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Addressing comorbidities and risk factors for tuberculosis (TB) is a crucial component of the World Health Organization (WHO)’s End TB Strategy. This WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities aims to support countries in scaling up
...
people-centred care, based on the latest WHO recommendations on TB and key comorbidities, and drawing upon additional evidence, best practices and inputs from various experts and stakeholders obtained during WHO processes. It is intended for use by people working in ministries of health, particularly TB programmes and the relevant departments or programmes responsible for comorbidities and health-related risk factors for TB such as HIV, diabetes, undernutrition, substance use, and tobacco use, as well as programmes addressing mental health and lung health. This operational handbook is a living document and will include a separate section for each of the key TB comorbidities or health-related risk factors. The third edition includes guidance for HIV-associated TB, mental health conditions and diabetes, which are three conditions strongly associated with TB and which result in higher mortality, poorer TB treatment outcomes and negatively impact health-related quality of life. The operational handbook aims to facilitate early detection, proper assessment and adequate management of people affected by TB and comorbidities. Full implementation of this guidance is expected to have a significant impact on TB treatment outcomes and health-related quality of life for people affected by TB.
more
The Ministry of Health through the National AIDS Secretariat, has developed the Strategic Operational Plan for Condom Programming in Sierra Leone with a focus on reinvigorating condom use to ensure “uninterrupted access to male and female condoms and lubricants for Key Populations, young
...
people and the general population.” Condom use in the country was estimated at 7 per cent and 23 per cent of women and men respectively who had sexual intercourse with non-regular partners. The primary goal of the strategic operational plan is to enhance access and utilization of male and female condoms, supporting national efforts to reduce the transmission of sexually transmitted infections (STIs), including HIV, and unintended pregnancies, for all sexually active individuals.
more
Trachoma is the leading infectious cause of blindness worldwide. In April 2023, it was a public health problem
in approximately 40 countries, with an estimated 116 million people at risk and 1.5 million p
...
eople affected
by the late blinding stage of the disease (1). About 84% of those at risk of trachoma are in the World Health
Organization (WHO)’s African Region; about 52% of those at risk of trachoma live in Ethiopia
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Trachoma is the world’s leading infectious cause of blindness. It is one of 18 neglected
tropical diseases (NTDs) that affect over one billion of the world’s poorest people.
The role of evidence in the journey towards universal health coverage is paramount. Financial risk protection monitoring, the major focus of this report, informs where the WHO African Region stands in reducing the financial hardship people face due
...
to health expenses. This report details the status of financial risk protection and related trends, the drivers of out-of-pocket (OOP) payments and the impact of the COVID-19 pandemic on financial risk protection. As such, it provides evidence coutries can draw on to develop health financing systems and reforms that mitigate financial barriers to accessing health services. Through analysis of country data, cross-country learning and drawing on the published literature, this report proposes recommendations that countries may adapt to their contexts.
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This video explores the impact of rapid urbanisation on the transmission of malaria, highlighting that, although the burden of malaria remains highest in rural areas, the majority of people in malaria-endemic countries will soon reside in urban area
...
s. It explains how well-planned urbanisation can reduce malaria by improving access to healthcare and infrastructure, whereas rapid, unplanned urban growth may increase the risk, particularly among the urban poor.
more
This educational video provides an overview of malaria, including its causes, symptoms and how it is transmitted. It focuses on the most vulnerable groups: children under five, pregnant women, people living with HIV/AIDS, and travellers or migrants.
...
Using engaging visuals and background music, the video emphasises the importance of prevention strategies such as insecticide-treated bed nets, antimalarial medication and raising public awareness.
more
Offering additional pre-exposure prophylaxis (PrEP) choices has the potential to increase uptake and effective use of PrEP, and of HIV prevention overall, as it allows people to choose a method that they prefer.
In this guideline, WHO recommends
...
an offering long-acting injectable lenacapavir (LEN) as an additional HIV prevention choice, as part of combination HIV prevention approaches. LEN, administered twice a year as PrEP, has been shown to be highly effective at reducing the risk of HIV acquisition. In this guideline, WHO also recommends using HIV rapid diagnostic tests (RDTs) for individuals initiating or continuing long-acting injectable PrEP, such as LEN and long acting injectable cabotegravir (CAB-LA). Flexible HIV testing approaches are essential for ensuring that testing does not become a barrier to accessing or continuing PrEP, including long-acting injectable options.
more
This document highlights the latest WHO recommendations designed to optimize health outcomes, streamline delivery and address persistent barriers to prevention and care. It especially focuses on people often left behind in service delivery, includin
...
g adolescents and young people, key populations and people with advanced HIV disease. The guidance emphasizes integration, simplification, choice and equity.
