Revised and expanded version of the Guidelines
Багато людей, яким доводиться тікати від жахливої війни в Україні, приїжджають також до Німеччини. В чужій країні неодмінно виникає безліч питань, особливо щодо ас...ектів перебування, медичного забезпечення та соціальної інтеграції. У десяти відео ми даємо відповіді на найважливіші питання для біженців з України і беремо до уваги такі аспекти: життя з ВІЛ та/або туберкульозом, права представників ґендерних меншин, вживання наркотиків і замісна підтримувальна терапія, також робота у сфері інтим-послуг та біженство без українського паспорта.
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Viele Menschen, die vor dem furchtbaren Krieg in der Ukraine fliehen müssen, kommen auch nach Deutschland. In einem fremden Land treten unweigerlich viele Fragen auf, gerade hinsichtlich des Aufenthalts, gesundheitlicher Versorgung und gesellschaftlicher Aspekte. Wir geben in zehn Videos Antworten ...auf die wichtigsten Fragen für geflüchtete Menschen aus der Ukraine. Dabei berücksichtigen wir die Aspekte: Leben mit HIV und/oder Tuberkulose, queeres Leben, Drogenkonsum und Substitution sowie Sexarbeit und geflüchtete Menschen ohne ukrainischen Pass.
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Dieser Lagebericht ist eine Premiere und ich möchte als Integrationsbeauftragte und zugleich Antirassismusbeauftragte der Bundesregierung damit in bewegten, aufgewühlten Zeiten erklären und einordnen, mehr Verständigung und Verständnis schaffen. Erstmals liegt mit meinem
Bericht ein Dokument d...er Bundesregierung mit einer umfassenden Darlegung zu Rassismus in
Deutschland vor: mit Daten und Fakten, mit Analyse der Erscheinungsformen, mit Transparenz über Leerstellen bei Prävention, Beratung oder Forschung.
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Многие люди, которым приходится бежать от страшной войны в Украине, приезжают и в Германию. В чужой стране неизбежно возникает множество вопросов, особенно в отнош...нии проживания, медицинского обслуживания и социальных аспектов. В десяти видеороликах мы даем ответы на самые важные вопросы для беженцев из Украины. Мы учитываем следующие аспекты: жизнь с ВИЧ и/или туберкулезом, квир-жизнь, употребление наркотиков и заместительная терапия, а также секс-бизнес и беженцы без украинского паспорта.
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Chagas disease (CD) is endemic in the Americas, being present in 21 countries, where it affects about 6 million
people.(1) With such relevant numbers of people affected and disability adjusted life years lost, CD is a poverty-related
and poverty-promoting disease.
Although data describe a relevan...t ongoing public health problem for the American continent, significant results
in the interruption of transmission has been achieved by coordinated multi-country programs. In particular, the
Southern Cone Initiative (SCI), officially formalised in November 1991 by the Ministers of Health of Argentina, Brazil, Bolivia, Chile, Paraguay and Uruguay, has shown how a well-designed control program can significantly reduce
CD transmission.(2) Before this initiative, in these countries, there were 11 million infected persons and 50 million at
risk, 62% of the infected individuals of the whole continent.
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At the forefront of DNDi’s efforts to develop new treatments is the need to understand the realities and treatment needs of patients and health care staff in the field. The ultimate goal for human African trypanosomiasis (HAT) is a truly simplified
treatment which can be orally administered, impl...emented at the primary health care level, and effective against both stages of the disease.
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Chikungunya: WHO fact sheet on Chikungunya providing key facts and information on scope of the problem, who is at risk, prevention, WHO response.
Epidemiological Update
Dengue
7 February 2020
Situation summary
In the Region of the Americas, between epidemiological week (EW) 1 and EW 521 of 2019, a total of 3,139,335 cases of dengue have been reported (321.58 cases per 100,000 population), including 1,538 deaths. Of the total cases, 1,367,...353 (43.6%) were laboratory-confirmed and 28,169 (0.9%) were classified as severe dengue. The case-fatality rate was 0.049%.
