The conditionality of this recommendation is largely driven by the current higher unit cost of pyrethroid-PBO ITNs compared
to pyrethroid-only LLINs and therefore the uncertainty of their cost-effectiveness. Furthermore, as PBO is less wash-resistant
than pyrethroids, its bioavailability declines ...faster over the three-year estimated life of an ITN; therefore, the added impact of
pyrethroid-PBO ITNs over that of pyrethroid-only LLINs may decline over time. The evidence comes from two sites in
eastern Africa with pyrethroid resistance and not from other geographies where transmission levels and vector characteristics
may vary. PBO acts by inhibiting certain metabolic enzymes, primarily oxidases, and so are likely to provide greater protection
than pyrethroid-only LLINs where mosquitoes display mono-oxygenase-based insecticide resistance mechanisms.
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The report reflects on the trends, achievements and challenges in global health over the past decade during which Dr Margaret Chan has been Director-General of WHO. It discusses the role of WHO in dealing with such issues as the rise of noncommunicable diseases, leaps in life expectancy, and emergin...g threats like climate change and antimicrobial resistance.
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Compiled by Tin Geber for HIVOS. London, March 2018
UN GUIDE POUR L’APPROVISIONNEMENTEN MÉDICAMENTS/ A guide for drug supply
Bochure in English and French
Organizing and Delivering High Quality Care for Chronic Noncommunicable Diseases in the Americas
Countdown to zero
2011- 2015
What countries need: Investments needed for 2010 targets
Available in English, French, Spanish, Russian, Chinese, Arabic and Portugues
Overall, harmonisation and innovation should be the
focus of the future direction of DAH and the creation of
a healthy global community. The world needs all hands
on deck if it were to move towards achieving the SDGs,
addressing global health inequalities and improving the
welfare of the global... population, while ensuring that no
one is left behind.
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This report presents the findings from the Community Based Volunteers Skill Audit Survey that was carried out in 11 districts in Zambia as part of the Millennium Development Goal Acceleration Initiative.