World Health Organization WHO (2022) C_WHO
Rabies is fatal, vaccine-preventable disease responsible for an estimated 59,000 human deaths each year. Most cases are transmitted by dogs, and most deaths occur in underserved populations in Africa and Asia. Approximately 40% of deaths occur in children.
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Laboratory techniques in rabies

Rupprecht, C.; Fooks, A,; Abela-Ridder, B. World Health Organization WHO (2018) C_WHO
Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ... more
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How to Investigate Antimicrobial Use in Hospitals: Selected Indicators

USAID; Strengthening Pharmaceutical Systems (2008) C1
The purpose of this manual is to define a limited number of indicators that will objectively describe the management and use of antimicrobials in hospitals and to provide tools and step-by-step instructions for designing and carrying out an assessment of antibiotic use and management in hospitals. T... more
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A WHO Guide to the Implementation of the WHO Multimodal Hand Hygiene Improvement Strategy

World Health Organization WHO (2009) C_WHO
Health care-associated infection (HCAI) places a serious disease burden and has a significant economic impact on patients and health-care systems throughout the world. Yet good hand hygiene, the simple task of cleaning hands at the right times and in the right way, can save lives. World Health O... more
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Report of the 4TH Global Scientific Meeting on Trachoma

World Health Organization WHO (2018) C_WHO
Trachoma is the leading infectious cause of blindness (2). It is characterized by repeated conjunctival infection with particular strains of Chlamydia trachomatis. This scars the conjunctivae and, in some cases, leads to trichiasis with or without entropion. The abrasive action of eyelashes can d... more
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Towards a Human Rights-Based Approach to Migration: Training Guide

UN Office of the High Commissioner for Human Rights OHCHR (20023) CC
This training guide is designed to enable participants to understand the human rights perspective on migration, and how human rights laws and standards can be operationalized to make migration safer and an empowering experience for all. It provides an introduction to related principles and issues an... more
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The World Medcines situation 2011 Rational use of Medicines

World Health Organization WHO (2011) C_WHO
Millennium Development Goal 8E aims for affordable access to essential medicines. Essential medicines, as defined by WHO, are those that “satisfy the health-care needs of the majority of the population” and that should therefore “be available at all times in adequate amounts”. However, there... more
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Mission Rabies Annual Report 2018

Mission Rabies (2018) CC
2018 has been one of the most successful years ever for Mission Rabies. We are on the cusp of having almost vaccinated one million dogs in global rabies hotspots, we’ve educated over two million children and we’re seeing a dramatic reduction in both human and canine rabies in all our flagship... more
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WHO interim guidelines for the treatment of gambiense human African trypanosomiasis

World Health Organization WHO (2019) C_WHO
This document focuses on the management of patients affected by gambiense HAT and constitutes an update to the WHO therapeutic guidance issued in 2013. The main changes in recommendations concern the criteria and methods for deciding the treatment among the new set of therapeutic options and the pa... more
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Target product profile for readers of rapid diagnostic tests

World Health Organisation (WHO) (2023) C_WHO
Lateral-flow rapid diagnostic tests (RDTs) continue to play a vital role in global health in the management and diagnosis of infectious diseases, including malaria, HIV and COVID-19. Visually interpreted RDTs, more than any other class of diagnostics, fulfil WHO’s ASSURED criteria,1 enabling their... more
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Developing New Diagnostic Tests for Human African Trypanosomiasis - Current status and future plans

HAT & OND Team Foundation for innovative new diagnostics FIND (2013) C2
FIND and Standard Diagnostics (SD) have developed a lateral flow rapid diagnostic test (RDT) to screen for T.b. gambiense HAT that is cheap and easy to use. The tests are packed individually and are stable at 40°C for up to 25 months; they are performed on fresh blood obtained from a finger prick... more
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Gender equality and women’s empowerment in the world of work in fragile, conflict and disaster settings

International Labour Organization (2022) CC
Conflicts and disasters, including pandemics, affect women and men in all their diversity differently, and women and girls often suffer the most. Crisis-related hardships combine and compound pre-existing disadvantages, for example, they often cause women’s working conditions to worsen while incre... more
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Accelerating towards human African trypanosomiasis elimination: Issues and opportunities

Ozioko ,KU.; Okoye, CI.; Obiezue, RN.; Idika, IK.; Awudu, RA.; Ezewudo, BI.; Ezea, CO. (2019) CC
Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and transmitted by tsetse flies. Progress made in HAT ... more
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WHO Eritrea 2022 Annual Report

World Health Organisation (WHO) (2023) C_WHO
During the year 2022, COVID-19 continued to be a significant challenge in Eritrea as in many other countries across the world. As COVID-19 devastated communities around the world, WHO worked with the MoH to strengthen the National and Sub-National health systems in order to meet community needs and ... more
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Communicating with caregivers about the Human Papillomavirus vaccination

World Health Organisation (WHO) (2023) C_WHO
This training module is designed to equip health workers (HWs) with knowledge, skills, confidence and resources to help them in their role to recommend the Human Papillomavirus (HPV) vaccine.
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Framework for Environmental and Social Management

Food and Agriculture Organization of the United Nations FAO (2023) CC
The Food and Agriculture Organization of the United Nations (FAO) launched a new Framework for Environmental and Social Management (FESM) to ensure that both people and the environment are protected from any potential impacts of FAO programmes and projects. “This Framework ensures that our proj... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more