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The aim of this toolkit is to guide countries on how to best estimate their current burden of dengue by combining existing data from dengue surveillance systems with on-going research efforts to measure the community burden
of dengue.
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery for HAT with special emphasis on the discovery, pre-clinical development, and operational challenge...s of the clinical trials of fexinidazole. The screening of the Drugs for Neglected Diseases initiative (DNDi) HAT-library by the Swiss TPH had singled out fexinidazole, originally developed by Hoechst (now Sanofi), as the most promising of a series of over 800 nitroimidazoles and related molecules. In cell culture, fexinidazole has an IC50 of around 1 µM against Trypanosoma brucei and is more than 100-fold less toxic to mammalian cells. In the mouse model, fexinidazole cures both the first, haemolymphatic, and the second, meningoencephalitic stage of the infection, the latter at 100 mg/kg twice daily for 5 days. In patients, the clinical trials managed by DNDi and supported by Swiss TPH mainly conducted in the Democratic Republic of the Congo demonstrated that oral fexinidazole is safe and effective for use against first- and early second-stage sleeping sickness. Based on the positive opinion issued by the European Medicines Agency in 2018, the WHO has released new interim guidelines for the treatment of HAT including fexinidazole as the new therapy for first-stage and non-severe second-stage sleeping sickness caused by Trypanosoma brucei gambiense (gHAT). This greatly facilitates the diagnosis and treatment algorithm for gHAT, increasing the attainable coverage and paving the way towards the envisaged goal of zero transmission by 2030.
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Dies ist der siebte Bericht über die Entwicklung der Menschenrechtssituation in Deutschland, den das Deutsche Institut für Menschenrechte („Institut“) jährlich dem Bundestag vorlegt. Der Bericht befasst sich in diesem Jahr vertieft mit dem Recht auf Bildung von Kindern und Jugendlichen mit Be...hinderungen. Wir analysieren die Frage, wie und mit welchem Instrumentarium Deutschland ein inklusives Schulsystem für alle schaffen kann. Denn dazu verpflichtet die UN-Behindertenrechtskonvention.
Hier sehen wir Bund und Länder gemeinsam in der Pflicht. Darüber hinaus greift der Bericht fünf weitere Themen auf, die im Berichtszeitraum (01. Juli 2021–30. Juni 2022) von hoher menschenrechtlicher Relevanz waren. Dabei stellen wir einerseits Entwicklungen in diesen Themenfeldern dar, andererseits bewerten wir wichtige politische und gesetzgeberische Maßnahmen menschenrechtlich und formulieren Empfehlungen.
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Anopheles stephensi, a highly competent vector of Plasmodium falciparum and P. vivax, is considered an efficient vector of urban malaria. Until 2011, the reported distribution of An. stephensi was confined to certain countries of South Asia and parts of the Arabian Peninsula. Since then, the vector ...has been collected in Djibouti (2012), Ethiopia (2016), Sudan (2016), Sri Lanka (2017), Somalia (2019), and most recently Nigeria (2020) and Yemen (2021). WHO considers the spread of An. stephensi to be a major potential threat to malaria control and elimination in Africa and southern Asia and has recently launched an initiative against the spread of this vector in Africa.
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Human African trypanosomiasis (HAT), or sleeping sickness, is a painful and protracted disease transmitted through the bite of infected tsetse flies and it is found in rural parts of sub-Saharan Africa. Sleeping sickness has two clinical phases but this review focuses only on treatment of the second...-stage, which is characterized by neurological changes and almost invariably fatal without treatment. There are only a few drugs currently available for second-stage sleeping sickness, all with considerable adverse events and variable efficacy.
The review includes nine trials with 2577 participants. Each trial reported different comparisons of the drugs currently available to treat second stage HAT (melarsoprol, eflornithine, nifurtimox) so no meta-analysis was possible.
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The Return Counselling Toolkit is a capacity-building instrument aimed at providing a harmonized and coherent approach to return counselling, based on key migrant-centred principles while protecting migrants’ rights. Mindful of the specific needs and rights pertaining to children, this additional ...module on counselling children and families further complements the first five modules of the Return Counselling Toolkit. It provides specialized guidance on how to prepare and deliver return counselling to accompanied, unaccompanied and separated children while upholding child rights and safeguards.
