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Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand
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Neil M Ferguson, Daniel Laydon, Gemma Nedjati-Gilani, Natsuko Imai, Kylie Ainslie, Marc Baguelin, Sangeeta Bhatia, Adhiratha Boonyasiri, Zulma Cucunubá, Gina Cuomo-Dannenburg, Amy Dighe, Ilaria Dorigatti, Han Fu, Katy Gaythorpe, Will Green, Arran Hamlet, Wes Hinsley, Lucy C Okell, Sabine van Elsland, Hayley Thompson, Robert Verity, Erik Volz, Haowei Wang, Yuanrong Wang, Patrick GT Walker, Caroline Walters, Peter Winskill, Charles Whittaker, Christl A Donnelly, Steven Riley, Azra C Ghani. Imperial College COVID-19 Response Team (2020) C1

The global impact of COVID-19 has been profound, and the public health threat it represents is the most serious seen in a respiratory virus since the 1918 H1N1 influenza pandemic. Here we present the results of epidemiological modelling which has informed policymaking in the UK and other countries i... more

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2nd International Conference on Re-emerging Infectious Diseases: Scientific Report

African Union; Africa CDC Centres for Disease Control and Prevention Africa CDC (2019) C_CDC

In 2007, WHO warned that infectious diseases are emerging and re-emerging at a rate that has not been seen before. The potential for infectious diseases to spread rapidly results in high morbidity and mortality, causing a potential global public health treat of major concern. Several factors are ... more

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Antimicrobial resistance and the nurse’s role

Agne Diminskyte (2016) C2

Antimicrobial resistance is a global threat as it is present in all parts of the world and it means that there is a shortage of effective antibiotics to treat simple infections and diseases, also statistics reveal that because of antimicrobial resistance patients’ morbidity and mortality is increa... more

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The neglected zoonoses—the case for integrated control and advocacy

Welburn S. C., Beange I. et al (2015) C2

Clinical Microbiology and Infection Volume 21, Issue 5, May 2015, Pages 433-443; The neglected zoonotic diseases (NZDs) have been all but eradicated in wealthier countries, but remain major causes of ill-health and mortality across Africa, Asia, and Latin America. This neglect is, in part, a conse... more

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Situation Analysis and Recommendations: Antibiotic Use and Resitance in Mozambique

The Center for Disease Dynamics, Economics & Policy CDDEP (2015) C2

The Global Antibiotic Resistance Partnership (GARP)-Mozambique team, in partnership with the Center for Disease Dynamics, Economics & Policy (CDDEP), has produced this report as part of a solid com-mitment to develop actionable policy proposals to tackle antibiotic resistance and improve appropriate... more

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An end to violence against children

UN Children's Fund UNICEF United Nations and Partners (2012)

The full range and scale of all forms of violence against children are only now becoming visible, as is the evidence of the harm it does. This book documents the outcomes and recommendations of the process of the United Nations Secretary-General’s Study on Violence against Children. ‘The Study�... more

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Democratic Republic of the Congo Country Strategic Plan (2021–2024)

World Food Program WFP (2021) CC

Food and nutrition security in the Democratic Republic of the Congo is subject to the relentless impact of conflict, epidemics and climate events that have persisted in the country for decades, further compounded by the global COVID-19 pandemic. Lack of infrastructure and investment in agriculture, ... more

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Trends in UK meat consumption: analysis of data from years 1–11 (2008–09 to 2018–19) of the National Diet and Nutrition Survey rolling programme

Stewart C.; Piernas C.; Cook B.; et al. (2021) CC

High meat consumption, particularly red meat and processed meat, negatively affects our health, while meat production is one of the largest contributors to global warming and environmental degradation. The aim of our study was to explore trends in meat consumption within the UK and the associated ch... more

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Mixed Migration Review 2021: Reframing human mobility in a changing world. Message Summary

Mixed Migration Centre (2021) CC

The global migration context is rapidly changing with new conflicts and coups, new public health threats, new levels of environmental stress and changing perceptions around human mobility. Against that backdrop, migration policies, actions and attitudes are becoming more and more extreme, according ... more

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Evaluation of Child Friendly Spaces - An inter-agency series of impact evaluations in humanitarian emergencies (Research report)

UNICEF (2015) CC

Child friendly spaces (CFS) have become a widely used approach to protect and provide psychosocial support to children in emergencies. However, little evidence documents their outcomes and impacts. There is widespread commitment among humanitarian agencies to strengthen the evidence base of pr... more

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General Assembly: Progress on the prevention and control of non-communicable diseases

United Nations Secretary-General United Nations General Assembly (2017) C_WHO

The document, "Progress on the Prevention and Control of Non-Communicable Diseases," reports on global efforts to reduce the impact of NCDs, such as heart disease, cancer, diabetes, and chronic respiratory diseases, following the commitments made at high-level United Nations meetings. It highlights ... more

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Progress on the prevention and control of non-communicable diseases : report of the Secretary-General - arabic verison

United Nations Secretary-General United Nations General Assembly (2017) C_WHO

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Progress on the prevention and control of non-communicable diseases : report of the Secretary-General - chinese version

United Nations Secretary-General United Nations General Assembly (2017) C_WHO

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Progress on the prevention and control of non-communicable diseases : report of the Secretary-General - russian version

United Nations Secretary-General United Nations General Assembly (2017) C_WHO

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Cardiovascular disease risk profile and management practices in 45 low-income and middle-income countries: A cross-sectional study of nationally representative individual-level survey data

Peiris, D.; Ghosh, A.; Manne-Goehler, J. et al. PLoS Medicine (2021) CC

Global cardiovascular disease (CVD) burden is high and rising, especially in low-income and middle-income countries (LMICs). Focussing on 45 LMICs, we aimed to determine (1) the adult population’s median 10-year predicted CVD risk, including its variation within countries by socio-demographic char... more

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Geographic distribution of COPD prevalence in the world displayed by Geographic Information System maps

Blanco, I.; Diego, I.; Bueno, P. et al. (2019) CC2

Existing data on chronic obstructive pulmonary disease (COPD) prevalence are irregularly distributed around the world, and in many geographic regions data are scarce or even nonexistent. This fact hinders the implementation of adequate preventive and therapeutic interventions to reduce the high burd... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming

Williams, D.; Faiz, M.; Abela-Ridder, B. et al. PLoS Neglected Tropical diseases (2019) CC

In one of his final essays, statesman and former United Nations secretary general Kofi Annan said, ‘Snakebite is the most important tropical disease you’ve never heard of’. Mr. Annan firmly believed that victims of snakebite envenoming should be recognised and afforded greater efforts at impro... more

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Botswana National Integration Guidelines

United Nations Population Fund UNFPA (2022) C1

This Guideline, the first for the country, draws from national health sector reforms and integration agenda as outlined in the key national strategic documents. The Guide applies lessons learnt from the SRH/HIV Linkages project and its scale-up; other national experiences and from regional and globa... more

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Facilitating high quality acute care in resource- constrained environments: Perspectives of patients recovering from sepsis, their caregivers and healthcare workers in Uganda and Malawi

Limbani, F.; O. Kabajaasi, M. Basemera, et al. (2022) CC

PLOS Glob Public Health 2(8): e0000272. https://doi.org/10.1371/journal.pgph.0000272 Sepsis is a major global health problem, especially in sub-Saharan Africa. Improving patient care requires that healthcare providers understand patients’ priorities and provide quality care within the confines of... more

Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand recommended

Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand
recommended