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Sleeping Sickness - an introduction to African Trypanosomiasis

Let's learn about bugs (2017) C2
Video. Human African Trypanosomiasis, also known as sleeping sickness is a devastating parasitic disease. It is a neglected tropical disease affecting communities in Africa. In this video we take a look at the disease, how it presents and and ways to control it.
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Consensus & Evidence-Based INOSA GUIDELINES (INdian initiative on Obstructive Sleep Apnea Guidelines)

Department of Health Research Ministry of Health & Family Welfare (2014) C1
Guidelines on obstructive sleep apnea in India.
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Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy

Tirados, I.; Esterhuizen, J.; Kovacic, V.; Mangwiro, TNC.; Vale, GA et al. PLOS Neglected Tropical Diseases (2015) CC
Sleeping sickness is controlled by case detection and treatment but this often only reaches less than 75% of the population. Vector control is capable of completely interrupting HAT transmission but is not used because of expense. We conducted a full scale field trial of a refined vector control tec... more
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Sleep disorders in children and adolescents - A practical guide

S. Cortese; A. Ivanenko; U. Ramtekkar; et al. IACAPAP (2014) C2
Psychiatry and Pediatrics Chapter I.4
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Sleeping sickness : human African trypanosomiasis

World Health Organisation WHO (1997) C_WHO
Comic
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Sleeping sickness : human African trypanosomiasis. Arabic Version

World Health Organisation WHO (1999) C_WHO
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Sleeping Sickness. A fight against a nightmarish disease

University of Glasgow and Wellcome Trust (2026) CC
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About Sleeping Sickness

Centers for disease control and prevention CDC (2025) C_CDC
Key facts
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Human African trypanosomiasis (sleeping sickness)

World Health Organization WHO (2024) C_WHO
Human African trypanosomiasis (HAT), or sleeping sickness, is caused by trypanosome parasites that are transmitted by tsetse flies. HAT is found only in sub-Saharan Africa. Two subspecies of Trypanosoma brucei cause disease: T. b. gambiense in West and Central Africa, and T. b. rhodesiense in East A... more
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Indonesia: Association between sleep quality and obesity in adolescents

N. J. Sagala, S. Sofyani, Supriatmo Paediatrica Indonesiana (2017) C1
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African Trypanosomiasis (African Sleeping Sickness; Human African Trypanosomiasis; HAT)

Chelsea, M.; and W.A. Petri (2022) CC
MSD Manual Professional Version
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African Trypanosomiasis (African Sleeping Sickness; Human African Trypanosomiasis; HAT) Patient Information

Chelsea, M.; and W.A. Petri (2022) CC
MSD Manual Consumer Version
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Human African Trypanosomiasis (Sleeping Sickness). The Road to Elimination Revisited—Achievements and Remaining Challenges

Burri, E. MDPI (2020) CC
Printed Edition pdf
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Human African trypanosomiasis (sleeping sickness) Cinical Guidelines

Médecines sans Frontièrs MSF (2025) C1
Chapter in Clinical guidelines -Diagnosis and Treatment manual
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What is sleeping sickness? 

Drugs for Neglected Diseases Intiative DNDi (2025) CC
Accessed March, 2025
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Human African Trypanosomiasis (sleeping sickness): Current knowledge and future challenges

Papagni, R.; et al. (2023) CC
Front. Trop. Dis. , 09 May 2023 Sec. Neglected Tropical Diseases Volume 4 - 2023 | https://doi.org/10.3389/fitd.2023.1087003
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Fexinidazole for T.b. gambiense (Sleeping Sickness)

Drugs for Neglected Diseases initiative DNDi (2022) C2
DNDi is now striving to make fexinidazole available to the majority of people who have T.b. gambiense sleeping sickness. We are supporting a three-year access and pharmacovigilance study that began in 2020 and have so far carried out in-country training of relevant staff in 250 hospitals and... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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Strengthening the Role of Women with Disabilities in Humanitarian Action: A Facilitator’s Guide

B. Lee, E. Pearce, D. Buscher Women’s Refugee Commission (2017) C1
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Modelling the pandemic: attuning models to their contexts

Rhodes, T.; K. Lancaster; S. Lees et al. WHO (2020) C_WHO
BMJ Global Health2020;5:e002914. doi:10.1136/bmjgh-2020-002914 The evidence produced in mathematical models plays a key role in shaping policy decisions in pandemics. A key question is therefore how well pandemic models relate to their implementation contexts. Drawing on the cases of Ebola and in... more