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States have committed and assumed obligations to address multiple and intersecting forms of discrimination against refugees, internally displaced persons, asylum seekers, returnees and stateless persons. The Global Compact on Refugees places ending discrimination of any kind based on the grounds of ...race, colour, sex, language, religion, political or other opinion, national or social origin, property, birth, disability, age, or other status at the centre of action to prevent displacement and to ensure peaceful coexistence between refugee and host communities. Narratives about cultural diversity and inclusion are important, but there is also a pressing need in many societies for conversations and action to address racism, racial discrimination, xenophobia and related intolerance.
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The sub-Saharan African region, carries 90% of the over 250 million cases of schistosomiasis occurring worldwide. In this region, after Nigeria, Tanzania is second country having the highest cases of schistosomiasis and approximately 51.5%0 of the Tanzanian population is either exposed or live in ar...eas with high risk of exposure. The country is endemic to both Schistosoma mansoni and Schistosoma haematobium, these infections are common in communities characterised with limited access to water, sanitation, hygienic practices and health services. Schistosoma mansoni infection is associated with hepatosplenic disease characterised with hepatomegaly, splenomegaly, progressive periportal fibrosis (PPF) which can lead to portal hypertension and its related sequelae, mainly ascites, liver surface irregularities, oesophageal varices and haematemesis. The main consequences of S. haematobium infection are haematuria, dysuria, nutritional deficiencies, urinary bladder lesions, hydronephrosis, urinary bladder squamous cell carcinoma and in children, growth retardation. Preventive chemotherapy using mass drug administration (MDA) of praziquantel targeting primary school aged children is the main strategy for controlling schistosomiasis in Tanzania.
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Human African trypanosomiasis is caused by Trypanosoma brucei gambiense in West and Central Africa and by T. brucei rhodesiense in East Africa; both species are endemic in Uganda. Trypanosoma brucei gambiense accounts for 98% of all cases of African trypanosomiasis, and T. brucei rhodesiense account...s for 2%. African trypanosomiasis has been targeted for eradication by the World Health Organization (WHO) and, as a result of control efforts, there has been a dramatic decrease (> 95%) in the number of reported cases worldwide.
Professional version as well as patient education
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DNDi’s long-term goal for sleeping sickness, also known as human African trypanosomiasis (HAT), is to develop and register two new drugs that are effective against both Stage 1 and Stage 2 of the disease and both subspecies of the parasite, T.b. gambiense and T.b. rhodesiense. T.b. rhodesiense is ...an acute form of the disease, occurring primarily in Eastern and Southern Africa. Better treatments for T.b. rhodesiense sleeping sickness are urgently needed.
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Plus de 700 000 personnes perdent la vie par suicide chaque année. La réduction d’un tiers du taux mondial de mortalité par suicide d’ici à 2030 est à la fois un indicateur et une cible (la seule pour la santé mentale) dans les objectifs de développement durable des Nations Unies et dans ...le Plan d’action global de l’OMS pour la santé mentale 2013–2030. Le treizième programme général de travail 2019–2023 de l’OMS comprend le même indicateur avec une réduction de 15 % à l’horizon 2023.
Le monde n’est pas sur la bonne voie pour atteindre les cibles de la réduction du suicide fixées pour 2030. L’OMS encourage les pays à prendre des mesures pour prévenir le suicide, idéalement par le biais d’une stratégie nationale intégrée de prévention du suicide. Les gouvernements et les communautés peuvent contribuer à la prévention du suicide en mettant en œuvre l’approche LIVE LIFE de l’OMS, dont le but est de servir de base pour commencer la prévention du suicide, et dont ils peuvent s’inspirer pour élaborer une stratégie nationale intégrée de prévention du suicide. Le présent guide s’adresse à tous les pays, qu’ils disposent actuellement ou non d’une stratégie nationale de prévention du suicide.
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