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1
Minimizing risk of developing antibiotic resistance and aquatic ecotoxicity in the environment resulting from the manufacturing of human antibiotic.
The Standard, facilitated by BSI Standards Limited (BSI), provides clear guidance to manufacturers in the
...
global antibiotic supply chain to ensure that their antibiotics are made responsibly, helping to minimize the risk of AMR in the environment.
more
During the first year of the Covid-19 pandemic, the world’s economy slowed. Yet, the global annual average particulate pollution (PM2.5) was largely unchanged from 2019 levels. At the same time, growing evidence shows air pollution—even when exp
...
erienced at very low levels—hurts human health. This recently led the World Health Organization (WHO) to revise its guideline for what it considers a safe level of exposure of particulate pollution, bringing most of the world—97.3 percent of the global population—into the unsafe zone. The AQLI finds that particulate air pollution takes 2.2 years off global average life expectancy, or a combined 17 billion life-years, relative to a world that met the WHO guideline. This impact on life expectancy is comparable to that of smoking, more than three times that of alcohol use and unsafe water, six times that of HIV/AIDS, and 89 times that of conflict and terrorism.
more
Ocean plastic pollution has reached crisis level: every minute, more than an entire garbage truck of plastic makes its way into the world’s oceans—roughly 11 million metric tons annually. While plastic waste presents an immediate threat to marine wildlife and ecosystems, this
...
global challenge also has implications for major industries such as fishing and tourism, impacting the livelihoods of millions of people. The drivers and impacts of ocean plastic pollution also contribute to global challenges in food security, human health, and climate change.
more
This Joint Evaluation of the Protection of the Fundamental Rights of Refugees during the COVID-19 Pandemic was commissioned under the auspices of the COVID-19 Global Evaluation Coalition. The evaluation examines the effectiveness of international co
...
operation and the combined response of host states, United Nations (UN) system agencies, and non-governmental and civil society organisations including refugee-led organisations in ensuring the protection of the rights of refugees during the global pandemic.
more
This is the first edition of Empiric Antibiotic Guidelines, as a guidance to all medical practitioners at North Okklapa General & Teaching Hospital.
Antibiotics are critical in the management of infection and can have a significant impact in reducing morbidity and mortality. Emerging antimicrobia
...
l resistance has been identified as global challenge by the World Health Organization. Careful use of antibiotics targeted to likely pathogens is an important strategy in combating development of antimicrobial resistance.
more
Achieving universal access to WASH in health care facilities requires political will and strong leadership at both national and facility levels, but is highly cost-effective, and would yield substantial health benefits. A global analysis estimated
...
that universal basic WASH services in health care facilities could be achieved in 46 least developed countries (LDCs) by 2030 for less than US$10 billion, which represents additional expenditures of less than US$1 per person per year.
more
This document sets out, therefore, to explain the socioeconomic value of investing in the fight against NTDs and highlights priorities for global investment attention. Our work was guided by the need not only for
additional funding and funders but
...
also for the need to understand the current funding climate, in which value for money and the efficient use of resources to fill the most critical of gaps are more relevant than ever.
more
PLOS Glob Public Health 2(8): e0000272. https://doi.org/10.1371/journal.pgph.0000272
Sepsis is a major global health problem, especially in sub-Saharan Africa. Improving patient care requires that healthcare providers understand patients’ priorit
...
ies and provide quality care within the confines of the context they work. We report the perspectives of patients, caregivers and healthcare workers regarding care quality for patients admitted for sepsis to public hospitals in Uganda and Malawi. This qualitative descriptive study in two hospitals included face-to face semi-structured interviews with purposively selected patients recovering from sepsis, their caregivers and healthcare workers. In both Malawi and Uganda, sepsis care often occurred in resource-constrained environments which undermined healthcare workers’ capacity to deliver safe, consistent and accessible care. Constraints included limited space, strained; water, sanitation and hygiene (WASH) amenities and practices, inadequate human and material resources and inadequate provision for basic needs including nutrition. Heavy workloads for healthcare workers strained relationships, led to poor communication and reduced engagement with patients and caregivers.
more
The World Health Organization's cholera fact sheet provides essential information about cholera, an acute diarrheal infection caused by ingesting food or water contaminated with Vibrio cholerae bacteria. The disease remains a global public health th
...
