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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Transforming Vision into Reality: The 2024 Global Alliance Progress Report on Ending AIDS in Children by 2030

UNAIDS (2024) CC

This status report shows how far we have come—and how much further we must go—if we hope to meet the global commitments to end AIDS in children. It offers a snapshot of global progress and permits an early assessment of the impact of the Global Alliance’s work.

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IASC Guidance, Addressing Suicide in Humanitarian Settings

Inter-Agency Standing Commitee (IASC) (2022) C2

This new guidance aims to support programme implementers, coordinators and others in humanitarian settings in their actions to counter suicide and self-harm in humanitarian contexts and to save lives.

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Malawi: National COVID-19 Preparedness and Response Strategy Plan (July 2021 - June 2022)

Government of Malawi (2021) CC

This new plan has been developed to build on successes made and lessons learnt from implementation of the two initial plans and to provide a short to medium term strategic anchor against which preparedness and response plans to the corona virus disease COVID-19 epidemic in the country should focus o... more

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A Decade of Destruction: Attacks on Health Care in Syria

Sider, R. , Buswell, M. , Al Salman, M. et al. International Rescue Committee, et al. (2021) CC

March 2021. “A Decade of Destruction: Attacks on health care in Syria,” highlights with chilling detail how this 10-year war strategy has turned hospitals from safe havens into no-go zones where Syrian civilians now fear for their lives.

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UNHCR Jordan: Zaatari Refugee Camp - Factsheet, January 2021

UN High Commissioner for Refugees UNHCR (2021) CC

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Challenges Faced by the Iraqi Health Sector in Respondingto COVID-19

Physicians for Human Rights (2021) CC

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Basic occupational safety and health for respiratory diseases

The Union (2021) C1

A desk guide for health facilities . It outlines a comprehensive approach to respiratory health, which health facilities can adapt and implement in resource-limited settings

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Regional guide for determining health workforce staffing norms and standards for health facilities

WHO Universal Health CoverageLife Course Cluster, WHO Regional Office WHO Regional Office for Africa (2021) C_WHO

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Health Care Waste Management Manual, Fourth Edition

Department of Health Philippines (2020) CC

This document shall serve as the most comprehensive set of guidelines on the safe management of waste generated from heath care activities in the country. It incorporates the requirements of all Philippine laws and regulations governing HCWM and is designed for the use of individuals, public and pri... more

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2020 Global AIDS Update ⁠— Seizing the moment ⁠— Tackling entrenched inequalities to end epidemics. Executive summary

UNAIDS (2020) C_WHO

The UNAIDS 2020 global report is a call to action. It highlights the scale of the HIV epidemic and how it runs along the fault lines of inequalities.

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PMTCT private sector engagement

SAATHII (Solidarity and Action Against The HIV Infection in India); Elizabeth Glaser Pediatric AIDS Foundation (2019) C2

Accessed: 30.10.2019

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Information bulletin no. 1 Americas: Population Movement August 2019

IFCR IFCR (2019) CC

In early 2015, the Americas region began to experience a surge in migration flows due in large part to the rise of people emigrating from Venezuela in response to the country’s faltering economy. This swell in migration continued in the years following, as the number of Venezuelans living in Latin... more

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Good practice framework for mental health and wellbeing in first responder organisations

Beyond Blue; Heads Up (2019) C2

Accessed April 2019

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Midterm performance evaluation of USAID’S Central Asia HIV program

United States Agency for International Development; D. Lowe, D. Hales; B. Herstad; B. Pick; A. Bolotbaeva; G. Jonboboeva USAID (From the American People) (2018) C2

October 2018 This publication was produced at the request of the United States Agency for International Development. It was prepared independently by David Lowe, David Hales, Britt Herstad, Billy Pick, Aisuluu Bolotbaeva, and Gulgun Jonboboeva.

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Young People and Mental Health in a Changing World

World Federation for Mental Health (WFMH) (2018) C1

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Training Guide and Skill Stations: Kenya Early Infant Male Circumcision Trainer’s Handbook

Ministry of Health, Kenya (2018) CC

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The roles, training and knowledge of community health workers about diabetes and hypertension in Khayelitsha, Cape Town

Tsollekile, L.P.; H. Schneider and T. Puoane Curationis (2018) CC

CONCLUSIONS: The roles performed by CHWs are broad, varied and essential for diabetes and hypertension management. However, basic knowledge about diabetes and hypertension remains poor while training is unstandardised and haphazard. These need to be improved if community-based NCD management is to b... more

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User experience analysis of e-TB Manager, a nationwide electronic tuberculosis recording and reporting system in Ukraine

N. Konduri, K. Sawyer, N. Nizova (2017) CC

ERJ Open Res 2017; 3: 00002-2017

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Out of step 2017

Médecins sans Frontières; Stop TB Partnership (2017) C3

TB policies in 29 Countries A survey of prevention, testing and treatment policies and practices