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The Gaza Strip is experiencing one of the most severe food security crises globally, with the entire population of approximately 2.1 million people now facing crisis-level food insecurity or worse (IPC Phase 3+). As of May 2025, more than one in fiv
...
e Gazans—about
470,000 people—are at risk of starvation (IPC Phase 5: Catastrophe), while over half are classified in Emergency (IPC Phase 4). This marks a significant deterioration compared to just one month earlier and reflects the impact of a comprehensive blockade that has
restricted all humanitarian and commercial supplies since early March. Vital goods have been depleted, food prices have skyrocketed by over 3,000 percent in some areas, and coping mechanisms have all but collapsed, forcing many to scavenge for food or go without entirely. Acute malnutrition has reached serious levels and is projected to worsen, particularly in North Gaza, Gaza, and Rafah, where critical levels are expected between May and September 2025.
more
The Gaza Strip is experiencing one of the most severe food security crises globally, with the entire population of approximately 2.1 million people now facing crisis-level food insecurity or worse (IPC Phase 3+). As of May 2025, more than one in fiv
...
e Gazans—about
470,000 people—are at risk of starvation (IPC Phase 5: Catastrophe), while over half are classified in Emergency (IPC Phase 4). This marks a significant deterioration compared to just one month earlier and reflects the impact of a comprehensive blockade that has restricted all humanitarian and commercial supplies since early March. Vital goods have been depleted, food prices have skyrocketed by over 3,000 percent in some areas, and coping mechanisms have all but collapsed, forcing many to scavenge for food or go without entirely. Acute malnutrition has reached serious levels and is projected to worsen, particularly in North Gaza, Gaza, and Rafah, where critical levels are expected between May and September 2025.
more
In 2012, 25.7% of adults in Tanzania aged 25–64 had hypertension, affecting approximately 4 million people. However, most remain unaware of their condition or are not receiving treatment, with only 0.1 million achieving blood pressure control.
Despite being a preventable and curable infectious disease, tuberculosis (TB) has continued to elude global controll efforts. In 2023, 8.2 milion people with TB were diagnosed and notified to the WHO, the hightest number ever reported since WHO bega
...
n tracking.
more
Buruli ulcer (BU) is a skin-related neglected tropical disease (skin NTD) caused by infection with
Mycobacterium ulcerans. BU is the third most common mycobacterial disease after tuberculosis and leprosy
in people who are not immunocompromised. Th
...
e infection manifests in non-ulcerative forms as nodules,
plaques and/or oedemas, which ulcerate within 4–6 weeks and display characteristic undermined edges and yellowish-white necrotic slough . Most lesions occur on the lower limbs.
more
Exposure to air pollution has significant adverse health effects, leading to nearly 1 in every 8 deaths globally. Air pollution affects all age groups, from unborn children to older people, in both high- and low-income nations.
The annual bulletin of the Mekong Malaria Elimination (MME) programme is a yearly report that reviews ongoing efforts to combat multidrug resistance and eliminate malaria in the 6 countries of the Greater Mekong subregion (GMS): Cambodia, China (Yunnan province), Lao
...
People's Democratic Republic, Myanmar, Thailand and Viet Nam.
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The Mekong Malaria Elimination (MME) programme is an initiative aimed at supporting Greater Mekong Subregion (GMS) countries – Cambodia, Lao People's Democratic Republic, Myanmar, Thailand, Viet Nam, and Yunnan (China) – in achieving the goal of
...
malaria elimination by 2030. Data for this epidemiological summary were compiled from country reports. Between July and September 2024, 48 115 malaria cases were reported. During that period, GMS countries recorded 44% fewer cases, with P. falciparum + mixed and P. vivax cases declining by 81% and 36%, respectively. Meanwhile, testing declined by 25% when compared to the same period in 2023.
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HUMANITIES AND SOCIAL SCIENCES COMMUNICATIONS | (2022)9:295 | https://doi.org/10.1057/s41599-022-01312-3 .
Sub-Saharan Africa (SSA), particularly Southern and East Africa, has the highest AIDS deaths
and HIV-infected people in the world. Even tho
...
ugh considerable effort has been made over
the years to study HIV transmission risk behaviours of different population groups in SSA,
there is little evidence of studies that have looked at pooled effects of associated HIV risk
factors among men, particularly in Southern Africa.
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Communities are at the heart of every response. Effective risk communication and community engagement (RCCE) supports communities and individuals in understanding the risks they face and making informed decisions about how to protect themselves and the peo
...
ple around them. Accurate information, provided to communities in ways they understand and respect, builds trust and supports the success of prevention, response and recovery efforts.
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With an estimated population of about 5 million and an annual growth rate of 8 per cent, Dar es Salaam, Tanzania, is Africa’s fastest growing city.1 Over 70 per cent of the people live in informal, unplanned settlements with inadequate infrastr
...
ucture. In addition, heavy rainfalls twice a year result in signifi cant fl ood risks. The objectives in Dar es Salaam were to 1) obtain high quality and up to date exposure maps of aff ected communities and as a stretch goal 2) to create a hydrological model using elevation data. Both of these would form important elements to managing fl ood risks but neither had been previously available due to a lack of high quality digital imagery
more