reat, particularly in areas lacking safe water and adequate sanitation. While many infected individuals exhibit mild or no symptoms, severe cases can lead to rapid dehydration and death if untreated. Prevention focuses on ensuring access to clean water, proper sanitation, and hygiene practices. Effective treatment primarily involves prompt administration of oral rehydration solutions. The fact sheet also highlights the importance of surveillance, preparedness, and response strategies to control outbreaks.
more
Cholera App
recommended
Introducing the cholera user-friendly app. As part of the effective implementation of the Ending Cholera: A Global Roadmap to 2030, the GTFCC developed a phone-based application containing technical information and practical documents to provide cle
...
ar guidance and up to date information for early detection, monitoring and efficient response to cholera outbreaks. The application is designed for public health professionals from all sectors working in cholera control. The app is designed to be used offline to accommodate those working in the most remote areas.
more
The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels
recommended
The Lancet October 25, 2022DOI:https://doi.org/10.1016/S0140-6736(22)01540-9
As climate change’s impacts continue to accrue, countries are persistently making wrong choices that are harming human health.
A desperate global thirst for fossil fuel
...
s is worsening climate change, leading to more extreme weather events that have hit every continent, led to thousands of deaths, and caused $250+ billion in damage in 2021.
• People 65+ and children <1 experienced 3.7 billion more heatwave days in 2021 than the annual average from 1986–2005.
• Heat-related deaths shot up 68% from 2000–2004 to 2017–2021.
• Climate change is abetting infectious disease transmission, warming coastal waters and leading to the spread of Vibrio bacteria like the one that causes cholera, and expanding the reach of the malaria parasite.
more
Cholera English Information
recommended
MEDBOX Issue Brief 26. Cholera is an acute diarrhoeal infection caused by eating or drinking food or water that is contaminated with the
bacterium Vibrio cholerae. Cholera remains a global threat to public health and is an indicator of inequity and
...
lack of
social development. Researchers have estimated that every year, there are 1.3 to 4.0 million cases of cholera, and 21
000 to 143 000 deaths worldwide due to the infection.
However, cholera remains a neglected and underreported disease. Many cases are not recorded due to limitations in
surveillance systems and fears of potential impact on trade or tourism.
Today cholera affects 47 countries across the globe. Almost every developing country faces cholera outbreaks or
the threat of cholera. Major ongoing outbreaks are being reported from Afghanistan, Bangladesh, Democratic
Republic of Congo, Ethiopia and Nigeria. Major outbreaks are currently in Syria and Haiti.
Therefore, MEDBOX decided to produce issue briefs on cholera and available resources in Arabic, English and
French.
more
The Pandemic Influenza Preparedness (PIP) Framework is a World Health Assembly resolution adopted unanimously by all Member States in 2011. It brings together Member States, industry, other stakeholders and WHO to implement a global approach to pand
...
emic influenza preparedness and response. The Framework includes a benefit-sharing mechanism called the Partnership Contribution (PC). The PC is collected as an annual cash contribution from influenza vaccine, diagnostic, and pharmaceutical manufacturers that use the WHO Global Influenza Surveillance and Response System (GISRS). Funds are allocated for: (a) pandemic preparedness capacity building; (b) response activities during the time of an influenza pandemic; and (c) PIP Secretariat for the management and implementation of the Framework.
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Despite high regional demand for vaccines valued at over US$ 1 billion annually, Africa’s vaccine industry provides only 0.1% of global supply. Vaccine inequity and hoarding at the start of the pandemic, which resulted in delays in obtaining COVID
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-19 doses, stimulated new resolve to address future supply security. In 2021, the AU set a target to produce and supply more than 60% of the vaccine doses on the continent by 2040.
In the last 18 months alone, more than 30 new African manufacturing projects have been announced and estimates indicate that the African vaccine market across all existing and projected novel products could range between US$ 2.8 billion and US$ 5.6 billion by 2040*, demonstrating the potential for a thriving regional industry to emerge.
