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Pretreatment drug resistance and new treatment paradigms in firstline ART

Moorhouse, M. Southern African HIV Cinicans Society (2018) C2
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Guidance for sampling art clinics in countries combing surveillance of Pre-Treatment HIV drug resistance and acquired HIV drug resistance at 12 and 48+ months

World Health Organization (2017) C_WHO
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Clinical, Virologic, Immunologic Outcomes and Emerging HIV Drug Resistance Patterns in Children and Adolescents in Public ART Care in Zimbabwe

A. T. Makadzange; M. Higgins-Biddle; B. Chimukangara; et al. PLOS One (2015) CC
PLOS ONE | DOI:10.1371/journal.pone.0144057 December 14, 2015
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Sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy

World Health Organization WHO (2022) C_WHO
WHO’s sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy is intended for easy and frequent implementation. Results from sentinel surveys provide insight into the prevalence and year-over-year trends of dolutegravir resi... more
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HIV drug resistance report 2021

World Health Organization (WHO) (2021) C_WHO
The HIV drug resistance report 2021 summarizes findings from 38 countries that had finalized the surveys by the time of this report and shared data with WHO. Pretreatment HIVDR to non-nucleoside reverse-transcriptase inhibitors (NNRTI) can affect more than 10% of adults starting therapy and is fo... more
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Introduction to ART

i-base (2018) C2
May 2018 HIV i-Base ISSN 1475-2077 www.i-Base.info Watch for out-of-date information First questions You and your doctor Resistance and adherence Treatment choices
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Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis

Zifodaya, J.; et al. Cochrane (2021) C1
Cochrane Database of Systematic Reviews 2021, Issue 2. Art. No.: CD009593. DOI: 10.1002/14651858.CD009593.pub5.
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Clinic-based survey of acquired HIV drug residence

World Health Organization WHO (2021) C_WHO
WHO’s antiretroviral treatment (ART) clinic-based acquired drug resistance survey method yields robust estimates of HIV viral suppression and acquired HIV drug resistance in adults, children and adolescents taking both dolutegravir and non-dolutegravir based regimens. Results are used to inform A... more
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HIV and Ebola Update

UNAIDS (2014)
It is essential that all people, including people living with HIV, are able to access health services and ongoing treatment. If people living with HIV who are on ART stop abruptly because they cannot access new supplies they could rapidly become unwell, drug resistance may build and the chances of o... more
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HIV Drug Resistance in infants, children and adolescents: Impact on treatment and outcomes

Fairlie, L. USAID (2017) CC
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Guidelines on the public health response to pretreatment HIV drug resistance

A. Lycett; D. Breuer; F. Verde; et al. World Health Organization (2017) C_WHO
Guidelines HIV drug resistance July 2017
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HIV Drug Resistance among virally unsuppressed respondents in the 5th South African National HIV Prevalence, Incidence, Behaviour and Communication Survey, 2017

Human Scientific Research Council HSRC South Africa (2018) C2
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HIV drug resistance strategy, 2021 update

World Health Organization WHO (2021) C_WHO
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Surveillance of HIV drug resistance in children newly diagnosed with HIV by early infant diagnosis. Concepte Note

World Health Organization WHO (2017) C_WHO
This concept note describes the methods used to assess the prevalence of any HIVDR and HIVDR by PMTCT exposure among children less than 18 months of age using remnant dried blood spot specimens from early infant diagnosis over a 12-month period
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Pre Exposure Prophylaxis (PrEP) and HIV Drug Resistance

Global Evaluation of Microbicide Sensitivity GEMS (2017) C2
Training materials for healthcare workers
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Directrices sobre la respuesta de salud pública a la farmacorresistencia del VIH previa al tratamiento. Julio 2017

Pan American Health Organization (PAHO) (2019) C_WHO
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HIV Drug Resistance Early Warning Indicators Survey in Ethiopia 2013/2014

Federal Democratic Republic of Ethiopia, Ministry of Health (2014) C1
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Tackling HIV Drug Resistance: Trends, guidelines and global action

World Health Organization WHO (2017) C_WHO
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Dolutegravir Resistance in Malawi’s National HIV Treatment Program

van Ossterhout, J. J.; Chipungu, C.; Nkhoma, L. et all. (2022) CC2
Dolutegravir HIV drug resistance (HIVDR) data from Africa remain sparse. We reviewed HIVDR results of Malawians on dolutegravir-based antiretroviral therapy (November 2020– September 2021). Of 6462 eligible clients, 33 samples were submitted to South Africa, 27 were sequenced successfully, and 8 ... more
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2019 ART Clinical Guidelines for the Management of HIV in Adults, Pregnancy, Adolescents, Children, Infants and Neonates

Deparment of Health, South Africa (2019) C1