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Publication Years
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Category
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1
Toolboxes
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This report presents an analysis of antibacterial agents in preclinical (third annual review) and clinical (fifth annual review) development. The analysis covers traditional (direct-acting small molecules) and non-traditional antibacterial agents in development worldwide. It evaluates to what extent
...
the present pipeline addresses infections caused by WHO Priority Pathogens, Mycobacterium tuberculosis and Clostridioides difficile. The report also provides an assessment of the traditional agents with respect to whether they meet a set of predefined criteria for innovation, namely absence of known cross-resistance, new target, mode of action and/or class. It also includes an overview of the agents that obtained authorization since 1 July 2017.
more
This report’s central premise is that diagnostics and therapeutics, and associated test to treat strategies, are fundamental components of the pandemic response, both for COVID-19 and for future health threats. Two years into the COVID-19 pandemic, this report reflects on the main challenges and k
...
ey solutions on the road to equitable access to diagnostics and therapeutics.
This report draws from experience gained through the Access to COVID-19 Tools (ACT) Accelerator Diagnostics and Therapeutics pillars, and includes the perspectives of collaborating stakeholders (countries, civil society representatives and the private sector). Building on these findings, this report proposes sixteen recommended actions to address what have been identified as key structural challenges and specifies a potential owner for each action.
more
Leishmaniasis is a climate-sensitive disease. Changes in temperature, rainfall, and humidity can have strong impacts on
the sandfly vector, altering their distribution and influencing their survival and population sizes. Increased temperatures shorten vector development time, reduce Leishmania para
...
site incubation time, and increase vector biting rates, allowing transmission
in areas not previously endemic for the disease. Poor and
marginalized communities will be hit disproportionately harder by
the effects of climate change, and droughts, famines, and floods
can also lead to displacement and migration of immunologically
naive people to areas where leishmaniasis is endemic, posing a
threat of leishmaniasis outbreaks.
more
In May the Sixty-sixth World Health Assembly adopted resolution WHA66.12 (1) on 17 neglected tropical diseases (NTDs). Among other measures, the resolution urges Member States to:
• ensure country ownership of prevention, control, elimination and eradication programmes;
• expand and implemen
...
t interventions and advocate for predictable, long-term international financing for activities related to control and capacity strengthening;
• integrate control programmes into primary health-care services and existing programmes;
• ensure optimal programme management and implementation;
• achieve and maintain universal access to interventions and reach the targets of the roadmap.
more
In response to the recent publication “Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes” by Dadzie et al., it is important to clarify and highlight the positive and unequivocal research and operational contributio
...
ns from the American experience towards the worldwide elimination of human onchocerciasis (river blindness).
more
Accessed on 04.04.2023
The Drugs for Neglected Diseases initiative (DNDi) is an international
non-profit organization that discovers, develops, and delivers safe,
effective, and affordable treatments for the most neglected patients
A manual for impact assessments. The SCH Practical and Precision Assessment (SPPA) strategy is an evidence-based approach for conducting impact assessments for SCH. The SPPA was identified by programme managers and SCH experts from the African region as a feasible and sufficiently accurate approach
...
after reviewing and discussing the results of a multi-country study. This manual describes the resulting Practical and Precision Assessments approach and includes a discussion of the underlying concepts, factors to consider when determining what approach is appropriate, and how to interpret the collected data. The manual also includes annexes with standard operating procedures for conducting the stool and urine analyses.
more
The Pediatric Praziquantel Consortium was founded in July 2012 as the first international, non-profit, public-private partnership in schistosomiasis, supported by world leading experts in tropical parasitic infectious diseases.
Lancet. 2014 June 28; 383(9936): 2253–2264. doi:10.1016/S0140-6736(13)61949-2. Review Article
Schistosomiasis is a parasitic disease caused by infection with
Schistosoma trematodes. The disease affects poor rural communities
but has spread to urban areas and to tourists visiting endemic areas
Female Genital Schistosomiasis: a guide to inform equitable schistosomiasis control efforts in Ghana
Learning pack. This pack presents a summary of exploratory qualitative research methods and
findings from frontline health implementers and communities conducted by the
research team in Ghana.
The Lancet Volume 37100891September 2024. Free Download after registration
Breaking Barriers is an implementation research project focusing on social and behavioural change. It is conducted in conflict-affected communities in Cameroon. The project explores three innovative, community-based interventions designed to improve health behaviours. This presentation outlines the
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project's context, methodology and implementation process. It also shares qualitative insights and field perspectives, reflecting on key lessons learned for future SBC efforts in fragile settings.
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Poster
In this guide, the African Palliative Care Association (APCA) has put together evidence‑based information on the use of specific opioids commonly used in the management of moderate‑to‑severe pain to manage both cancer and non‑cancer pain. APCA hopes that this guide will be a useful tool i
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n aiding health professionals at all levels of healthcare delivery to assess and manage pain using opioids. All opioids included in this guide are listed on the WHO model list of essential medicines but we remind readers that oral morphine is the standard opioid of choice for managing moderate‑to‑severe pain and we recommend that it should be made available at all times.
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Poster presented CROI 2025
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes
organization of adolescent-friendly services to guide heath management teams and health
care workers (HCWs) on their roles. It also outlines important aspects to consider when
offering comprehensive care to adolescents an
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d their parents/caregivers at health facilities
and in the community. Comprehensive care should include the provision of quality clinical
and psychosocial support (PSS) services with clear linkages to the community. These
services need to be adolescent-friendly at any health facility with clear prescription of
minimal standards, and has to be integrated into existing services at the health facility
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Pocket guide
This World Health Organization (WHO) and the International Labour Organization (ILO) joint guidelines production aims at harnessing the contribution of employers and workers towards the control of TB. It covers all the practical steps involved in establishing TB control activities, including (for la
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rge employers) starting and running a workplace TB control programme. They are intended for use in all countries in which TB incidence is high and the target audience for the guidelines includes employers, employee organizations, NTP managers, and agencies providing technical support for TB control.
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