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Long Acting Muscarinic Antagonists (LAMA) such as tiotropium and glycopyrronium are used in the management of COPD1. They have been shown to improve lung function, quality of life and exercise tolerance. They have also been associated with reduced COPD-related exacerbations, associated hospitalisati
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ons and duration of hospital stay. Both the South African Thoracic Society (SATS) and Global Initiative for Chronic Obstructive Lung Disease (GOLD), guidelines recommend the use of long acting anticholinergic drugs (or long acting beta agonists) in moderate to very severe disease as defined by lung function (FEV1). The most up to date guideline, utilizing the GRADE methodology (European Respiratory Society guidelines of 2017), confirms their superiority over long acting β agonists (LABA) as monotherapy for COPD in that LAMA's have demonstrated greater efficacy in terms of exacerbation reduction, with similar safety profile.2 These recommnedations are supported by published peer-reviewed
evidence including individual papers and Cochrane reviews.
more
Infographics and data
Cureus 16(2): e53933. DOI 10.7759/cureus.53933
Diagnostics 2019, 9(4), 204; https://doi.org/10.3390/diagnostics9040204
The relative priority received by issues
in global health agendas is subjected to impressionistic
claims in the absence of objective methods of assessment
of priority. To build an approach for conducting structured
assessments of comparative priority health issues receive,
we expand the public
...
arenas model (2021) and offer a
framework for future assessments of health issue priority
in global and national health agendas.
more
According to the WHO, there were an estimated 251 million malaria cases (95% of global cases) and 579,414 malaria deaths (97% of global deaths) in African Union Member States in 2023. 76% of these deaths were children under the age of five.
A historic funding crisis is threatening to unravel decades of progress unless countries can make radical shifts to HIV programming and funding. The report highlights the impact that the sudden, large-scale funding cuts from international donors are having on countries most affected by HIV. Yet it a
...
lso showcases some inspiring examples of resilience, with countries and communities stepping up in the face of adversity to protect the gains made and drive the HIV response forward.
more
TCeci sont les lignes directrices unifiées sur la prévention, le diagnostic, le traitement et les soins de l’infection à VIH, de l’hépatite virale et des IST pour les populations clés (les hommes ayant des rapports sexuels avec des hommes, les personnes transgenres et de sexe variant, les t
...
ravailleurs du sexe, les consommateurs de drogues injectables et les personnes détenues en prison et dans d’autres milieux fermés). Elles présentent et discutent de nouvelles recommandations et consolident une série de recommandations et d'orientations issues des lignes directrices actuelles de l'OMS
more
В сводном руководстве изложены меры общественного здравоохранения применительно к ВИЧ-инфекции, вирусным гепатитам и инфекциям, передаваемым половым путем (ИПП
...
П), для пяти следующих ключевых групп населения: мужчины, практикующие половые контакты с мужчинами; трансгендерные и гендерно разнообразные люди; секс-работники и работницы; люди, употребляющие инъекционные наркотики; люди, находящиеся в местах лишения свободы и других учреждениях закрытого типа.
more
Technical Document
A Training Curriculum
a comprehensive guide
for the HCPs who work in counselling and psychological care of children and adoles-
cents. The Handbook includes information on HIV clinical care; growth and development;
mental health; child protection; counselling and communication; disclosure; loss, grief,
and bereavemen
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t; adherence; sexual and reproductive health; transition of care; support
systems; and monitoring and evaluation of psychosocial services. The material provided
in the Handbook aims to equip HCPs with important information that will help them to
maximise resiliency, minimise risk factors, and promote positive personal growth among
the children and adolescents they care for who are living with or affected by HIV.
more
Currently, there are only two manufacturers with HIV POC diagnostic products prequalified by the World Health
Organization (WHO) and eligible for procurement through the United Nations. UNICEF concluded its last tender for
HIV EID and VL POC diagnostic technologies in 2018 and awarded two manufact
...
urers long-term arrangements
(LTAs) to supply WHO prequalified product
more
A Guide for Community Case Workers in OVC Programs. This guide is meant to help you, a community case worker or
facility case manager working on an orphans and vulnerable children (OVC) program, to understand your role in supporting
multi-month dispensing (MMD) of anti-retroviral (ARV) medicines f
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or children and adolescents living with HIV (CLHIV/ALHIV).
more
Ukraine. Sitrep 2026: Fifth year of war: deepening humanitarian needs and impact on the HIV Response
As the war in Ukraine enters its fifth year, the humanitarian crisis continues to deepen, with profound consequences for access to essential services, including health care.
Modern warfare tactics, including the widespread use of drones and repeated attacks on critical infrastructure, are increasin
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g civilian harm and fundamentally reshaping how health services are delivered, especially in conflict-affected settings.
more
A Global Access Framework for Country-Led.
ResponsesThis 2030 Prevention access framework focuses on one of those top-line targets, which covers primary prevention and requires that 90% of people in need of HIV prevention are using effective prevention options by 2030. This target is disaggregated
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into 15 second-line prevention targets for specific populations and programmes.
The 2030 Prevention Access Framework presents in greater detail the milestones and actions for achieving these targets––all of which are grounded in the three priorities of the Global AIDS Strategy: country-led, resilient and sustainable HIV responses; people-focused services, and community leadership
more
Indicators and questions to monitor progress towards the Global AIDS Strategy 2026-2031 targets
Operational Guideline
How to Recognise and Manage Leprosy Reactions
recommended
This book is for all health workers who may have to help people who have nerve damage to their eyes, hands and feet. It will help them to encourage patients to develop a lifetime habit of caring for nerve-damaged parts.