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The number of people facing acute food insecurity1 is growing at an alarming rate in the European Union (EU) Member States of Central Eastern Europe. COVID-19 and the resulting disruption to global markets, trade, and food supply chains have negativ
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ely affected food security since 2020; now, this has been compounded by the Russian invasion of Ukraine. Women and girls who have been displaced from Ukraine into Hungary are facing tremendous obstacles to their safety and wellbeing, particularly given the link between food insecurity and gender-based violence (GBV). Urgent policy responses and concrete actions are needed to support low-income households and vulnerable communities, particularly women and their families displaced from Ukraine, to stem this growing crisis.
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El mundo se enfrenta a graves consecuencias derivadas de la falta de servicios y tratamientos de salud mental. Todos los países, culturas y comunidades padecen enfermedades mentales y la Organización Mundial de la Salud (OMS) afirma que el 10% de la carga
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global de enfermedad está relacionada con trastornos mentales y neurológicos, así como con el consumo de sustancias. En los países de renta baja y media, más del 75% de las personas con trastornos mentales no reciben ningún tratamiento. En 2020, como resultado de la pandemia mundial, el 93% de los países comunicaron que sus servicios de salud mental se habían detenido o interrumpido (OMS, 2020e). La OMS ha denunciado un incremento del 25% solo en las tasas de depresión y ansiedad durante la pandemia. La Organización para la Cooperación y el Desarrollo Económicos estima que el coste de la depresión y la ansiedad para la economía mundial asciende a 1 billón de dólares estadounidenses al año. Todas las enfermeras tienen una función de prestación de cuidados en materia de salud mental y consumo de sustancias. El CIE aboga firmemente por inversiones en más formación y desarrollo profesional en esta área con el fin de ayudar a las personas y comunidades a lograr el mayor nivel posible de salud, en particular bienestar físico, mental y social.
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In 1997, the Fiftieth World Health Assembly adopted resolution WHA50.29 on the elimination of
lymphatic filariasis as a public health problem. Preliminary guidance from WHO printed in 2011 referred to “verification” as the official process by which the achievements of the
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Global Programme to Eliminate Lymphatic Filariasis (GPELF) would be confirmed. For the sake of harmonization, the terminology now used for elimination of lymphatic filariasis as a public health problem is “validation”. In 2015, the WHO Strategic and Technical Advisory Group for Neglected Tropical Diseases endorsed standardized processes for confirming and acknowledging success for all neglected tropical diseases targeted for eradication, elimination of transmission, or elimination as a public health problem.
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Lymphatic filariasis (LF), a neglected tropical disease, is targeted for global elimination as a public health problem. This article reviews the history of LF control and elimination activities in the countries of the World Health Organization's (WH
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O) Eastern Mediterranean Region (EMR) over the last 2 decades. In 2000, the estimated at-risk population in EMR countries was 12.6 million people, accounting for approximately 1% of the global disease burden. Of the 22 EMR countries, 3 countries (Egypt, Sudan and Yemen) were LF endemic and the disease was suspected in 4 other countries (Djibouti, Oman, Somalia and Saudi Arabia). After almost 2 decades of implementing sustained control and prevention measures, Egypt and Yemen were successfully validated by the WHO as having achieved the elimination criteria in 2017 and 2019, respectively. In 2018, Sudan completed mapping of LF, reaching 26.2% geographical coverage where mass drug administration (MDA) is required and is scaling-up MDA. Extensive epidemiological assessment indicated the absence of LF transmission in the four suspected countries and no MDA required. Challenges faced during the elimination and post-elimination phases are described and discussed
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Microbes like bacteria, fungus and viruses are becoming resistant to medicines like antibiotics. WHO has declared antimicrobial resistance as a global health and developmental threat. How can we stop antimicrobial resistance? Dr Hanan Balkhy explai
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ns in Science in 5
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In collaboration with partners, the government of Ethiopia has successfully developed 10 years Hand Hygiene for All (HH4A) costed national roadmap- a country-wide approach to achieving sustainable and universal hand hygiene. On the occasion of the 2022 Glo
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bal Hand Washing Day event ( Ethiopia is celebrating the event for one month with different sessions), the national HH4A road map launched on the 4th of Nov 2022 in a high-level advocacy event in the presence of higher officials and partners. Action is set mainly on the need for a joint effort to mobilize resources for implementation, monitoring and documenting of lessons and best practices.
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